Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Steven D Stockton"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e49789 (2012)
The diversity of receptor signaling is increased by receptor heteromerization leading to dynamic regulation of receptor function. While a number of studies have demonstrated that family A G-protein-coupled receptors are capable of forming heteromers
Externí odkaz:
https://doaj.org/article/c12a12522d2b48d7ac6e489e58826952
Autor:
Noura S Abul-Husn, Suresh P Annangudi, Avi Ma'ayan, Dinah L Ramos-Ortolaza, Steven D Stockton, Ivone Gomes, Jonathan V Sweedler, Lakshmi A Devi
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25535 (2011)
Opiates produce significant and persistent changes in synaptic transmission; knowledge of the proteins involved in these changes may help to understand the molecular mechanisms underlying opiate dependence. Using an integrated quantitative proteomics
Externí odkaz:
https://doaj.org/article/89107089705243909dd4da0e1e7168a3
Autor:
Fatma S. Genc, Christopher D. Dwyer, David E. Rosow, Steven D. Stockton Jr, VyVy N. Young, Clark A. Rosen
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 4, Pp 661-667 (2021)
Abstract Objectives Review abstracts presented at the Combined Otolaryngology Society Meeting (COSM) to determine subsequent publication and identify abstract features predictive of publication in high impact journals. Methods A selection of abstract
Externí odkaz:
https://doaj.org/article/ef00c09ec28e4b45ad93a894a063cafe
Autor:
Steven D. Stockton, David E. Rosow, Fatma S. Genc, VyVy N. Young, Clark A. Rosen, Christopher D. Dwyer
Publikováno v:
Laryngoscope investigative otolaryngology, vol 6, iss 4
Laryngoscope Investigative Otolaryngology
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 4, Pp 661-667 (2021)
Laryngoscope Investigative Otolaryngology
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 4, Pp 661-667 (2021)
Objectives Review abstracts presented at the Combined Otolaryngology Society Meeting (COSM) to determine subsequent publication and identify abstract features predictive of publication in high impact journals. Methods A selection of abstracts accepte
Autor:
Jose A. Morón, Avi Ma'ayan, Steven D. Stockton, Lakshmi A. Devi, Hong Li, Matthew R. Jones, Lucía Hipólito, Tong Liu, Ivone Gomes, Chandrakala Moraje
Publikováno v:
Molecular & Cellular Proteomics. 14:2564-2576
Despite its efficacy, the use of morphine for the treatment of chronic pain remains limited because of the rapid development of tolerance, dependence and ultimately addiction. These undesired effects are thought to be because of alterations in synapt
Autor:
Lakshmi A. Devi, Steven D. Stockton
Publikováno v:
Drug and Alcohol Dependence. 121:167-172
Morphine and other opiates are among the most widely prescribed and clinically useful medications for the treatment of chronic pain. However, the applicability of these compounds has been severely hampered by the rapid development of tolerance and ph
Publikováno v:
Brain Structure and Function. 214:161-179
Neurofibrillary tangles (NFTs) are composed of insoluble, hyperphosphorylated aggregates of the microtubule-associated protein tau and are present in various neurodegenerative diseases, including Alzheimer’s disease (AD). To investigate how tau aff
Autor:
Steven D. Stockton, Patrick R. Hof, Jessica J. Walsh, Sam Gandy, Dara L. Dickstein, Hannah Brautigam
Publikováno v:
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine. 77:82-102
Recent findings indicate that vascular risk factors and neurovascular dysfunction play integral roles in the pathogenesis of Alzheimer's disease. In addition to aging, the most common risk factors for Alzheimer's disease are apolipoprotein e4 allele,
Neuropeptides mediate their effects by binding and activating receptors that are responsible for converting these extracellular stimuli into intracellular responses. Most neuropeptides interact with G protein-coupled receptors that transduce the sign
Autor:
Steven D. Stockton, Lakshmi A. Devi
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 39(1)
Morphine is a classic analgesic for the treatment of chronic pain. However, its repeated use is known to produce tolerance, physical dependence, and addiction; these properties limit its long-term therapeutic use and this has led to a quest for thera