Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Steven D Crowley"'
Autor:
Shintaro Ide, Yoshihiko Kobayashi, Kana Ide, Sarah A Strausser, Koki Abe, Savannah Herbek, Lori L O'Brien, Steven D Crowley, Laura Barisoni, Aleksandra Tata, Purushothama Rao Tata, Tomokazu Souma
Publikováno v:
eLife, Vol 10 (2021)
Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in maladaptive renal repair in mice and humans. Using single-cell transcriptomic and mouse genetic appro
Externí odkaz:
https://doaj.org/article/00dbe0c73bae414ca6bbc0e4be36568e
Autor:
Shintaro Ide, Yasuhito Yahara, Yoshihiko Kobayashi, Sarah A Strausser, Kana Ide, Anisha Watwe, Shengjie Xu-Vanpala, Jamie R Privratsky, Steven D Crowley, Mari L Shinohara, Benjamin A Alman, Tomokazu Souma
Publikováno v:
eLife, Vol 9 (2020)
Renal macrophages represent a highly heterogeneous and specialized population of myeloid cells with mixed developmental origins from the yolk-sac and hematopoietic stem cells (HSC). They promote both injury and repair by regulating inflammation, angi
Externí odkaz:
https://doaj.org/article/4ed4b11be84440c6ad8f20ff6ae3ad22
Autor:
Yi‐Lin Zhang, Tao‐Tao Tang, Bin Wang, Yi Wen, Ye Feng, Qing Yin, Wei Jiang, Yue Zhang, Zuo‐Lin Li, Min Wu, Qiu‐Li Wu, Jing Song, Steven D. Crowley, Hui‐Yao Lan, Lin‐Li Lv, Bi‐Cheng Liu
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract The transition from acute kidney injury (AKI) to chronic kidney disease (CKD) is a critical clinical issue. Although previous studies have suggested macrophages as a key player in promoting inflammation and fibrosis during this transition, t
Externí odkaz:
https://doaj.org/article/04b2a5ecaaa14811809642c4813ba78f
Autor:
Yanting Chen, Xiaohan Lu, Raeann L. Whitney, Yu Li, Matthew J. Robson, Randy D. Blakely, Jen-Tsan Chi, Steven D. Crowley, Jamie R. Privratsky
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Introduction: Acute kidney injury (AKI) is one of the most common causes of organ failure in critically ill patients. Following AKI, the canonical pro-inflammatory cytokine interleukin-1β (IL-1β) is released predominantly from activated myeloid cel
Externí odkaz:
https://doaj.org/article/c578873524ba41d090b5725020c8e311
Autor:
C. Barrett Bowling, Maren K. Olsen, Theodore S. Z. Berkowitz, Battista Smith, Breana Floyd, Nadya Majette, Amy L. Miles, Steven D. Crowley, Virginia Wang, Matthew L. Maciejewski, Heather E. Whitson
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background The purpose of this manuscript is to introduce reserve and resilience as novel concepts in chronic kidney disease (CKD) research and present baseline data from a unique prospective cohort study designed to characterize recovery fr
Externí odkaz:
https://doaj.org/article/269b2dc614ac4d20a452734f99d44526
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 738 (2024)
Interleukins are a family of 40 bioactive peptides that act through cell surface receptors to induce a variety of intracellular responses. While interleukins are most commonly associated with destructive, pro-inflammatory signaling in cells, some als
Externí odkaz:
https://doaj.org/article/39fe32ff8732477987cea433f8163ae5
Autor:
Bo Yang, Steven D. Crowley
Publikováno v:
Physiological Reports, Vol 9, Iss 20, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/0a184493009e4035947447bb0cb2ff12
Autor:
Jiafa Ren, Yuemei Xu, Xiaohan Lu, Liming Wang, Shintaro Ide, Gentzon Hall, Tomokazu Souma, Jamie R. Privratsky, Robert F. Spurney, Steven D. Crowley
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
The transcription factor Twist1 regulates several processes that could impact kidney disease progression, including epithelial cell differentiation and inflammatory cytokine induction. Podocytes are specialized epithelia that exhibit features of immu
Externí odkaz:
https://doaj.org/article/8375eaae370841e0a7cb33cd4c61f063
Autor:
Hagir Suliman, Qing Ma, Zhiquan Zhang, Jiafa Ren, Benjamin T. Morris, Steven D. Crowley, Luis Ulloa, Jamie R. Privratsky
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Acute kidney injury (AKI) is one of the most common organ failures following surgery. We have developed a tripeptide mimetic (ANXA1sp) of the parent annexin A1 molecule that shows promise as an organ protectant limiting cellular stress; h
Externí odkaz:
https://doaj.org/article/d2d2b50a6d894524b9f4ffd58b90d1d2
Autor:
Hsin-I. Huang, Mark L. Jewell, Nourhan Youssef, Min-Nung Huang, Elizabeth R. Hauser, Brian E. Fee, Nathan P. Rudemiller, Jamie R. Privratsky, Junyi J. Zhang, Estefany Y. Reyes, Donghai Wang, Gregory A. Taylor, Michael D. Gunn, Dennis C. Ko, Donald N. Cook, Vidyalakshmi Chandramohan, Steven D. Crowley, Gianna Elena Hammer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets constituting the mononuclear phagocyte network are thought to be similar in both small and larg
Externí odkaz:
https://doaj.org/article/ec895c03dad444b39ecd52aa071d83d9