Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Steven D. Burke"'
Publikováno v:
The Journal of Organic Chemistry. 80:204-216
Four different Rh-catalyzed asymmetric hydroformylation (AHF) tandem reactions have been developed in the context of the total syntheses of (+)-patulolide C, (-)-pyrenophorol, (+)-decarestrictine L, and (+)-Prelog-Djerassi lactone. A total synthesis
Autor:
Robert J. Hamers, Jamie N. Wheeler, Xin Chen, Steven D. Burke, Marco D. Torelli, Michelle C. Benson, Joel A. Pedersen, Joseph C. Yeager, Lee M. Bishop
Publikováno v:
Langmuir. 28:1322-1329
Citric acid is a widely used surface-modifying ligand for growth and processing of a variety of nanoparticles; however, the inability to easily prepare derivatives of this molecule has restricted the development of versatile chemistries for nanoparti
Publikováno v:
The Journal of Organic Chemistry. 73:8452-8457
The synthesis of didemniserinolipid B utilizing a ketalization/ring-closing metathesis (K/RCM) strategy is described. In the course of this work, a novel 2-allyl-4-fluorophenyl auxiliary for relay ring-closing metathesis (RRCM) was developed, which i
Publikováno v:
Organic Letters. 8:5637-5640
A series of six 2,5-disubstituted adjacent bis(tetrahydrofuran) stereoisomers with trans/erythro/cis, trans/threo/trans, or cis/threo/cis relative stereochemistry have been synthesized from known dihydroxycyclooctenes via ring opening/cross metathesi
Autor:
Qian Zhao, Steven D. Burke, Ronald T. Raines, Eric S Benedict, Andrew J Hawk, Jia-Cherng Horng
Publikováno v:
Organic Letters. 8:4735-4738
[structure: see text] Three strands of natural collagen are linked by covalent bonds prior to their folding into a triple helix. We report on a synthetic collagen in which the strands are pendent on a rigid macrocyclic scaffold of C(3) symmetry. The
Publikováno v:
The Journal of Organic Chemistry. 70:9382-9398
[Reaction: see text]. Two efficient routes to the C1-C22 subunit of halichondrin B are described. The cage ketal 7, which contains 11 asymmetric centers embedded within the ABCDEF-ring framework, was assembled from (+)-conduritol E (27) in 18 steps a
A Catalytic Enantioselective Hetero Diels−Alder Approach to the C20−C32 Segment of the Phorboxazoles
Publikováno v:
The Journal of Organic Chemistry. 70:3757-3760
[reaction: see text] An efficient synthesis of the C20-C32 segment of the phorboxazoles has been achieved using an enantioselective hetero Diels-Alder reaction catalyzed by Jacobsen's Cr(III) amino indanol Schiff base catalyst.
Publikováno v:
Organic Letters. 7:737-740
The C22-C34 portion (2) of halichondrin B was synthesized from meso-symmetric bis-silyl protected cyclopentenediol (7) in 20 steps and 7% overall yield. This was accomplished through a two-directional synthesis/terminus differentiation strategy that
Publikováno v:
Organic Letters. 6:4045-4048
[reaction: see text] Synthesis of the northern hemisphere (C1-C16) of bryostatin 1, a potent anticancer agent, has been accomplished in 14 steps and 11% overall yield via desymmetrization by ketalization/ring-closing metathesis. A 2,9-dioxabicyclo[3.
Publikováno v:
The Journal of Organic Chemistry. 69:4534-4537
An efficient synthesis of Hale and co-workers' C17-C27 bryostatin southern hemisphere intermediate has been accomplished in six steps and 33% overall yield from (R)-2-(benzyloxy)propanal. The synthesis features a one-pot DIBALH/HWE ester homologation