Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Steven E. Dunlap"'
Autor:
Edward W. Conder, Roger Ryan Rothhaar, Mark A. LaPack, Jared W. Fennell, Timothy M. Braden, R. Brian Scherer, Jeffrey Czarnik, Jeffrey Thomas Vicenzi, Mark D. Argentine, Jeffrey G. Wei, John Arnold Werner, Robert T. Roginski, Schmid Christopher Randall, Steven E. Dunlap
Publikováno v:
Organic Process Research & Development. 13:131-143
The impact of several new technologies on the development of a manufacturing process for LY518674 is described. Extensive use of process analytical technology (PAT) throughout development, both at laboratory and pilot-plant scale, enabled data-rich e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e597de403aa8d91135c9994bdea3f035
https://doi.org/10.1021/op8002486
https://doi.org/10.1021/op8002486
Autor:
Stephen W. Kaldor, Leonard L. Winneroski, Michael A. Staszak, James E. Fritz, Scott Alan Frank, Michael E. LeTourneau, Jeffrey A. Ward, Margaret M. Faul, Steven E. Dunlap, John Arnold Werner, Huff Bret Eugene
Publikováno v:
Tetrahedron. 53:8085-8104
The synthesis of 2′,3′-dideoxy-3′-hydroxymethylcytidine 1 was accomplished using two different approaches. First, uridine and cytidine were used to prepare the key intermediate epoxides 15 and 31 which were opened with cyanide, deoxygenated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5687138dc3bc9a49bed9d6c2867d3a68
https://doi.org/10.1016/s0040-4020(97)00500-0
https://doi.org/10.1016/s0040-4020(97)00500-0
Autor:
John Arnold Werner, Stephen W. Kaldor, Steven E. Dunlap, Leonard L. Winneroski, Michael A. Staszak, Margaret M. Faul, James E. Fritz, Huff Bret Eugene, Michael E. LeTourneau, Jeffrey A. Ward, Scott Alan Frank
Publikováno v:
ChemInform. 28
The synthesis of 2′,3′-dideoxy-3′-hydroxymethylcytidine 1 was accomplished using two different approaches. First, uridine and cytidine were used to prepare the key intermediate epoxides 15 and 31 which were opened with cyanide, deoxygenated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::509387b952d91c85c8a6ae776e39759a
https://doi.org/10.1002/chin.199741276
https://doi.org/10.1002/chin.199741276
Autor:
Mark D. Argentine, Timothy M. Braden, Jeffrey Czarnik, Edward W. Conder, Steven E. Dunlap, Jared W. Fennell, Mark A. LaPack, Roger R. Rothhaar, R. Brian Scherer, Christopher R. Schmid, Jeffrey T. Vicenzi, Jeffrey G. Wei, John A. Werner, Robert T. Roginski
Publikováno v:
Organic Process Research & Development; Mar2009, Vol. 13 Issue 2, p131-143, 13p
Publikováno v:
Helvetica Chimica Acta. 72:1301-1310
The preparation of optically active 1-amino-2-(hydroxymethyl)cyclopropanecarboxylic acid has been achieved by a route involving cycloalkylation of dimethyl malonate with epichlorohydrin and subsequent Hofmann rearrangement. The reaction of epichloroh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fe1d119f1431717f0a957e7ccfdb5e3
https://doi.org/10.1002/hlca.19890720618
https://doi.org/10.1002/hlca.19890720618
Publikováno v:
ChemInform. 20
The preparation of optically active 1-amino-2-(hydroxymethyl)cyclopropanecarboxylic acid has been achieved by a route involving cycloalkylation of dimethyl malonate with epichlorohydrin and subsequent Hofmann rearrangement. The reaction of epichloroh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9efa791055f737bbd9cf36fc7728acc8
https://doi.org/10.1002/chin.198950309
https://doi.org/10.1002/chin.198950309