Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Steven Dow"'
Autor:
Dylan T. Ammons, Leone S. Hopkins, Kathryn E. Cronise, Jade Kurihara, Daniel P. Regan, Steven Dow
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Osteosarcoma (OS) is a heterogeneous, aggressive malignancy of the bone that disproportionally affects children and adolescents. Therapeutic interventions for OS are limited, which is in part due to the complex tumor microenvironment (TME).
Externí odkaz:
https://doaj.org/article/a117ed88309245d08834c3feb15089c6
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Chronic rhinitis (CR) is a frustrating clinical syndrome in dogs and our understanding of the disease pathogenesis in is limited. Increasingly, host–microbe interactions are considered key drives of clinical disease in sites of persistent mucosal i
Externí odkaz:
https://doaj.org/article/14e2931fa48c477fbe82188f541b93f4
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Chronic inflammatory enteropathy (CIE) is a common condition in dogs causing recurrent or persistent gastrointestinal clinical signs. Pathogenesis is thought to involve intestinal mucosal inflammatory infiltrates, but histopathological evaluation of
Externí odkaz:
https://doaj.org/article/b4232417c9034365bc78b27739f9c7ca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The canine spontaneous cancer model is increasingly utilized to evaluate new combined cancer immunotherapy approaches. While the major leukocyte subsets and phenotypes are closely related in dogs and humans, the functionality of T cells and
Externí odkaz:
https://doaj.org/article/3969c80af0d14b6d90583a6b47a5ba86
Autor:
Laurel B. Darragh, Jacob Gadwa, Tiffany T. Pham, Benjamin Van Court, Brooke Neupert, Nicholas A. Olimpo, Khoa Nguyen, Diemmy Nguyen, Michael W. Knitz, Maureen Hoen, Sophia Corbo, Molishree Joshi, Yonghua Zhuang, Maria Amann, Xiao-Jing Wang, Steven Dow, Ross M. Kedl, Von Samedi, Mary-Keara Boss, Sana D. Karam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/56d3e7c7ade74d0a8371f2100dd57477
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Cellular senescence, a condition where cells undergo arrest and can assume an inflammatory phenotype, has been associated with initiation and perpetuation of inflammation driving multiple disease processes in rodent models and humans. Senescent cells
Externí odkaz:
https://doaj.org/article/6edd8ebef20045dca7e8a8063428ef5c
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2322-2333 (2023)
Abstract Background Diet may induce clinical remission in dogs with chronic enteropathy (CE). Elemental diets (EDs), providing protein as amino acids, modulate intestinal immunity and microbiome in rodents and humans. Hypothesis Evaluate the impact o
Externí odkaz:
https://doaj.org/article/841a11e1781c47ee9787b84d5c83de5b
Publikováno v:
Pathogens, Vol 13, Iss 7, p 602 (2024)
Background: Effective immunotherapeutic agents for use in cats are needed to aid in the management of intractable viral diseases, including feline infectious peritonitis (FIP) infection. The objectives of this study were to compare two different immu
Externí odkaz:
https://doaj.org/article/5d362a8007ef4d04ad2795e2dfad1195
Autor:
Brittany B Martabano, Steven Dow, Lyndah Chow, Margaret M V Williams, Maura K Mack, Rebecca Bellone, Kathryn L Wotman
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297366 (2024)
ObjectiveTo determine the safety and efficacy of perilesional human recombinant interferon alpha-2b (IFNα2b) for treatment of periocular squamous cell carcinoma (PSCC) in horses.Animals studiedEleven horses (12 eyes) with PSCC were enrolled in this
Externí odkaz:
https://doaj.org/article/a40d608caf8242d7b046e27e99f9c5ee
Publikováno v:
Veterinary Sciences, Vol 11, Iss 4, p 167 (2024)
Ocular surface squamous neoplasia (OSSN) represents the most common conjunctival tumor in horses and frequently results in vision loss and surgical removal of the affected globe. Multiple etiologic factors have been identified as contributing to OSSN
Externí odkaz:
https://doaj.org/article/53a27f4ddb5744159a1fb8eeeb793eb7