Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Steven G Gray"'
Autor:
Tomer Meirson, Valerio Nardone, Francesca Pentimalli, Gal Markel, David Bomze, Maria D’Apolito, Pierpaolo Correale, Antonio Giordano, Luigi Pirtoli, Camillo Porta, Steven G Gray, Luciano Mutti
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-9 (2022)
Abstract In this commentary, using existing clinical trial data and FDA approvals we propose that there is currently a critical need for an appropriate balancing between the financial impact of new cancer drugs and their actual benefit for patients.
Externí odkaz:
https://doaj.org/article/31b55a1ccc204e26bbba66e8945e4d5e
Autor:
Martin P Barr, Steven G Gray, Andreas C Hoffmann, Ralf A Hilger, Juergen Thomale, John D O'Flaherty, Dean A Fennell, Derek Richard, John J O'Leary, Kenneth J O'Byrne
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233739 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0054193.].
Externí odkaz:
https://doaj.org/article/7a367a85752245de8d7ced145da0ab40
Autor:
Martin P Barr, Steven G Gray, Andreas C Hoffmann, Ralf A Hilger, Juergen Thomale, John D O'Flaherty, Dean A Fennell, Derek Richard, John J O'Leary, Kenneth J O'Byrne
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54193 (2013)
IntroductionInherent and acquired cisplatin resistance reduces the effectiveness of this agent in the management of non-small cell lung cancer (NSCLC). Understanding the molecular mechanisms underlying this process may result in the development of no
Externí odkaz:
https://doaj.org/article/18af4cd6dbdb4d73aa78e1b2488d6a3e
Autor:
Casey M Wright, Michaela B Kirschner, Yuen Yee Cheng, Kenneth J O'Byrne, Steven G Gray, Karin Schelch, Mir Alireza Hoda, Sonja Klebe, Brian McCaughan, Nico van Zandwijk, Glen Reid
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70940 (2013)
Malignant Pleural Mesothelioma (MPM) is an aggressive cancer that is often diagnosed at an advanced stage and is characterized by a long latency period (20-40 years between initial exposure and diagnosis) and prior exposure to asbestos. Currently acc
Externí odkaz:
https://doaj.org/article/3ebd2a49ba434e608635b5f85e36deac
Autor:
Dario Barbone, Priscilla Cheung, Sailaja Battula, Sara Busacca, Steven G Gray, Daniel B Longley, Raphael Bueno, David J Sugarbaker, Dean A Fennell, V Courtney Broaddus
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52753 (2012)
When grown in 3D cultures as spheroids, mesothelioma cells acquire a multicellular resistance to apoptosis that resembles that of solid tumors. We have previously found that resistance to the proteasome inhibitor bortezomib in 3D can be explained by
Externí odkaz:
https://doaj.org/article/b703b0b889704046ba0ae5a2b127ba63
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14593 (2011)
BACKGROUND:Angiogenesis may play a role in the pathogenesis of Non-Small Cell Lung cancer (NSCLC). The CXC (ELR(+)) chemokine family are powerful promoters of the angiogenic response. METHODS:The expression of the CXC (ELR(+)) family members (CXCL1-3
Externí odkaz:
https://doaj.org/article/f52796ac24d04638b9cfc843db5d5060
Autor:
Anna Keogh, Lisa Ryan, Mutaz M. Nur, Anne-Marie Baird, Siobhan Nicholson, Sinéad Cuffe, Gerard J. Fitzmaurice, Ronan Ryan, Vincent K. Young, Stephen P. Finn, Steven G. Gray
Publikováno v:
Translational Lung Cancer Research. 11:1877-1895
USO1 vesicle transport factor (USO1) is a vesicular transport factor crucial for endoplasmic reticulum (ER) to Golgi transport and is required for transcytotic fusion and subsequent binding of the vesicles to the target membrane. USO1 has been studie
Autor:
Bandar Alharbi, Husam Qanash, Naif K. Binsaleh, Salem Alharthi, Abdulbaset M. Elasbali, Chandranil H. Gharekhan, Muhammad Mahmoud, Emmanouil Lioudakis, John J. O’Leary, Derek G. Doherty, Bashir M. Mohamed, Steven G. Gray
Publikováno v:
Scientific Reports. 13
Immunotherapies, including immune checkpoint inhibitors, have limitations in their effective treatment of malignancies. The immunosuppressive environment associated with the tumor microenvironment may prevent the achievement of optimal outcomes for i
Autor:
Kristen Orumaa, Steven G. Gray
Publikováno v:
Epigenetic Cancer Therapy ISBN: 9780323913676
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ab2500f316ac6b19e78564394b386c
https://doi.org/10.1016/b978-0-323-91367-6.00008-8
https://doi.org/10.1016/b978-0-323-91367-6.00008-8
Autor:
Anne-Marie Baird, Steven G. Gray
Publikováno v:
Epigenetic Cancer Therapy ISBN: 9780323913676
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3a2fc03612fbfe55b63b197d002e55c
https://doi.org/10.1016/b978-0-323-91367-6.00026-x
https://doi.org/10.1016/b978-0-323-91367-6.00026-x