Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Steven D Forsythe"'
1
Akademický článek
Multifaceted modeling of small intestinal neuroendocrine tumors
Autor: Stephen Gabriel Andrews, Steven D Forsythe, James P Madigan, Samira Mercedes Sadowski
Publikováno v: Endocrine Oncology, Vol 4, Iss 1, Pp 1-13 (2024)
Small intestinal neuroendocrine tumors, siNETs, are a group of rare cancers that arise from neuroendocrine cells in the lining of the jejunum and ileum, which are either classified as tumors, siNETs, or small intestinal neuroendocrine carcinomas, siN
Externí odkaz: https://doaj.org/article/7184105602e04de4aafff8bcc3be33ef
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2
Akademický článek
Cisplatin exhibits superiority over MMC as a perfusion agent in a peritoneal mesothelioma patient specific organoid HIPEC platform
Autor: Steven D. Forsythe, Richard A. Erali, Nicholas Edenhoffer, William Meeker, Nadeem Wajih, Cecilia R. Schaaf, Preston Laney, Cristian D. Vanezuela, Wencheng Li, Edward A. Levine, Shay Soker, Konstantinos I. Votanopoulos
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Peritoneal mesothelioma (PM) is a rare malignancy with poor prognosis, representing about 10–15% of all mesothelioma cases. Herein we apply PM patient-derived tumor organoids (PTOs) in elucidating personalized HIPEC responses to bypass rar
Externí odkaz: https://doaj.org/article/b06ce63a27604f8892e9538a0600cbd8
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3
Akademický článek
Application of immune enhanced organoids in modeling personalized Merkel cell carcinoma research
Autor: Steven D. Forsythe, Richard A. Erali, Preston Laney, Hemamylammal Sivakumar, Wencheng Li, Aleksander Skardal, Shay Soker, Konstantinos I. Votanopoulos
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Merkel cell carcinoma (MCC) is a rare neuroendocrine cutaneous cancer, with incidence of less than 1/100,000, low survival rates and variable response to chemotherapy or immunotherapy. Herein we explore the application of patient tumor organ
Externí odkaz: https://doaj.org/article/b1099e5798d44799b77029561bf17af0
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6
Long-Term Survival in Patients Treated with Cytoreduction and Heated Intraperitoneal Chemotherapy for Peritoneal Mesothelioma at a Single High-Volume Center
Autor: Cristian D. Valenzuela, Ian B. Solsky, Richard A. Erali, Steven D. Forsythe, Christopher W. Mangieri, Bigyan B. Mainali, Gregory Russell, Kathleen C. Perry, Konstantinos I. Votanopoulos, Perry Shen, Edward A. Levine
Publikováno v: Ann Surg Oncol
BACKGROUND. Malignant peritoneal mesothelioma (MPM) is a rare diagnosis with a dismal prognosis if untreated. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is shown to significantly improve survival. Our institution
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db5f7114b24632004d53643d2f3f11f
https://europepmc.org/articles/PMC10249750/
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7
Akademický článek
Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids
Autor: Steven D. Forsythe, Mahesh Devarasetty, Thomas Shupe, Colin Bishop, Anthony Atala, Shay Soker, Aleksander Skardal
Publikováno v: Frontiers in Public Health, Vol 6 (2018)
IntroductionEnvironmental toxins, such as lead and other heavy metals, pesticides, and other compounds, represent a significant health concern within the USA and around the world. Even in the twenty-first century, a plethora of cities and towns in th
Externí odkaz: https://doaj.org/article/5ddc06c4e0464bd1b134920c2b7921d2
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