Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Steven De Gieter"'
Autor:
Steven De Gieter, Casey I Gallagher, Eveline Wijckmans, Diletta Pasini, Chris Ulens, Rouslan G Efremov
Publikováno v:
eLife, Vol 12 (2023)
Cys-loop receptors or pentameric ligand-gated ion channels are mediators of electrochemical signaling throughout the animal kingdom. Because of their critical function in neurotransmission and high potential as drug targets, Cys-loop receptors from h
Externí odkaz:
https://doaj.org/article/cb456e98491945be9edc90399c12c86b
Autor:
Remy Loris, Valentina Zorzini, Steven De Gieter, Abel Garcia-Pino, San Hadži, Yann G.-J. Sterckx, Sarah Haesaerts
Publikováno v:
Protein Expression and Purification. 108:30-40
Toxin-antitoxin (TA) modules are stress response elements that are ubiquitous in the genomes of bacteria and archaea. Production and subsequent purification of individual TA proteins is anything but straightforward as over-expression of the toxin gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914225272b4ddccf354fab71295bb7fe
https://doi.org/10.1016/j.pep.2015.01.001
https://doi.org/10.1016/j.pep.2015.01.001
Autor:
Steven De Gieter, Olivier Zwaenepoel, Kaat Durinck, Jan Gettemans, Franki Speleman, Remy Loris, Adriaan Verhelle, Jonas Bethuyne, Gholamreza Hassanzadeh-Ghassabeh, Abel Garcia-Pino
Publikováno v:
Nucleic Acids Research
NUCLEIC ACIDS RESEARCH
Nucleic acids research, 42 (20
NUCLEIC ACIDS RESEARCH
Nucleic acids research, 42 (20
The p53 transcription factor plays an important role in genome integrity. To perform this task, p53 regulates the transcription of genes promoting various cellular outcomes including cell cycle arrest, apoptosis or senescence. The precise regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacc0a02bf67ea508a9037505c7f91fe
http://europepmc.org/articles/PMC4227789
http://europepmc.org/articles/PMC4227789
Autor:
Steven De Gieter, Remy Loris, Henri De Greve, Abel Garcia-Pino, Ariel Talavera, Rouslan G. Efremov
Publikováno v:
Nature chemical biology. 12(7)
Conditional cooperativity is a common mechanism involved in transcriptional regulation of prokaryotic type II toxin-antitoxin operons and is intricately related to bacterial persistence. It allows the toxin component of a toxin-antitoxin module to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa0f10973b77d71195b95b6b1133fd8
https://pubmed.ncbi.nlm.nih.gov/27159580
https://pubmed.ncbi.nlm.nih.gov/27159580
Autor:
Abel Garcia-Pino, Sarah Haesaerts, Frank Sobott, Annika Butterer, Henri De Greve, Albert Konijnenberg, Remy Loris, Steven De Gieter, Ariel Talavera
Publikováno v:
Journal of biological chemistry
The Journal of biological chemistry, 289 (49
The Journal of biological chemistry, 289 (49
The toxin Doc from the phd/doc toxin-antitoxin module targets the cellular translation machinery and is inhibited by its antitoxin partner Phd. Here we show that Phd also functions as a chaperone, keeping Doc in an active, correctly folded conformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e06e6f9fc9860c3d606c847e41a7f146
https://hdl.handle.net/10067/1227440151162165141
https://hdl.handle.net/10067/1227440151162165141
Autor:
Nikolay Zenkin, Steven De Gieter, Daniel Castro-Roa, Abel Garcia-Pino, Nico A. J. van Nuland, Remy Loris
Publikováno v:
Nature chemical biology
Nature Chemical Biology 9(12), 811-817 (2013). doi:10.1038/nchembio.1364
Vrije Universiteit Brussel
Nature Chemical Biology 9(12), 811-817 (2013). doi:10.1038/nchembio.1364
Vrije Universiteit Brussel
Nature Chemical Biology 9(12), 811 - 817 (2013). doi:10.1038/nchembio.1364
Fic proteins are ubiquitous in all of the domains of life and have critical roles in multiple cellular processes through AMPylation of (transfer of AMP to) target protein
Fic proteins are ubiquitous in all of the domains of life and have critical roles in multiple cellular processes through AMPylation of (transfer of AMP to) target protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a6be943caf9cf8682516eeb718c89c
http://europepmc.org/articles/PMC3836179
http://europepmc.org/articles/PMC3836179
Publikováno v:
Biomolecular NMR assignments. 8(1)
Toxin-antitoxin (TA) modules in bacteria are involved in pathogenesis, antibiotic stress response, persister formation and programmed cell death. The toxin Doc, from the phd/doc module, blocks protein synthesis by targeting the translation machinery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1eb61ba06fd1044f81c5a6e038397c91
https://pubmed.ncbi.nlm.nih.gov/23420131
https://pubmed.ncbi.nlm.nih.gov/23420131
Autor:
Yann Sterckx, STEVEN DE GIETER, Valentina Zorzini, San Hadzi, Sarah Haesaerts, Remy Loris, Abel Garcia Pino
Publikováno v:
Vrije Universiteit Brussel
Toxin-antitoxin (TA) modules are stress response elements that are ubiquitous in the genomes of bacteria and archaea. Production and subsequent purification of individual TA proteins is anything but straightforward as over-expression of the toxin gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::44c4ee0be60449fdec0ad036f9670a85
https://researchportal.vub.be/en/publications/b9c42f46-4896-4123-a1de-83390bc2d78a
https://researchportal.vub.be/en/publications/b9c42f46-4896-4123-a1de-83390bc2d78a
Publikováno v:
Vrije Universiteit Brussel
Toxin-antitoxin (TA) modules in bacteria are involved in pathogenesis, antibiotic stress response, persister formation and programmed cell death. The toxin Doc, from the phd/doc module, blocks protein synthesis by targeting the translation machinery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8569a5e10f178f620cf589b36b44a8de
https://researchportal.vub.be/en/publications/e82f9b44-1ebb-49e5-ac5a-8808826cfd72
https://researchportal.vub.be/en/publications/e82f9b44-1ebb-49e5-ac5a-8808826cfd72