Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Steven F. Baker"'
Autor:
Gloria P. Larson, Vy Tran, Shuǐqìng Yú, Yíngyún Caì, Christina A. Higgins, Danielle M. Smith, Steven F. Baker, Sheli R. Radoshitzky, Jens H. Kuhn, Andrew Mehle
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2175-2183.e4 (2019)
Summary: All viruses balance interactions between cellular machinery co-opted to support replication and host factors deployed to halt the infection. We use gene correlation analysis to perform an unbiased screen for host factors involved in influenz
Externí odkaz:
https://doaj.org/article/c1bec00affbc4b76bbe599ad26f94b56
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2581-2588.e4 (2018)
Summary: Adaptation of viruses to their hosts can result in specialization and a restricted host range. Species-specific polymorphisms in the influenza virus polymerase restrict its host range during transmission from birds to mammals. ANP32A was rec
Externí odkaz:
https://doaj.org/article/4634c5b8b6a94e1596c2943656e913f4
Publikováno v:
Viruses, Vol 8, Iss 7, p 179 (2016)
Influenza A viruses (IAV) cause annual seasonal human respiratory disease epidemics. In addition, IAV have been implicated in occasional pandemics with inordinate health and economic consequences. Studying IAV, in vitro or in vivo, requires the use o
Externí odkaz:
https://doaj.org/article/e4e70ea5fd854fc5ad4424e02ae10bd0
Autor:
Steven F Baker, Helene Meistermann, Manuel Tzouros, Aaron Baker, Sabrina Golling, Juliane Siebourg Polster, Mitchell P Ledwith, Anthony Gitter, Angelique Augustin, Hassan Javanbakht, Andrew Mehle
Publikováno v:
PLoS Biology, Vol 20, Iss 12, p e3001934 (2022)
Viruses must balance their reliance on host cell machinery for replication while avoiding host defense. Influenza A viruses are zoonotic agents that frequently switch hosts, causing localized outbreaks with the potential for larger pandemics. The hos
Externí odkaz:
https://doaj.org/article/09649af87e6d41eaa961fc4a034da8e8
Publikováno v:
Seminars in Cell & Developmental Biology. 146:40-56
Effector CD8+T cell interactions are critical in controlling viral infection by directly killing infected cells but overabundant or sustained activation also exacerbates tissue damage. Chemokines promote the trafficking of effector CD8+T cells into i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a13ee6103552f1668135d0b31e6fd5f
https://doi.org/10.1101/2022.09.13.507813
https://doi.org/10.1101/2022.09.13.507813
Autor:
Juliane Siebourg Polster, Angélique Augustin, Hassan Javanbakht, Sabrina Golling, Mitchell P. Ledwith, Manuel Tzouros, Andrew Mehle, Aaron Baker, Anthony Gitter, Steven F. Baker, Hélène Meistermann
Viruses must balance their reliance on host cell machinery for replication while avoiding host defense. They often exploit conserved essential host genes whose critical role for the cell limits mutational escape. Conversely, host antiviral genes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a41d5b6afe19e84ebb2656613768a7a
https://doi.org/10.1101/2020.11.09.355982
https://doi.org/10.1101/2020.11.09.355982
Autor:
Andrew Mehle, Steven F. Baker
Publikováno v:
eLife, Vol 8 (2019)
The evolutionary history of ANP32 proteins impacts how influenza virus jumps from birds to mammals.
Autor:
Christina A. Higgins, Steven F. Baker, Sheli R. Radoshitzky, Vy Tran, Jens H. Kuhn, Andrew Mehle, Shuǐqìng Yú, Yíngyún Caì, Danielle M. Smith, Gloria P. Larson
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 8, Pp 2175-2183.e4 (2019)
Cell Reports, Vol 29, Iss 8, Pp 2175-2183.e4 (2019)
SUMMARY All viruses balance interactions between cellular machinery co-opted to support replication and host factors deployed to halt the infection. We use gene correlation analysis to perform an unbiased screen for host factors involved in influenza
Mutations at highly conserved residues in influenza A(H1N1)pdm09 virus affect neuraminidase activity
Autor:
Leidi C. Alvarez-Sánchez, Laura Conde-Ferráez, Guadalupe Ayora-Talavera, Refugio González-Losa, Lesly Romero-Beltran, Marylin Puerto-Solís, Steven F. Baker, Luis Martinez-Sobrido
Publikováno v:
Virus Research. 225:1-9
Influenza virus neuraminidase (NA) plays a pivotal role during viral growth since its sialidase activity allows the efficient release of nascent virions from infected cells. Consequently, mutations in the NA catalytic site affecting sialic acid (SA)