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pro vyhledávání: '"Steven E. Seiler"'
Autor:
Eddie C.-K. Liu, Martin L. Ogletree, William A. Schumacher, Steven E. Seiler, Anne B. Stewart, Jeffrey S. Bostwick, Karen S. Hartl, Thomas E. Steinbacher
Publikováno v:
European Journal of Pharmacology. 570:167-174
The effect of inhibiting activated blood coagulation factor XIa was determined in rat models of thrombosis and hemostasis. BMS-262084 is an irreversible and selective small molecule inhibitor of factor XIa with an IC(50) of 2.8 nM against human facto