Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Steven D Bain"'
Autor:
Sundar Srinivasan, Danica Balsiger, Phillipe Huber, Brandon J Ausk, Steven D Bain, Edith M Gardiner, Ted S Gross
Publikováno v:
JBMR Plus, Vol 3, Iss 5, Pp n/a-n/a (2019)
Abstract Nearly all exogenous loading models of bone adaptation apply dynamic loading superimposed upon a time invariant static preload (SPL) in order to ensure stable, reproducible loading of bone. Given that SPL may alter aspects of bone mechanotra
Externí odkaz:
https://doaj.org/article/19809fc1f19446d38dac9cf82290ac51
Autor:
Leah E Worton, Edith M Gardiner, Ronald Y Kwon, Leah M Downey, Brandon J Ausk, Steven D Bain, Ted S Gross
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
At sufficient dose, intramuscular injection of Botulinum toxin A causes muscle wasting that is physiologically consistent with surgical denervation and other types of neuromuscular dysfunction. The aim of this study was to clarify early molecular and
Externí odkaz:
https://doaj.org/article/ee7fafa5d5b9490b868f4939f5190ce7
Autor:
Sundar Srinivasan, Dewayne Threet, Leah E Worton, Brandon J Ausk, Steven D Bain, Edith M Gardiner, Ronald Y Kwon, Ted S Gross
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84868 (2014)
Age-related decline in periosteal adaptation negatively impacts the ability to utilize exercise to enhance bone mass and strength in the elderly. We recently observed that in senescent animals subject to cyclically applied loading, supplementation wi
Externí odkaz:
https://doaj.org/article/d26bbf6752e7440a8222defa29f2697d
Autor:
Leah E Worton, Brandon J Ausk, Leah M Downey, Steven D Bain, Edith M Gardiner, Sundar Srinivasan, Ted S Gross, Ronald Y Kwon
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74205 (2013)
Bone has long been established to be a highly mechanosensitive tissue. When subjected to mechanical loading, bone exhibits profoundly different anabolic responses depending on the temporal pattern in which the stimulus is applied. This phenomenon has
Externí odkaz:
https://doaj.org/article/9c0c15401563429c86f952ae64e9efca
Autor:
Sundar Srinivasan, Brandon J Ausk, Jitendra Prasad, Dewayne Threet, Steven D Bain, Thomas S Richardson, Ted S Gross
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 9 (2010)
The increasing incidence of osteoporosis worldwide requires anabolic treatments that are safe, effective, and, critically, inexpensive given the prevailing overburdened health care systems. While vigorous skeletal loading is anabolic and holds promis
Externí odkaz:
https://doaj.org/article/c164276e84114afa9e358d8949de5b68
Autor:
Leah E. Worton, Sundar Srinivasan, DeWayne Threet, Brandon J. Ausk, Phillipe Huber, Ronald Y. Kwon, Steven D. Bain, Ted S. Gross, Edith M. Gardiner
Publikováno v:
JBMR Plus. 7
Autor:
Brandon J. Ausk, Ted S. Gross, Edith M. Gardiner, Leah E. Worton, Steven D. Bain, Ronald Y. Kwon, Leah M. Downey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207354 (2018)
At sufficient dose, intramuscular injection of Botulinum toxin A causes muscle wasting that is physiologically consistent with surgical denervation and other types of neuromuscular dysfunction. The aim of this study was to clarify early molecular and
Autor:
Sundar, Srinivasan, Danica, Balsiger, Phillipe, Huber, Brandon J, Ausk, Steven D, Bain, Edith M, Gardiner, Ted S, Gross
Publikováno v:
JBMR plus. 3(5)
Nearly all exogenous loading models of bone adaptation apply dynamic loading superimposed upon a time invariant static preload (SPL) in order to ensure stable, reproducible loading of bone. Given that SPL may alter aspects of bone mechanotransduction
Publikováno v:
Clinical Orthopaedics & Related Research. 473:2825-2830
Short-term muscle atrophy induced by botulinum toxin A (BTxA) has been observed to impair osteogenesis in a rat closed femur fracture model. However, it is unclear whether the underlying mechanism is a direct effect of BTxA on muscle-bone interaction
Autor:
Ted S. Gross, Ronald Y. Kwon, Edith M. Gardiner, Kate S. Smigiel, Steven D. Bain, Leah E. Worton, Sundar Srinivasan, Brandon J. Ausk
Transient muscle paralysis engendered by a single injection of botulinum toxin A (BTxA) rapidly induces profound focal bone resorption within the medullary cavity of adjacent bones. While initially conceived as a model of mechanical disuse, osteoclas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63840345e47978b7695c2933d342c3e8
https://europepmc.org/articles/PMC5792168/
https://europepmc.org/articles/PMC5792168/