Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Steven E. Freeman"'
Autor:
Betsy M. Sutherland, John C. Sutherland, Steven E. Freeman, Richard W. Gange, Daniel J. Maytum, Haim Hacham
Publikováno v:
Photochemistry and Photobiology. 53:559-563
— Ultraviolet radiation produces erythema in human skin, and damages the DNA of living cells in skin. Previous work showed that broad-band UV-B (290–320 nm) radiation produced higher levels of cyclobutyl pyrimidine dimers in DNA of individuals wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2475dbe6affbf567f760277157dc4e0b
https://doi.org/10.1111/j.1751-1097.1991.tb03671.x
https://doi.org/10.1111/j.1751-1097.1991.tb03671.x
Autor:
Daniel J. Maytum, Steven E. Freeman, Haim Hacham, Richard W. Gange, Betsy M. Sutherland, John C. Sutherland
Publikováno v:
Photochemistry and Photobiology. 52:893-896
A previous report [Freeman et al. (1986) Photochem. Photobiol. 43S, 93S] indicated that irradiation of human skin in situ with 385 or 405 nm radiation produced detectable levels of pyrimidine dimers in DNA. Since these wavelengths are absorbed poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae6b794c35f4c5ce2699d68b87e513d3
https://doi.org/10.1111/j.1751-1097.1990.tb08698.x
https://doi.org/10.1111/j.1751-1097.1990.tb08698.x
Publikováno v:
Journal of Investigative Dermatology. 96:898-902
Ultraviolet excimer lasers are being considered for use in a variety of refractive and therapeutic procedures, the long-term biologic consequences of which are unknown. The effect of sublethal doses of 193-nm laser radiation on cellular DNA was exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7811af34be08b7e338df00964391a6
https://doi.org/10.1111/1523-1747.ep12475412
https://doi.org/10.1111/1523-1747.ep12475412
Autor:
Bryan D. Thompson, Steven E. Freeman
Publikováno v:
Analytical Biochemistry. 186:222-228
We have compared video and photographic methods for calculating the number of ultraviolet radiation (uv)-induced pyrimidine dimers in DNA from the bacteriophage T7 exposed to uv (0 to 800 J/m2) from an FS40 sunlamp. DNA was incubated with a pyrimidin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44629838cc13d3a5d2fcc6d9436a0573
https://doi.org/10.1016/0003-2697(90)90070-p
https://doi.org/10.1016/0003-2697(90)90070-p
Publikováno v:
The Journal of investigative dermatology. 95(5)
One prominent lesion induced in DNA by ultraviolet (UV) radiation is the cyclobutyl pyrimidine dimer formed between adjacent pyrimidines on the same DNA strand. We investigated whether people who have developed basal cell carcinoma on sun-exposed ski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03afbf525c2fc078bf10a7cf4cfe3aea
https://pubmed.ncbi.nlm.nih.gov/2230212
https://pubmed.ncbi.nlm.nih.gov/2230212
Autor:
Steven E. Freeman, Sharon L. Ryan
Publikováno v:
Mutation research. 235(3)
An action spectrum for the induction of pyrimidine dimers in human peripheral lymphocytes was determined between 254 and 405 nm. The presence of pyrimidine dimers was determined as UV-induced lesions that were sensitive to the dimer-specific endonucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed69be0aebf0345509340befcf61259
https://pubmed.ncbi.nlm.nih.gov/2342505
https://pubmed.ncbi.nlm.nih.gov/2342505
Publikováno v:
Electrophoresis. 11(5)
The separation of DNA by gel electrophoresis provides a rapid method for determining size distributions of DNA in solution. Densitometric scanning of photographs of gels has been the standard method of analysis of agarose gels. However, analysis of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780b577a75ca2cec511cdcc02f16bed1
https://pubmed.ncbi.nlm.nih.gov/2364929
https://pubmed.ncbi.nlm.nih.gov/2364929
Autor:
Steven E. Freeman
Publikováno v:
DNA Damage and Repair in Human Tissues ISBN: 9781461279037
Ultraviolet radiation (UV) from sunlight is the major etiologic factor in the genesis of skin cancer. For squamous and basal cell carcinoma, the correlation of rates of incidence with latitude and, presumbably, solar exposure (Scotto, 1986), occurenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7684b9253abfbdfb571930b0792310a
https://doi.org/10.1007/978-1-4613-0637-5_9
https://doi.org/10.1007/978-1-4613-0637-5_9
Evaluation of densitometry data using interactive computer graphics: Application to DNA agarose gels
Autor:
Bryan D. Thompson, Steven E. Freeman
Publikováno v:
International Journal of Bio-Medical Computing. 22:121-133
A method of analyzing DNA agarose gels using interactive computer graphics is described. After electrophoresis in an alkaline agarose gel, DNA is neutralized, stained with ethidium bromide and excited with ultraviolet radiation. The resulting fluores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4564280678bbfe781115b8e7a179340f
https://doi.org/10.1016/0020-7101(88)90048-7
https://doi.org/10.1016/0020-7101(88)90048-7
Autor:
Betsy M. Sutherland, Denise C. Monteleone, John C. Sutherland, Steven E. Freeman, Richard B. Setlow, Anthony D. Blackett
Publikováno v:
Analytical Biochemistry. 158:119-129
We have developed an alkaline agarose gel method for quantitating single strand breaks in nanogram quantities of nonradioactive DNA. After electrophoresis together with molecular length standards, the DNA is neutralized, stained with ethidium bromide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09411601ef14920bc8a6e977bd3359ea
https://doi.org/10.1016/0003-2697(86)90599-3
https://doi.org/10.1016/0003-2697(86)90599-3