Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Steven E. Shoelson"'
Autor:
Janna A. van Diepen, Man C. Wong, Bruno Guigas, Jasper Bos, Rinke Stienstra, Leanne Hodson, Steven E. Shoelson, Jimmy F.P. Berbée, Patrick C.N. Rensen, Johannes A. Romijn, Louis M. Havekes, Peter J. Voshol
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 5, Pp 942-950 (2011)
Low-grade inflammation in different tissues, including activation of the nuclear factor κB pathway in liver, is involved in metabolic disorders such as type 2 diabetes and cardiovascular diseases (CVDs). In this study, we investigated the relation b
Externí odkaz:
https://doaj.org/article/ea0280a294cd4217a1ff5480e6afc299
Autor:
Ok-Hee Kim, Geun-Hyung Kang, June Hur, Jinwook Lee, YunJae Jung, In-Sun Hong, Hookeun Lee, Seung-Yong Seo, Dae Ho Lee, Cheol Soon Lee, In-Kyu Lee, Susan Bonner-Weir, Jongsoon Lee, Young Joo Park, Hyeonjin Kim, Steven E. Shoelson, Byung-Chul Oh
Publikováno v:
Cell Death & Differentiation. 29:1423-1432
Apoptotic cells are rapidly engulfed and removed by phagocytes after displaying cell surface eat-me signals. Among many phospholipids, only phosphatidylserine (PS) is known to act as an eat-me signal on apoptotic cells. Using unbiased proteomics, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d801c7c5160645312bacce3cbe2e354
https://doi.org/10.1038/s41418-022-00931-2
https://doi.org/10.1038/s41418-022-00931-2
Regulation of diet-induced adipose tissue and systemic inflammation by salicylates and pioglitazone.
Autor:
Myung-Sunny Kim, Yasuhiko Yamamoto, Kyungjin Kim, Nozomu Kamei, Takeshi Shimada, Libin Liu, Kristin Moore, Ju Rang Woo, Steven E Shoelson, Jongsoon Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82847 (2013)
It is increasingly accepted that chronic inflammation participates in obesity-induced insulin resistance and type 2 diabetes (T2D). Salicylates and thiazolidinediones (TZDs) both have anti-inflammatory and anti-hyperglycemic properties. The present s
Externí odkaz:
https://doaj.org/article/73bca66bed504cc890c784fb544fd967
Publikováno v:
International Journal of Biological Macromolecules. 103:965-971
TBC1D4 (also known as AS160) is a Rab·GTPase-activating protein (RabGAP) which functions in insulin signaling. TBC1D4 is critical for translocation of glucose transporter 4 (GLUT4), from an inactive, intracellular, vesicle-bound site to the plasma m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cdad9ce0d1d7200fc9b84e45afb585
https://doi.org/10.1016/j.ijbiomac.2017.05.119
https://doi.org/10.1016/j.ijbiomac.2017.05.119
Autor:
Allison B. Goldfine, Thomas H. Hauser, Ninad Salastekar, Tanvi Desai, Steven E. Shoelson, Kristen Fowler, Stacey Joseph, Ernst J. Schaefer
Publikováno v:
Diabetes, Obesity and Metabolism. 19:1458-1462
To assess long-term efficacy and safety of salsalate to improve glycemia in persons with diabetes risk, who are overweight with statin-treated, stable coronary heart disease.Glycemic status was assessed in 192 persons without diabetes at baseline in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc451f9a99b5d6cab0e5ba054d8618b8
https://doi.org/10.1111/dom.12940
https://doi.org/10.1111/dom.12940
Autor:
Pawel A. Osmulski, Hanyu Liang, Katherine E. Fischer, Joseph M. Valentine, You Zhou, Steven E. Shoelson, Yi Chen, Arunabh Bhattacharya, Mengyao E. Li, Ning Zhang, Hung I. Chen, Michael E. Walsh, Holly Van Remmen, Yiqiang Zhang, Steven N. Austad, Maria Gaczynska, Nicolas Musi
Publikováno v:
Aging Cell
Summary Older adults universally suffer from sarcopenia and approximately 60–70% are diabetic or prediabetic. Nonetheless, the mechanisms underlying these aging‐related metabolic disorders are unknown. NFκB has been implicated in the pathogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee41e0b2af5d0ee1ff1192612151c3d9
http://europepmc.org/articles/PMC5506420
http://europepmc.org/articles/PMC5506420
Autor:
Alla B. Salmina, Steven E. Shoelson, Masahide Asano, Yasuko Kitao, Maria Gerasimenko, Natalia A. Malinovskaya, Hiroshi Yamamoto, Kisaburo Deguchi, Kazumi Furuhara, Osamu Hori, Olga Lopatina, Yasuhiko Yamamoto, Yasuhiko Hayashi, Yu Shimizu, Yulia K. Komleva, Haruhiro Higashida, Jing Zhong, Yoshitake Shiraishi, Katsuhiko Nishimori, Hisanori Goto, Tomoya Kamide, Mitsutoshi Nakada, Noriyuki Ozaki, Mingkun Liang, Ai Harashima, Yuya Eguchi, Shirin Akther, Teruko Yuhi, Akifumi Yoshikawa, Seiichi Munesue
Publikováno v:
Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-13 (2019)
Communications Biology, Vol 2, Iss 1, Pp 1-13 (2019)
金沢大学医薬保健研究域医学系
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal bonding behaviours. Mice lacking secreted oxcytocin (Oxt -/-, Cd38 -/-) or its receptor (Oxtr -/-) fail
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal bonding behaviours. Mice lacking secreted oxcytocin (Oxt -/-, Cd38 -/-) or its receptor (Oxtr -/-) fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e1101447c34f9b51b1d4bd4c80d339
http://europepmc.org/articles/PMC6389896
http://europepmc.org/articles/PMC6389896
Autor:
Robert L. Reddick, Steven E. Shoelson, Nicolas Musi, Mengyao E. Li, Ning Zhang, Joseph M. Valentine
Publikováno v:
J Gerontol A Biol Sci Med Sci
Nuclear factor (NF)κB is a transcription factor that controls immune and inflammatory signaling pathways. In skeletal muscle, NFκB has been implicated in the regulation of metabolic processes and tissue mass, yet its affects on mitochondrial functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f13f46b2cbde64976358eac1cdfcffb
https://europepmc.org/articles/PMC7328192/
https://europepmc.org/articles/PMC7328192/
Publikováno v:
Diabetes. 67
NFκB is a transcription factor that controls immune and inflammatory processes. In muscle, NFκB has been implicated in regulation of muscle mass/function, metabolism, and mitochondrial function. Yet, NFκB’s role in aging-related changes to skele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6163c7355302d3c25cde422c9549d10f
https://doi.org/10.2337/db18-1922-p
https://doi.org/10.2337/db18-1922-p
Publikováno v:
The Journal of clinical investigation. 127(1)
Obesity-related sub-acute chronic inflammation has been associated with incident type 2 diabetes and atherosclerotic cardiovascular disease. Inflammation is increasingly considered to be a pathologic mediator of these commonly co-occurring diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190196cae8c6c4b19b34cd357e829a35
https://pubmed.ncbi.nlm.nih.gov/28045401
https://pubmed.ncbi.nlm.nih.gov/28045401