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pro vyhledávání: '"Steven Edenson"'
Publikováno v:
Cancer Research. 83:6651-6651
Immune checkpoint (IC) receptors play critical roles in maintaining immune homeostasis and have emerged as proven therapeutic targets for the treatment of various cancers and autoimmune disorders. Monoclonal antibodies (mAbs) designed to block immune
Autor:
Jamison Grailer, Julia Gilden, Jun Wang, Denise Garvin, Pete Stecha, Jim Hartnett, Steven Edenson, Frank Fan, Mei Cong, Zhi-jie Jey Cheng
Publikováno v:
Cancer Research. 82:1875-1875
Programmed death 1 (PD-1) is an immune checkpoint (IC) receptor that negatively regulates T-cell immune function. Blocking the interaction of PD-1 with its ligand PD-L1 unleashes the immune system and enhances anti-tumor responses. Immunotherapy usin
Autor:
Steven Edenson
Publikováno v:
The FASEB Journal. 34:1-1