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pro vyhledávání: '"Steven Chaney"'
Autor:
Mark J. Benvenga, Michael A. Statnick, Karen M. Knitowski, Julie Foss, Miguel A. Toledo, Alfonso Benito, Anke Post, Kirsti Lloyd, Michael Ansonoff, Alma Jiménez, Vanessa N. Barth, Maria Angeles Martinez-Grau, Janice W. Smith, Scott D. Gleason, Celia Lafuente, Linda M. Rorick-Kehn, John T. Catlow, Conception Pedregal, Nuria Diaz, Julie F. Falcone, Kjell A. Svensson, John E. Pintar, Steven Chaney, Xia Li, David L. McKinzie, Benjamin L. Adams, Jeffrey M. Witkin
Publikováno v:
Pharmacology Research & Perspectives
Nociceptin/Orphanin FQ (N/OFQ) is a 17 amino acid peptide whose receptor is designated ORL1 or nociceptin receptor (NOP). We utilized a potent, selective, and orally bioavailable antagonist with documented engagement with NOP receptors in vivo to ass