Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Steven D, Levin"'
Autor:
Mark F. Maurer, Katherine E. Lewis, Joseph L. Kuijper, Dan Ardourel, Chelsea J. Gudgeon, Siddarth Chandrasekaran, Sherri L. Mudri, Kayla N. Kleist, Chris Navas, Martin F. Wolfson, Mark W. Rixon, Ryan Swanson, Stacey R. Dillon, Steven D. Levin, Yengo Raymond Kimbung, Masato Akutsu, Derek T. Logan, Björn Walse, Kristine M. Swiderek, Stanford L. Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
CD28 costimulatory signalling can be suppressed by immune checkpoints, such as CTLA-4 and PD-1. Here the authors describe the design of the fusion therapeutic davoceticept (ALPN-202), based on a variant CD80 extracellular domain engineered to bind PD
Externí odkaz:
https://doaj.org/article/1c1e0e459c4147429eef80ef95841f04
Autor:
Steven D. Levin, Lawrence S. Evans, Susan Bort, Erika Rickel, Katherine E. Lewis, Rebecca P. Wu, Joseph Hoover, Sean MacNeil, David La, Martin F. Wolfson, Mark W. Rixon, Stacey R. Dillon, Michael G. Kornacker, Ryan Swanson, Stanford L. Peng
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Immunoglobulin superfamily member (IgSF) proteins play a significant role in regulating immune responses with surface expression on all immune cell subsets, making the IgSF an attractive family of proteins for therapeutic targeting in human diseases.
Externí odkaz:
https://doaj.org/article/bed901c0bf43422ba8dc0a6914b60717
Autor:
Stacey R. Dillon, Lawrence S. Evans, Katherine E. Lewis, Susan Debrot, Tiffany C. Blair, Sherri Mudri, Kayla Kleist, Steven D. Levin, Janhavi G. Bhandari, Logan Garrett, Martin F. Wolfson, Pamela M. Holland, Mark W. Rixon, Stanford L. Peng
Publikováno v:
Arthritis & Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bed8247443c2f4840d627abb9e8554f
https://doi.org/10.1002/art.42484
https://doi.org/10.1002/art.42484
Autor:
Stanford L. Peng, Martin F. Wolfson, Ryan Swanson, Steven D. Levin, LS Evans, Kristine M. Swiderek, E Rickel, Katherine E. Lewis, Stacey R. Dillon
Publikováno v:
Cancer Research. 79:P1-20
This abstract was withdrawn by the authors. Citation Format: Dillon SR, Evans LS, Rickel E, Lewis KE, Swanson R, Levin SD, Wolfson M, Peng SL, Swiderek KM. Withdrawn [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff4a14b6df07797f3aa7616699327562
https://doi.org/10.1158/1538-7445.sabcs18-p1-20-03
https://doi.org/10.1158/1538-7445.sabcs18-p1-20-03
Autor:
Jing Yang, Steven D. Levin, Bruce R. Blazar, Kushi Kushekhar, Djamilatou Adom, Rebecca Wu, Katherine E. Lewis, Ryan Swanson, Hao Liu, Samantha Hund, Kristine M. Swiderek, Keli L. Hippen, Amanda Albright, Sophie Paczesny, Maykala Kirksey, Jinfeng Yang, Sherri Mudri, Stanford L. Peng, Erika Rickel, Katherine Henderson, Abdulraouf Ramadan, Lawrence Evans, Titilayo Adeniyan, Stacey R. Dillon, Michelle A. Seaberg, Martin F. Wolfson, Chelsea J. Gudgeon
Publikováno v:
Science Translational Medicine. 12
Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that mark activated T helper 17 (Th17) cells. The Th17 cell phenotype is promoted by the interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a57e0ff14e221647243917f957d6962
https://doi.org/10.1126/scitranslmed.aay4799
https://doi.org/10.1126/scitranslmed.aay4799
Autor:
Susan Bort, Katherine E. Lewis, Sean MacNeil, Stanford L. Peng, Mark W. Rixon, David La, Steven D. Levin, Erika Rickel, Ryan Swanson, Wu Rebecca, Lawrence Evans, Joseph Hoover, Martin F. Wolfson, Stacey R. Dillon, Michael Kornacker
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2020)
Frontiers in Immunology, Vol 10 (2020)
Immunoglobulin superfamily member (IgSF) proteins play a significant role in regulating immune responses with surface expression on all immune cell subsets, making the IgSF an attractive family of proteins for therapeutic targeting in human diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da80a6bda8596d993b32187a7cc99061
Autor:
Siddarth Chandrasekaran, Demonte Daniel William, Logan Garrett, Stanford L. Peng, Ardourel Daniel F, Katherine E. Lewis, Sherri Mudri, Mark F. Maurer, Kayla N. Kleist, Michelle A. Seaberg, Jing Yang, Steven D. Levin, Mark W. Rixon, Joseph L. Kuijper, Rachel Wang, Stacey R. Dillon, Hieu Nguyen, Chelsea J. Gudgeon, Martin F. Wolfson
Publikováno v:
Cancer Research. 81:1740-1740
Introduction: Checkpoint inhibition (CPI) has been shown to be an effective anti-tumor therapy, but CPI alone is frequently insufficient to control tumor growth, and costimulatory signals may also be required to produce clinically significant anti-tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad26d42c81f0996e63429f20a500526e
https://doi.org/10.1158/1538-7445.am2021-1740
https://doi.org/10.1158/1538-7445.am2021-1740
Autor:
Djamilatou, Adom, Stacey R, Dillon, Jinfeng, Yang, Hao, Liu, Abdulraouf, Ramadan, Kushi, Kushekhar, Samantha, Hund, Amanda, Albright, Maykala, Kirksey, Titilayo, Adeniyan, Katherine E, Lewis, Lawrence, Evans, Rebecca, Wu, Steven D, Levin, Sherri, Mudri, Jing, Yang, Erika, Rickel, Michelle, Seaberg, Katherine, Henderson, Chelsea J, Gudgeon, Martin F, Wolfson, Ryan M, Swanson, Kristine M, Swiderek, Stanford L, Peng, Keli L, Hippen, Bruce R, Blazar, Sophie, Paczesny
Publikováno v:
Sci Transl Med
Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that mark activated T helper 17 (Th17) cells. The Th17 cell phenotype is promoted by the interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::702e374a5e60a489b389152613e0b915
https://pubmed.ncbi.nlm.nih.gov/33028709
https://pubmed.ncbi.nlm.nih.gov/33028709
Autor:
S. Mudri, J. Hillson, C. Gudgeon, L. S. Evans, R. Wang, M. A. Seaberg, D. Demonte, R. Sanderson, D. Ardourel, M. W. Rixon, Steven D. Levin, K. Kleist, S. L. Peng, M. F. Wolfson, J. Kuijper, Katherine E. Lewis, Stacey R. Dillon, J. Yang, J. Bhandari, S. Bort
Publikováno v:
Annals of the Rheumatic Diseases. 80:21.2-21
Background:BAFF and APRIL are TNF superfamily members that form homo- and heteromultimers that bind TACI and BCMA on B cells; BAFF also binds BAFF-R. BAFF and APRIL support B cell development, differentiation, and survival, particularly for plasmabla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4e2273ed2109e7f533a42698edcd4d
https://doi.org/10.1136/annrheumdis-2021-eular.727
https://doi.org/10.1136/annrheumdis-2021-eular.727
Autor:
Kristine M. Swiderek, Siddarth Chandrasekaran, Stanford L. Peng, Katherine E. Lewis, Steven D. Levin, Fariha Ahmed-Qadri, Sherri Mudri, Chelsea J. Gudgeon, Kayla N. Kleist, Stacey R. Dillon, Mark F. Maurer
Publikováno v:
Cancer Research. 80:LB-085
Background: Despite significant clinical benefit of checkpoint inhibitors (CPI) in some settings, unfortunately, the majority of patients still fail to respond and/or develop resistance. This is likely due to a complex set of factors including, but n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac9eadb257650bb7d4c069a5fd55fe08
https://doi.org/10.1158/1538-7445.am2020-lb-085
https://doi.org/10.1158/1538-7445.am2020-lb-085