Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Steven E. Klohr"'
Publikováno v:
PDA journal of pharmaceutical science and technology. 70(1)
A feasibility study was conducted for a sensitive and robust dye immersion method for the measurement of container closure integrity of unopened prefilled syringes using fluorescence spectrophotometry as the detection method. A Varian Cary Eclipse sp
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 65:486-505
A leak test performed according to ASTM F2338-09 Standard Test Method for Nondestructive Detection of Leaks in Packages by Vacuum Decay Method was developed and validated for container-closure integrity verification of a lyophilized product in a pare
Autor:
Saul W. Fink, Kumar Penmetsa, Christopher D. Reddick, Gerald C. DiDonato, Brent Kleintop, Kevin J. Volk, Steven E. Klohr
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 23:831-839
The majority of chiral HPLC separations are performed in the normal-phase mode using alcohol-modified hexane mobile phases. Normal-phase chiral HPLC methods are not routinely coupled with electrosp...
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 20:115-128
A method has been developed for the real-time analysis of components in in vitro reactions by the on-line combination of microdialysis sampling (MD) with tandem mass spectrometry (MS/MS) and single stage mass spectrometry (MS). Apparatus and paramete
Autor:
Edward H. Kerns, Daniel R. Schroeder, John E. Leet, Kevin J. Volk, Steven E. Klohr, Ira E. Rosenberg, Mike S. Lee
Publikováno v:
Journal of Mass Spectrometry. 31:1253-1260
Structure identification strategies for kedarcidin chromophore are described using tandem mass spectrometry (MS/MS) and high-resolution MS techniques. The strategy involves dividing a large, complex natural product molecule into several smaller molec
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 14:1663-1674
A rapid and systemic strategy based on liquid chromatography/mass spectrometry (LC/MS) profiling and liquid chromatography/tandem mass spectrometry (LC/MS/MS) substructural techniques was utilized to elucidate the degradation products of butorphanol,
Autor:
Steven E. Klohr, Stella Huang, Richard A. Dalterio, Jingfang Qian-Cutrone, Li-Ping Chang, Susan E. Lowe, Dolores M. Pirnik, M. Alam, Kathleen F. Kadow, Robert Hugill
Publikováno v:
The Journal of Antibiotics. 49:990-997
During the screening of the natural products for their ability to inhibit the binding of REV (regulation of virion expression) protein to [33P] labeled RRE (REV responsive element) RNA, two novel fungal metabolites, harziphilone and fleephilone, were
Publikováno v:
The Journal of Antibiotics. 49:553-559
The novel antifungal agent ascosteroside (1) was isolated from cultured broth of Ascotricha amphitricha (ATCC 74237). The structure based on spectroscopic data was determined to be an alpha-linked glycoside of a lanostane-type triterpenoid.
Autor:
Pin-Fang Lin, Stella Huang, Kathleen F. Kadow, John J. Trimble, Steven E. Klohr, Hui Li, M. Alam, Jingfang Qian-Cutrone
Publikováno v:
Journal of Natural Products. 59:196-199
During the screening of natural products for their ability to inhibit the binding of HIV-REV protein to [33P]-labeled RRE RNA, one novel compound, niruriside (1), was isolated from the MeOH extract of the dried leaf of Phyllanthus niruri L. by bioass
Publikováno v:
Journal of Natural Products. 57:1656-1660