Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Steven E. Mckenzie"'
Autor:
Malika Aid, Kathryn E. Stephenson, Ai-ris Y. Collier, Joseph P. Nkolola, James V. Michael, Steven E. McKenzie, Dan H. Barouch
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Thrombosis with thrombocytopenia syndrome (TTS) is a rare but potentially severe adverse event following immunization with adenovirus vector-based COVID-19 vaccines such as Ad26.COV2.S (Janssen) and ChAdOx1 (AstraZeneca). However, no case of
Externí odkaz:
https://doaj.org/article/9e0279f50cd949b9be8538aa12037484
Autor:
Frederik Denorme, Nicole D. Armstrong, Michelle L. Stoller, Irina Portier, Emilia A. Tugolukova, Rikki M. Tanner, Emilie Montenont, Seema Bhatlekar, Mark Cody, John L. Rustad, Abigail Ajanel, Neal D. Tolley, Darian C. Murray, Julie L. Boyle, Marvin T. Nieman, Steven E. McKenzie, Christian Con Yost, Leslie A. Lange, Mary Cushman, Marguerite R. Irvin, Paul F. Bray, Robert A. Campbell
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
Protease-activated receptor 4 (PAR4) (gene F2RL3) harbors a functional dimorphism, rs773902 A/G (encoding Thr120/Ala120, respectively) and is associated with greater platelet aggregation. The A allele frequency is more common in Black individuals, an
Externí odkaz:
https://doaj.org/article/d092af6b93764c9897fa3db88dadf434
Autor:
Ruben Rhoades MD, MS, Zachary French MD, Amy Yang PharmD, RPh, Karen Walsh DHSc, MS, MBA, Douglass A. Drelich MD, Steven E. McKenzie MD, PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Persons with bleeding disorders (PwBD) are at high risk for bleeding with invasive procedures. However, the risk of bleeding in PwBD undergoing major surgery and outcomes of patients managed perioperatively at a hemophilia treatment center (HTC) are
Externí odkaz:
https://doaj.org/article/bddf0b1c93fb49919a09921d4368c5ab
Autor:
Xi Chen, Shuchi Gupta, Matthew Cooper, Daniel DeHelian, Xuefei Zhao, Meghna U. Naik, Jeremy G.T. Wurtzel, Timothy J. Stalker, Lawrence E. Goldfinger, Jeffrey Benovic, Lawrence F. Brass, Steven E. McKenzie, Ulhas P. Naik, Peisong Ma
Publikováno v:
Blood Advances, Vol 4, Iss 1, Pp 76-86 (2020)
Abstract: G protein–coupled receptors (GPCRs) mediate the majority of platelet activation in response to agonists. However, questions remain regarding the mechanisms that provide negative feedback toward activated GPCRs to limit platelet activation
Externí odkaz:
https://doaj.org/article/9286a5cfa8b840369f56985b7b2a876e
Autor:
Kaitlyn C. Dykes MD, BS, Cassandra A. Johnson BS, Jerald Z. Gong MD, MS, Steven E. McKenzie MD, PhD, Holleh D. Husseinzadeh MD, MSCE
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021)
Empiric management in suspected heparin-induced thrombocytopenia (HIT) is challenging due to imperfect prediction models, latency while awaiting test results and risks of empiric therapies. When there is high clinical suspicion for HIT, cessation of
Externí odkaz:
https://doaj.org/article/56048efea18f42748d5c41e4274db7e1
Autor:
John C. Kostyak, Benjamin R. Mauri, Carol Dangelmaier, Akruti Patel, Yuhang Zhou, Johannes A. Eble, Alexander Y. Tsygankov, Steven E. McKenzie, Satya P. Kunapuli
Publikováno v:
TH Open, Vol 02, Iss 04, Pp e411-e419 (2018)
Platelet activation is essential for hemostasis. Central to platelet activation are the signals transmitted through surface receptors such as glycoprotein VI, the protease-activated receptors, and C-type lectin-like receptor 2 (CLEC-2). CLEC-2 is a H
Externí odkaz:
https://doaj.org/article/eba57c87555643969e2802ebd988c4e3
Autor:
Angela Huynh, Donald M. Arnold, James V. Michael, Rumi Clare, James W. Smith, Mercy Daka, Monica Ianosi-Irimie, Steven E. McKenzie, John G. Kelton, Ishac Nazy
Publikováno v:
Blood Advances. 7:246-250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec52c596bf1548935980f4add6d2942
https://doi.org/10.1182/bloodadvances.2022007336
https://doi.org/10.1182/bloodadvances.2022007336
Autor:
Xuefei Zhao, Matthew Cooper, James V. Michael, Yanki Yarman, Aiden Baltz, J. Kurt Chuprun, Walter J. Koch, Steven E. McKenzie, Maurizio Tomaiuolo, Timothy J. Stalker, Li Zhu, Peisong Ma
Publikováno v:
Blood Advances. 6:4524-4536
The critical role of G protein–coupled receptor kinase 2 (GRK2) in regulating cardiac function has been well documented for >3 decades. Targeting GRK2 has therefore been extensively studied as a novel approach to treating cardiovascular disease. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ef9b82a722e4cfb7d4214e97bc9f21
https://doi.org/10.1182/bloodadvances.2022007007
https://doi.org/10.1182/bloodadvances.2022007007
Autor:
Joseph Dovidio, H.T. Massey, Jerald Z. Gong, J. Eduardo Rame, Lydia McDermott, Ron Leong, Ruben Rhoades, Shannon Barletti, Nawar N Al-Rawas, Brandi Thoma, Jason Kopenitz, Steven E. McKenzie
Publikováno v:
Thrombosis Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77d30b827ab0366f0a0db6beda1404e
https://doi.org/10.1016/j.thromres.2021.04.008
https://doi.org/10.1016/j.thromres.2021.04.008
Autor:
Tamam Bakchoul, Maria Therese Ahlen, Ishac Nazy, Ruchika Sharma, Karina Althaus, Steven E. McKenzie, Ulrich J. Sachs, Phil M. Choi, Rachael F. Grace, Donald M. Arnold
Publikováno v:
Journal of Thrombosis and Haemostasis
Vaccine administration is under way worldwide to combat the current COVID‐19 pandemic. The newly developed vaccines are highly effective with minimal adverse effects. Recently, the AstraZeneca ChadOx1 nCov‐19 vaccine has raised public alarm with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983bac6463e23b63d1f4bedcd1f5b39e
http://europepmc.org/articles/PMC8250233
http://europepmc.org/articles/PMC8250233