Výsledky vyhledávání - "Steven C. Verberckmoes"

Autor: Dieter Haffner, Steven C. Verberckmoes, Ellen Neven, A. Hufkens, Geert J. Behets, Dominik N. Müller, Uwe Querfeld, Hong Zebger-Gong, Veerle P. Persy, M. E. De Broe, Sylvain Bohic, Patrick C. D'Haese

Publikováno v: Kidney international

In the present study, we characterized and compared the mineral phase deposited in the aortic wall of two different frequently used chronic renal failure rat models of vascular calcification. Vascular calcification was induced in rats by either a 4-w

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Strontium incorporates at sites critical for bone mineralization in rats with renal failure

Autor: Sylvain Bohic, Geert Dams, Patrick C. D'Haese, Steven C. Verberckmoes, Marc E. De Broe, An R. Bervoets, Michael Drakopoulos, Viviane Van Hoof, Geert J. Behets, Line Oste

Publikováno v: X-ray spectrometry

We previously demonstrated the development of a mineralization defect during strontium administration and its reversibility after withdrawal in rats with chronic renal failure. Recently, strontium ranelate has been introduced as a therapeutic agent f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c710d303e8aa1fb595e0f1e7767b3f10
https://doi.org/10.1002/xrs.929

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Localization of lanthanum in bone of chronic renal failure rats after oral dosing with lanthanum carbonate

Autor: Steven C. Verberckmoes, John Denton, Murielle Salomé, Alan G. Cox, Patrick C. D'Haese, An R. Bervoets, Marc E. De Broe, Geert J. Behets, Line Oste

Publikováno v: Kidney International. 67:1830-1836

Localization of lanthanum in bone of chronic renal failure rats after oral dosing with lanthanum carbonate. Background Lanthanum carbonate has been shown to be a safe, effective phosphate-binding agent. We have shown that an impaired mineralization i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839f372aa9a93fcb2b6ff61781ffaf21
https://doi.org/10.1111/j.1523-1755.2005.00281.x

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Dose-dependent effects of strontium on osteoblast function and mineralization

Autor: Marc E. De Broe, Patrick C. D'Haese, Steven C. Verberckmoes

Publikováno v: Kidney international

Dose-dependent effects of strontium on osteoblast function and mineralization. Background Strontium-ranelate is now being used in the treatment of osteoporosis in elderly patients. As the majority of these patients already have a decreased renal func

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1,25-Dihydroxyvitamin D3-induced aortic calcifications in experimental uremia: up-regulation of osteoblast markers, calcium-transporting proteins and osterix

Autor: Steven C. Verberckmoes, Sven Schmidt, Patrick C. D'Haese, Dominik N. Müller, Hong Zebger-Gong, Berthold Hocher, Dieter Haffner, Michaela Diercke, Uwe Querfeld

Publikováno v: Journal of hypertension

Background and objective: Whether treatment with vitamin D receptor activators contributes to cardiovascular disease in patients with chronic kidney disease is a matter of debate. We studied mechanisms involved in vitamin D-related vascular calcifica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a1ec052c0025aca65f920e9bcd053e
https://pubmed.ncbi.nlm.nih.gov/21063202

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Ultrastructural analysis of vascular calcifications in uremia

Autor: Anke Aretz, Jürgen Floege, Vincent Brandenburg, Stephan Langer, Jan H.M. Tordoir, Steven C. Verberckmoes, Joachim Mayer, Thomas E. Weirich, Reza Ghadimi, Kerstin Amann, Markus Ketteler, Ralf Westenfeld, Patrick C. D'Haese, Dorothea Rohrmann, Georg Schlieper, Geert J. Behets, Thilo Krüger, Marc D. McKee

Publikováno v: Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, 21(4), 689-696. American Society of Nephrology

Accelerated intimal and medial calcification and sclerosis accompany the increased cardiovascular mortality of dialysis patients, but the pathomechanisms initiating microcalcifications of the media are largely unknown. In this study, we systematicall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fa32aa2e6c407c188a8ea0f8b977f1
https://pubmed.ncbi.nlm.nih.gov/20203159

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Hepatocellular transport and gastrointestinal absorption of lanthanum in chronic renal failure

Autor: Steven C. Verberckmoes, Simonne Dauwe, Ronny Blust, D. Schryvers, Marc E. De Broe, Geert J. Behets, Valentine K. Mubiana, An R.J. Bervoets, Stephen J.P. Damment, Frank Roels, Zhang Yang, Patrick C. D'Haese

Publikováno v: Kidney international

Lanthanum carbonate is a new phosphate binder that is poorly absorbed from the gastrointestinal tract and eliminated largely by the liver. After oral treatment, we and others had noticed 23 fold higher lanthanum levels in the livers of rats with chro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec572832bcf2c7b0d7a66bb16a72493
https://hdl.handle.net/10067/722900151162165141

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Time-evolution and reversibility of strontium-induced osteomalacia in chronic renal failure rats

Autor: An R. Bervoets, Marc E. De Broe, Geert Dams, Viviane Van Hoof, Rita L. Marijnissen, Geert J. Behets, Patrick C. D'Haese, Ludwig V. Lamberts, Steven C. Verberckmoes, Line Oste, Hilde Geryl

Publikováno v: Kidney international

Time-evolution and reversibility of strontium-induced osteomalacia in chronic renal failure rats. Background Patients with impaired renal function can accumulate strontium in the bone, which has been associated with the development of osteomalacia. A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c05b38d153f7d22f17e4fd8663cbad
https://pubmed.ncbi.nlm.nih.gov/15698431

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Lanthanum carbonate: a new phosphate binder

Autor: Patrick C. D'Haese, Marc E. De Broe, Steven C. Verberckmoes, Geert J. Behets

Publikováno v: Current opinion in nephrology and hypertension

Hyperphosphatemia remains an important aspect in the management of end-stage renal disease patients. Consequently, there is a need for new, efficient and well-tolerated phosphate binders. In this review, a new phosphate-binding drug, lanthanum carbon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a108d5502d6037e7fec1a7550acfcdc
https://pubmed.ncbi.nlm.nih.gov/15199290

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