Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Steven Challand"'
Autor:
Apollon Papadimitriou, Lutz Müller, Julia Heinrich, Martin Schäfer, Steven Challand, Katja Heinig, Dominik Hainzl, Sabine Bader, Eginhard Schick
Publikováno v:
Bioanalysis. 7(24)
Background: During development of biologics, safety and efficacy assessments are often hampered by immune responses to the treatment. To assess active exposure of a drug peptide in a toxicology study, we developed an ex vivo potency assay which compl
Autor:
Gabrielle Heilek-Snyder, Jun Zhang, Changhua Ji, Gunthar Achhammer, Nick Cammack, Steven Challand, Ralf Schumacher, Monika Baehner, Surya Sankuratri, Andreas Jekle, Sandra Kroetz, Michael Brandt, Lisa Zautke, Stephan Schwoerer, Marianna Dioszegi, Yun Chen
Publikováno v:
Antiviral Research. 74:125-137
To identify monoclonal antibodies (mAbs) with high potency and novel recognition sites, more than 25,000 of mouse hybridomas were screened and 4 novel anti-human CCR5 mAbs ROAb12, ROAb13, ROAb14, and ROAb18 showing potent activity in cell-cell fusion