Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Steven D, Rhodes"'
Autor:
Evan DuBose, Samantha M. Bevill, Dana K. Mitchell, Noah Sciaky, Brian T. Golitz, Shelley A. H. Dixon, Steven D. Rhodes, James E. Bear, Gary L. Johnson, Steven P. Angus
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionApproximately 50% of melanomas harbor an activating BRAFV600E mutation. Standard of care involves a combination of inhibitors targeting mutant BRAF and MEK1/2, the substrate for BRAF in the MAPK pathway. PTEN loss-of-function mutations oc
Externí odkaz:
https://doaj.org/article/858ea32fd4334cda9da5e4e67522fa6f
Autor:
Ka‐Kui Chan, Zahi Abdul‐Sater, Aditya Sheth, Dana K. Mitchell, Richa Sharma, Donna M. Edwards, Ying He, Grzegorz Nalepa, Steven D. Rhodes, D. Wade Clapp, Elizabeth A. Sierra Potchanant
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 860-884 (2022)
The Fanconi anemia (FA) pathway safeguards genomic stability through cell cycle regulation and DNA damage repair. The canonical tumor suppressive role of FA proteins in the repair of DNA damage during interphase is well established, but their functio
Externí odkaz:
https://doaj.org/article/af81c065551f42e1919675d6c2a442a5
Publikováno v:
Current Oncology Reports. 25:531-537
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c445423cddede459265ca418c1d21e3b
https://doi.org/10.1007/s11912-023-01388-3
https://doi.org/10.1007/s11912-023-01388-3
Publikováno v:
Case Reports in Critical Care, Vol 2020 (2020)
A two-year-old female presented with acutely altered mental status following eight days of fever and rash. She had been camping at an Indiana campground 11 days prior to the onset of illness and was evaluated twice for her fever and rash prior to adm
Externí odkaz:
https://doaj.org/article/ab320387607747808e775d11ef109546
Autor:
Peng Zhang, Caihong Xing, Steven D. Rhodes, Yongzheng He, Kai Deng, Zhaomin Li, Fuhong He, Caiying Zhu, Lihn Nguyen, Yuan Zhou, Shi Chen, Khalid S. Mohammad, Theresa A. Guise, Omar Abdel-Wahab, Mingjiang Xu, Qian-Fei Wang, Feng-Chun Yang
Publikováno v:
Stem Cell Reports, Vol 6, Iss 6, Pp 914-925 (2016)
Summary: De novo ASXL1 mutations are found in patients with Bohring-Opitz syndrome, a disease with severe developmental defects and early childhood mortality. The underlying pathologic mechanisms remain largely unknown. Using Asxl1-targeted murine mo
Externí odkaz:
https://doaj.org/article/a8fd63481cbe4c84b5d14195c86a0d88
Autor:
Richa Sharma, Zahi Abdul-Sater, Steven D. Rhodes, Grzegorz Nalepa, Elizabeth A. Sierra Potchanant, D. Wade Clapp, Dana Mitchell, Ying He, Aditya Sheth, Ka-Kui Chan, Donna Edwards
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 860-884 (2022)
The Fanconi anemia (FA) pathway safeguards genomic stability through cell cycle regulation and DNA damage repair. The canonical tumor suppressive role of FA proteins in the repair of DNA damage during interphase is well established, but their functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc309d1cfe540ce16b5fdb1d8659351d
https://doi.org/10.1002/1878-0261.13027
https://doi.org/10.1002/1878-0261.13027
Autor:
Yuan Zhou, Yongzheng He, Wen Xing, Peng Zhang, Hui Shi, Shi Chen, Jun Shi, Jie Bai, Steven D. Rhodes, Fengqui Zhang, Jin Yuan, Xianlin Yang, Xiaofan Zhu, Yan Li, Helmut Hanenberg, Mingjiang Xu, Kent A. Robertson, Weiping Yuan, Grzegorz Nalepa, Tao Cheng, D. Wade Clapp, Feng-Chun Yang
Publikováno v:
Haematologica, Vol 102, Iss 6 (2017)
Fanconi anemia is a complex heterogeneous genetic disorder with a high incidence of bone marrow failure, clonal evolution to acute myeloid leukemia and mesenchymal-derived congenital anomalies. Increasing evidence in Fanconi anemia and other genetic
Externí odkaz:
https://doaj.org/article/1121ed547efa4081b1fb6171d8e0fb48
Autor:
Yan Tong, Silpa Gampala, Ellie Rad, Ren Yuan Bai, Olivia Babb, Emily Hulsey, Fenil Shah, Chi Zhang, Steven D. Rhodes, Verena Staedtke, Randall Wireman, Brian L. Calver, Mark R. Kelley, Michelle Grimard, M. Reza Saadatzadeh, Abbi Smith, D. Wade Clapp, Andrew R. Tee, Karen E. Pollok, Melissa L. Fishel
Publikováno v:
British Journal of Cancer
Background MPNST is a rare soft-tissue sarcoma that can arise from patients with NF1. Existing chemotherapeutic and targeted agents have been unsuccessful in MPNST treatment, and recent findings implicate STAT3 and HIF1-α in driving MPNST. The DNA-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec69838060868f6ccae17ccdf078f1f2
http://europepmc.org/articles/PMC8076291
http://europepmc.org/articles/PMC8076291
Autor:
Steven P. Angus, Kwangmin Choi, Noah Sciaky, Katherine E. Chaney, Alexander Pemov, Florent Elefteriou, Andrea M. Gross, Jonathan J. Rios, Nancy Ratner, Steven D. Rhodes, Eva Dombi, Brigitte C. Widemann, D. Wade Clapp, Yun Ma
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics
Purpose Plexiform neurofibromas (NF) develop in children with Neurofibromatosis Type 1 (NF1) and can be associated with several skeletal co-morbidities. Preclinical mouse studies revealed Nf1 deficiency in osteoprogenitor cells disrupts, in a MEK-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1403bc987c36b76af61da93fddb7bacc
http://europepmc.org/articles/PMC8106869
http://europepmc.org/articles/PMC8106869
Autor:
Steven P. Angus, Steven D. Rhodes
Publikováno v:
Reference Module in Biomedical Sciences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0303496f7725d432eb8ae232285bfe8a
https://doi.org/10.1016/b978-0-12-820472-6.00174-2
https://doi.org/10.1016/b978-0-12-820472-6.00174-2
