Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Steven F. Komjathy"'
Autor:
S. Aubrey Stoch, Steven F. Komjathy, Sarah Robertson, Edward O'Mara, Donald Heald, Lichuan Liu, Mark J. Dresser, Mark Rogge, Akintunde Bello
Publikováno v:
Journal of clinical pharmacology. 56(2)
Ketoconazole has been widely used as a strong cytochrome P450 (CYP) 3A (CYP3A) inhibitor in drug-drug interaction (DDI) studies. However, the US Food and Drug Administration has recommended limiting the use of ketoconazole to cases in which no altern
Autor:
Brian Michael Mathes, Zhixiang Yang, Dustin J. Mergott, Scott A. Monk, Hykop Gevorkyan, Larry Ereshefsky, Vaught Grant Matthews, Leonard L. Winneroski, Jon A. Erickson, Stephen L. Lowe, Celedon Gonzales, Scott Martin Sheehan, David E. Timm, Brian Morgan Watson, Ferenc Martenyi, David O. Calligaro, Stephanie L. Stout, Theresa A. Day, Richard A. Brier, Patrick J Cocke, Brian A. Willis, Stanford Jhee, Leonard N. Boggs, Robert A. Dean, James E. Audia, Steven F. Komjathy, Anthony R. Borders, Terry D. Lindstrom, Patrick C. May, Douglas E. James, Linglin Li
BACE1 is a key protease controlling the formation of amyloid β, a peptide hypothesized to play a significant role in the pathogenesis of Alzheimer's disease (AD). Therefore, the development of potent and selective inhibitors of BACE1 has been a focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78c69adc5fae76e66024d7197aeccfc
https://europepmc.org/articles/PMC6605527/
https://europepmc.org/articles/PMC6605527/
Autor:
Steven F. Komjathy, Victor L. Serebruany, Helen J. Scott, William R. Herzog, Matthew L. Schlossberg, David C. Sane, Maureen E. Collins, Paul A. Gurbel
Publikováno v:
Journal of Thrombosis and Thrombolysis. 1:187-194
Background: Myocardial reperfusion after short durations of ischemia causes prolonged contractile dysfunction (myocardial stunning). Recently it has also been suggested that ischemia-reperfusion results in impaired coronary endothelial function. Sinc
Autor:
Steven F. Komjathy, Gregory C. Williams, William B. Smith, Diane R. Mould, Mark S. Sumeray, Ming-yi Hu, Thomas Marbury
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Clevidipine is a rapidly-acting intravenous dihydropyridine antihypertensive acting via calcium channel blockade. This was a randomized, single-blind, parallel-design study of a 72-h continuous clevidipine infusion. Method Doses of 2, 4, 8, o