Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Steven E. Stayrook"'
Autor:
Iris K. van Alderwerelt van Rosenburgh, David M. Lu, Michael J. Grant, Steven E. Stayrook, Manali Phadke, Zenta Walther, Sarah B. Goldberg, Katerina Politi, Mark A. Lemmon, Kumar D. Ashtekar, Yuko Tsutsui
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Although small molecule tyrosine kinase inhibitors are effective in lung cancer driven by mutated EGFR, some receptor variants fail to respond. Here, the authors identify structural features of an important set of EGFR variants with reduced inhibitor
Externí odkaz:
https://doaj.org/article/b04886b84f654ae4b677dfc2b5e44cc2
Autor:
Nathan M. Ennist, Zhenyu Zhao, Steven E. Stayrook, Bohdana M. Discher, P. Leslie Dutton, Christopher C. Moser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
De novo development of a simplified photosynthetic reaction center protein can clarify practical engineering principles needed to build enzymes for efficient energy conversion. Here, the authors develop an artificial photosynthetic reaction center th
Externí odkaz:
https://doaj.org/article/ecdd0ca5f37f4717bc903f4f1fb1bb45
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
New technologies for efficient solar-to-fuel energy conversion will help facilitate a global shift from dependence on fossil fuels to renewable energy. Nature uses photosynthetic reaction centers to convert photon energy into a cascade of electron-tr
Externí odkaz:
https://doaj.org/article/5d9ffd0e31194d27942cee1805e0842b
Autor:
Fumin Shi, Jeannine M. Mendrola, Joshua B. Sheetz, Neo Wu, Anselm Sommer, Kelsey F. Speer, Jasprina N. Noordermeer, Zhong-Yuan Kan, Kay Perry, S. Walter Englander, Steven E. Stayrook, Lee G. Fradkin, Mark A. Lemmon
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109834- (2021)
Summary: WNTs play key roles in development and disease, signaling through Frizzled (FZD) seven-pass transmembrane receptors and numerous co-receptors including ROR and RYK family receptor tyrosine kinases (RTKs). We describe crystal structures and W
Externí odkaz:
https://doaj.org/article/0a50f419840142aeb7b781200e52336f
Publikováno v:
Angewandte Chemie; Jul2006, Vol. 118 Issue 30, p5073-5076, 4p