Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Steven Collins"'
Autor:
Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G Kovacs, Michael D Geschwind, Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J van der Lee, Cornelia M van Duijn, Pawel P Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Stéphane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr, Brian S Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304528 (2024)
Human prion diseases are rare, transmissible and often rapidly progressive dementias. The most common type, sporadic Creutzfeldt-Jakob disease (sCJD), is highly variable in clinical duration and age at onset. Genetic determinants of late onset or slo
Externí odkaz:
https://doaj.org/article/a8105e366d44473aa02be9676f81d759
Autor:
Placide Mahougnan Toklo, Géorcelin G. Alowanou, Steven Collins N. Wouamba, Fidèle M. Assogba, Mathias A. Ahomadegbe, Amoussatou Sakirigui, Bruno Ndjakou Lenta, Sylvie Hounzangbe-Adote, Simeon Fogue Kouam, Eléonore C. Yayi-Ladekan, Joachim Djimon Gbenou
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16448- (2023)
Medicinal plants attract the attention of many researchers to find natural and safe remedies for various resistant diseases. Leaves of Mitragyna inermis are widely used in traditional veterinary medicine for the treatment of gastrointestinal strongyl
Externí odkaz:
https://doaj.org/article/f03f2a12349a4d2f9cb4a448c31d7a95
Bio-guided isolation of anti-leishmanial natural products from Diospyros gracilescens L. (Ebenaceae)
Autor:
Cyrille Armel N. Njanpa, Steven Collins N. Wouamba, Lauve Rachel T. Yamthe, Darline Dize, Brice Mariscal T. Tchatat, Patrick Valère F. Tsouh, Michel Nguiam Pouofo, Jean Bosco Jouda, Bruno Lenta Ndjakou, Norbert Sewald, Simeon Fogue Kouam, Fabrice Fekam Boyom
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Plants represent an intricate and innovative source for the discovery of novel therapeutic remedies for the management of infectious diseases. The current study aimed at discovering new inhibitors of Leishmania spp., using anti-le
Externí odkaz:
https://doaj.org/article/ac1af3e37b1e46c3b283215bd434329e
Autor:
James D. Doecke, Larry Ward, Samantha C. Burnham, Victor L. Villemagne, Qiao-Xin Li, Steven Collins, Christopher J. Fowler, Ekaterina Manuilova, Monika Widmann, Stephanie R. Rainey-Smith, Ralph N. Martins, Colin L. Masters, the AIBL Research Group
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background β-amyloid (Aβ) positron emission tomography (PET) imaging is currently the only Food and Drug Administration-approved method to support clinical diagnosis of Alzheimer’s disease (AD). However, numerous research studies support
Externí odkaz:
https://doaj.org/article/ca236dd529884d0a927880e177f12915
Autor:
Lucy Vivash, Dennis Velakoulis, Terence J O’Brien, Charles B Malpas, Amy Brodtmann, Christopher M Hovens, Steven Collins, Stephen Macfarlane
Publikováno v:
BMJ Neurology Open, Vol 3, Iss 2 (2021)
Introduction Sodium selenate is a potential disease-modifying treatment for Alzheimer’s disease (AD) which reduces hyperphosphorylated tau through activation of the protein phosphatase 2A enzyme. We have shown sodium selenate to be safe and well to
Externí odkaz:
https://doaj.org/article/c635a5b7fee8411fa1aea2b913960bf3
Autor:
Utpal Kumar Adhikari, Elif Sakiz, Umma Habiba, Meena Mikhael, Matteo Senesi, Monique Antoinette David, Gilles J. Guillemin, Lezanne Ooi, Tim Karl, Steven Collins, Mourad Tayebi
Publikováno v:
Heliyon, Vol 7, Iss 12, Pp e08644- (2021)
Previous reports highlighted the neurotoxic effects caused by some motif-specific anti-PrPC antibodies in vivo and in vitro. In the current study, we investigated the detailed alterations of the proteome with liquid chromatography–mass spectrometry
Externí odkaz:
https://doaj.org/article/8c747a79e2b747f7a7f2d9d7285a4697
Autor:
Craig Anderson, Steven Collins, Miriam Welgampola, Rajiv Wijesinghe, Christine Stehmann, Penelope Spring
Publikováno v:
BMJ Neurology Open, Vol 3, Iss Suppl 1 (2021)
Externí odkaz:
https://doaj.org/article/05009a16baa64d6e98cebec262b6c2a6
Autor:
Utpal Kumar Adhikari, Elif Sakiz, Xian Zhou, Umma Habiba, Sachin Kumar, Meena Mikhael, Matteo Senesi, Chun Guang Li, Gilles J. Guillemin, Lezanne Ooi, Monique Antoinette David, Steven Collins, Tim Karl, Mourad Tayebi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundPrevious reports identified proteins associated with ‘apoptosis’ following cross-linking PrPC with motif-specific anti-PrP antibodies in vivo and in vitro. The molecular mechanisms underlying this IgG-mediated neurotoxicity and the role
Externí odkaz:
https://doaj.org/article/b0106608964342d4984075a257e4e7ea
Autor:
Kunal Dhiman, Victor L. Villemagne, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Ashley I. Bush, Christopher C. Rowe, Colin L. Masters, David Ames, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins, Veer Gupta
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1045 (2022)
Background: Biomarkers that are indicative of early biochemical aberrations are needed to predict the risk of dementia onset and progression in Alzheimer’s disease (AD). We assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL)
Externí odkaz:
https://doaj.org/article/f02d7207870d46cd8d5801b8507b29f1
Autor:
Kunal Dhiman, Veer Bala Gupta, Victor L. Villemagne, Dhamidhu Eratne, Petra L. Graham, Christopher Fowler, Pierrick Bourgeat, Qiao‐Xin Li, Steven Collins, Ashley I. Bush, Christopher C. Rowe, Colin L. Masters, David Ames, Eugene Hone, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) diagnosis, its association with amyloid and tau pathology, as well as its potential to predict brain atrophy, cog
Externí odkaz:
https://doaj.org/article/365c6fec1fde4184b2c9e8e883ae53b3