Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Steven F, Gameiro"'
1
Akademický článek
HPV16 Intratypic Variants in Head and Neck Cancers: A North American Perspective
Autor: Steven F. Gameiro, Mikhail Y. Salnikov, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v: Viruses, Vol 15, Iss 12, p 2411 (2023)
Human papillomavirus (HPV) is the major causative agent for cervical and many head and neck cancers (HNCs). HPVs randomly acquire single nucleotide polymorphisms (SNPs) that may become established via positive selection. Within an HPV type, viral iso
Externí odkaz: https://doaj.org/article/8cdc15fdb1154c088967c5e89ad98748
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2
Akademický článek
The HPV Induced Cancer Resource (THInCR): a Suite of Tools for Investigating HPV-Dependent Human Carcinogenesis
Autor: Mikhail Salnikov, Steven F. Gameiro, Peter Y. F. Zeng, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v: mSphere, Vol 7, Iss 4 (2022)
ABSTRACT Human papillomaviruses (HPVs) are highly infectious and cause the most common sexually transmitted viral infections. They induce hyperproliferation of squamous epithelial tissue, often forming warts. Virally encoded proteins reprogram gene e
Externí odkaz: https://doaj.org/article/2657d1b773dc485f89420a45ebcca125
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3
Akademický článek
Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis
Autor: Steven F. Gameiro, Farhad Ghasemi, Peter Y. F. Zeng, Neil Mundi, Christopher J. Howlett, Paul Plantinga, John W. Barrett, Anthony C. Nichols, Joe S. Mymryk
Publikováno v: Infectious Agents and Cancer, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Frequent mutations in the nuclear receptor binding SET domain protein 1 (NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC). NSD1 encodes a histone 3 lysine-36 methyltransferase. NSD1 mutations are cor
Externí odkaz: https://doaj.org/article/74f93a6ff6cd4c05bdc90a39355af0e2
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4
Akademický článek
High Levels of Class I Major Histocompatibility Complex mRNA Are Present in Epstein–Barr Virus-Associated Gastric Adenocarcinomas
Autor: Farhad Ghasemi, Steven F. Gameiro, Tanner M. Tessier, Allison H. Maciver, Joe S. Mymryk
Publikováno v: Cells, Vol 9, Iss 2, p 499 (2020)
Epstein−Barr virus (EBV) is responsible for approximately 9% of stomach adenocarcinomas. EBV-encoded microRNAs have been reported as reducing the function of the class I major histocompatibility complex (MHC-I) antigen presentation apparatus, which
Externí odkaz: https://doaj.org/article/7392a9ce40764e83b96ec8563bd60fcf
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5
Akademický článek
Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy
Autor: Steven F. Gameiro, Farhad Ghasemi, John W. Barrett, James Koropatnick, Anthony C. Nichols, Joe S. Mymryk, Saman Maleki Vareki
Publikováno v: OncoImmunology, Vol 7, Iss 10 (2018)
Cancers progress when the immune system fails to identify and eliminate malignant cells. Recognition of this, combined with advances in tumor immunology, has allowed development of therapies that induce effective anti-tumor immune responses. For inco
Externí odkaz: https://doaj.org/article/6629c6170264484689f69b3dd6ec5618
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6
Akademický článek
Hacking the Cell: Network Intrusion and Exploitation by Adenovirus E1A
Autor: Cason R. King, Ali Zhang, Tanner M. Tessier, Steven F. Gameiro, Joe S. Mymryk
Publikováno v: mBio, Vol 9, Iss 3 (2018)
ABSTRACT As obligate intracellular parasites, viruses are dependent on their infected hosts for survival. Consequently, viruses are under enormous selective pressure to utilize available cellular components and processes to their own advantage. As mo
Externí odkaz: https://doaj.org/article/2f6c2011fd9c404c8566703b333ccfb0
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7
HPV-Positive and -Negative Cervical Cancers Are Immunologically Distinct
Autor: Andris M. Evans, Mikhail Salnikov, Steven F. Gameiro, Saman Maleki Vareki, Joe S. Mymryk
Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 16; Pages: 4825
Although infection with human papillomavirus (HPV) is associated with nearly all cervical cancers (CC), a small proportion are HPV-negative. Recently, it has become clear that HPV-negative CC represent a distinct disease phenotype compared to HPV-pos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a599ed667e20a53c8be938b0f7544c
https://pubmed.ncbi.nlm.nih.gov/36013065
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8
Akademický článek
The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species
Autor: Ali Zhang, Tanner M. Tessier, Kristianne J. C. Galpin, Cason R. King, Steven F. Gameiro, Wyatt W. Anderson, Ahmed F. Yousef, Wen T. Qin, Shawn S. C. Li, Joe S. Mymryk
Publikováno v: Viruses, Vol 10, Iss 12, p 662 (2018)
Early region 1A (E1A) is the first viral protein produced upon human adenovirus (HAdV) infection. This multifunctional protein transcriptionally activates other HAdV early genes and reprograms gene expression in host cells to support productive infec
Externí odkaz: https://doaj.org/article/e2a82a22769b44a1bbde18b87a862c8a
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10
The tumor immune microenvironments of HPV
Autor: Steven F, Gameiro, Andris M, Evans, Joe S, Mymryk
Publikováno v: WIREs mechanisms of diseaseREFERENCES. 14(2)
Human papillomaviruses (HPVs) are the etiological agent of a significant, and increasing, fraction of head and neck squamous cell carcinomas (HNSCC)-a heterogenous group of malignancies in the head and neck region. HPV infection accounts for approxim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c083f92548cdd83469ce1b5fcf49e14b
https://pubmed.ncbi.nlm.nih.gov/35030304
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