Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Steven E. Kauder"'
Autor:
Tracy C. Kuo, Amy Chen, Ons Harrabi, Jonathan T. Sockolosky, Anli Zhang, Emma Sangalang, Laura V. Doyle, Steven E. Kauder, Danielle Fontaine, Sangeetha Bollini, Bora Han, Yang-Xin Fu, Janet Sim, Jaume Pons, Hong I. Wan
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2020)
Abstract Background Signal regulatory protein α (SIRPα) is a myeloid-lineage inhibitory receptor that restricts innate immunity through engagement of its cell surface ligand CD47. Blockade of the CD47–SIRPα interaction synergizes with tumor-spec
Externí odkaz:
https://doaj.org/article/aafee68f22694b6fb3c27f80eac48cb0
Autor:
Steven E Kauder, Tracy C Kuo, Ons Harrabi, Amy Chen, Emma Sangalang, Laura Doyle, Sony S Rocha, Sangeetha Bollini, Bora Han, Janet Sim, Jaume Pons, Hong I Wan
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201832 (2018)
CD47 is a widely expressed cell surface protein that functions as an immune checkpoint in cancer. When expressed by tumor cells, CD47 can bind SIRPα on myeloid cells, leading to suppression of tumor cell phagocytosis and other innate immune function
Externí odkaz:
https://doaj.org/article/3ebc34039c37468dbf22b9ca99bbcb93
Autor:
Chen Amy Shaw-Ru, Anup Madan, Janet Sim, Ons Harrabi, Tracy C. Kuo, Hong Wan, Ardian S Wibowo, Shelley Izquierdo, Emma Sangalang, Darlene Pedersen, Josh Carter, Steven E. Kauder, Jonathan T. Sockolosky, Jaume Pons, Harriman William Don, Laura Doyle
Publikováno v:
mAbs
Targeting the CD47-signal-regulatory protein α (SIRPα) pathway represents a novel therapeutic approach to enhance anti-cancer immunity by promoting both innate and adaptive immune responses. Unlike CD47, which is expressed ubiquitously, SIRPα expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b6e62d7e10586ce646d15c3a63cebd
http://europepmc.org/articles/PMC6748616
http://europepmc.org/articles/PMC6748616
Autor:
Steven E Kauder, Lydia Santell, Elaine Mai, Lilyan Y Wright, Elizabeth Luis, Elsa N N'Diaye, Jeff Lutman, Navneet Ratti, Susan M Sa, Henry R Maun, Eric Stefanich, Lino C Gonzalez, Robert R Graham, Lauri Diehl, William A Faubion, Mary E Keir, Judy Young, Amitabha Chaudhuri, Robert A Lazarus, Jackson G Egen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83958 (2013)
Macrophage stimulating protein (MSP) is a serum growth factor that binds to and activates the receptor tyrosine kinase, Recepteur d'Origine Nantais (RON). A non-synonymous coding variant in MSP (689C) has been associated with genetic susceptibility t
Externí odkaz:
https://doaj.org/article/6b29382e11a343b58a0d4a762432fc8a
Publikováno v:
PLoS Pathogens, Vol 5, Iss 6, p e1000495 (2009)
Human immunodeficiency virus type 1 (HIV-1) persists in a latent state within resting CD4+ T cells of infected persons treated with highly active antiretroviral therapy (HAART). This reservoir must be eliminated for the clearance of infection. Using
Externí odkaz:
https://doaj.org/article/75319b213dc04f6c8349a78e1736507c
Autor:
Romina Riener, Scott Alan Mccauley, Jan Emmerich, Deepti Rokkam, Steven E. Kauder, Rene de Waal Malefyt, Rakesh Verma, Rob A. Kastelein, Sandro Vivona, Michael A Bauer, Martin Oft, Paul-Joseph Aspuria
Publikováno v:
Blood. 136:35-35
CAR T cell therapy has demonstrated remarkable clinical efficacy against relapsed and refractory hematological malignancies, such as B cell non-Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL) (Neelapu et al. NEJM, 2017; Schuster et al.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d3767dd92fc15ab449049010930ae4a
https://doi.org/10.1182/blood-2020-143483
https://doi.org/10.1182/blood-2020-143483
Autor:
Steven E. Kauder, Rob A. Kastelein, Michele Bauer, Jan Emmerich, Patrick J. Lupardus, Romina Riener, Rene De Waal Malefyte, Deepti Rokkam, Paul-Joseph Aspuria, Sandro Vivona, Scott Alan Mccauley, Martin Oft, Navneet Ratti
Publikováno v:
Cancer Research. 80:3252-3252
CAR T cell therapy has demonstrated remarkable clinical efficacy against relapsed and refractory hematological malignancies, such as B cell non-Hodgkin lymphoma (NHL) and acute lymphoblastic leukemia (ALL). Despite these advances, prominent barriers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::836f173deccaf826eb308893cd0b7c5b
https://doi.org/10.1158/1538-7445.am2020-3252
https://doi.org/10.1158/1538-7445.am2020-3252
Autor:
Hong I. Wan, Emma Sangalang, Tracy C. Kuo, Ons Harrabi, Laura Doyle, Janet Sim, Jaume Pons, Bora Han, Amy Y. Chen, Sangeetha Bollini, Sony S. Rocha, Steven E. Kauder
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201832 (2018)
PLoS ONE
PLoS ONE
CD47 is a widely expressed cell surface protein that functions as an immune checkpoint in cancer. When expressed by tumor cells, CD47 can bind SIRPα on myeloid cells, leading to suppression of tumor cell phagocytosis and other innate immune function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0084e4ed70449fa13ce8d6b32e9f2bad
http://europepmc.org/articles/PMC6104973?pdf=render
http://europepmc.org/articles/PMC6104973?pdf=render
Autor:
Sangeetha Bollini, Jaume Pons, Laura V. Doyle, Hong I. Wan, Ons Harrabi, Tracy C. Kuo, Steven E. Kauder, Emma Sangalang, Amy Y. Chen, Bora Han, Janet Sim
Publikováno v:
Cancer Research. 79:562-562
Targeting the CD47-SIRPα myeloid checkpoint pathway represents a novel therapeutic approach to enhance anti-cancer immunity. CD47 is a widely expressed cell surface protein that functions as a marker of self. Signal regulatory protein-α (SIRPα) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf75345ae85a06dcfa261d130876ab91
https://doi.org/10.1158/1538-7445.am2019-562
https://doi.org/10.1158/1538-7445.am2019-562
Autor:
Paul J. Wolters, Jasleen Kukreja, Satyajit K Karnik, Daryle Depianto, Alexander R. Abbas, Harold R. Collard, Sabyasachi Biswas, Steven E. Kauder, Connie Ha, Elsa N N'Diaye, Guiquan Jia, Zora Modrusan, Patrick Caplazi, Michael A. Matthay, Sanjay Chandriani, Jackson G. Egen, Joseph R. Arron
Publikováno v:
DePianto, DJ; Chandriani, S; Abbas, AR; Jia, G; N'Diaye, EN; Caplazi, P; et al.(2015). Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis. Thorax, 70(1), 48-56. doi: 10.1136/thoraxjnl-2013-204596. UCSF: Retrieved from: http://www.escholarship.org/uc/item/20x7s6cx
Thorax, vol 70, iss 1
Thorax, vol 70, iss 1
© 2014, BMJ Publishing Group. All rights reserved. Background: There is microscopic spatial and temporal heterogeneity of pathological changes in idiopathic pulmonary fibrosis (IPF) lung tissue, which may relate to heterogeneity in pathophysiologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb45eac670e916b08f9cb61cc7a1055
http://www.escholarship.org/uc/item/20x7s6cx
http://www.escholarship.org/uc/item/20x7s6cx
