Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Steven C. Neier"'
Autor:
Emily A. Brown, Jonathan D. Lautz, Tessa R. Davis, Edward P. Gniffke, Alison A. W. VanSchoiack, Steven C. Neier, Noah Tashbook, Chiara Nicolini, Margaret Fahnestock, Adam G. Schrum, Stephen E. P. Smith
Publikováno v:
Molecular Autism, Vol 9, Iss 1, Pp 1-16 (2018)
Abstract Background Autism spectrum disorders (ASDs) are a heterogeneous group of behaviorally defined disorders and are associated with hundreds of rare genetic mutations and several environmental risk factors. Mouse models of specific risk factors
Externí odkaz:
https://doaj.org/article/a2fc5de9ecba4cf09af343f1cfbed31d
Autor:
Karyn Schmidt, Johanna S. Carroll, Elaine Yee, Dolly D. Thomas, Leon Wert-Lamas, Steven C. Neier, Gloria Sheynkman, Justin Ritz, Carl D. Novina
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2493-2507.e4 (2019)
Summary: Melanoma is the deadliest form of skin cancer, affecting men more frequently and severely than women. Although recent studies suggest that differences in activity of the androgen receptor (AR) underlie the observed sex bias, little is known
Externí odkaz:
https://doaj.org/article/596f218635ae4074aba56476daea8a07
Autor:
Aya Kobayashi, Alberto Nobili, Steven C. Neier, Amissi Sadiki, Robert Distel, Zhaohui Sunny Zhou, Carl D. Novina
Publikováno v:
ChemMedChem. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbaed57e7df87f2f4dce8fa25df55055
https://doi.org/10.1002/cmdc.202200309
https://doi.org/10.1002/cmdc.202200309
Autor:
Aya Kobayashi, Alberto Nobili, Steven C. Neier, Amissi Sadiki, Robert Distel, Zhaohui Sunny Zhou, Carl D. Novina
Publikováno v:
ChemMedChem. 17(12)
Major challenges to chimeric antigen receptor (CAR) T cell therapies include uncontrolled immune activity, off-tumor toxicities and tumor heterogeneity. To overcome these challenges, we engineered CARs directed against small molecules. By conjugating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ff37dbe1faa8579c1e7412ddd0650f
https://pubmed.ncbi.nlm.nih.gov/35146940
https://pubmed.ncbi.nlm.nih.gov/35146940
Autor:
Jonathan D. Lautz, Tessa R. Davis, Steven C. Neier, Stephen E. P. Smith, Chiara Nicolini, Noah Tashbook, Emily A. Brown, Alison A. Williams VanSchoiack, Edward P. Gniffke, Margaret Fahnestock, Adam G. Schrum
Publikováno v:
Molecular Autism, Vol 9, Iss 1, Pp 1-16 (2018)
Background Autism spectrum disorders (ASDs) are a heterogeneous group of behaviorally defined disorders and are associated with hundreds of rare genetic mutations and several environmental risk factors. Mouse models of specific risk factors have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7447adbaee1d9e71e9dd1c124f8c319
http://link.springer.com/article/10.1186/s13229-018-0229-1
http://link.springer.com/article/10.1186/s13229-018-0229-1
Autor:
Barry K. Gilbert, Robert W. Techentin, Adam D. Scheid, Steven C. Neier, Larry R. Pease, Yuji Zhang, Sara J. Felts, Virginia P. Van Keulen, Claudia Neuhauser, Asha Nair, Sumit Middha, Jin Jen
Publikováno v:
The Journal of Immunology. 200:1917-1928
Human immunity exhibits remarkable heterogeneity among individuals, which engenders variable responses to immune perturbations in human populations. Population studies reveal that, in addition to interindividual heterogeneity, systemic immune signatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2227505a70282e1f3cce456e6b9387ec
https://doi.org/10.4049/jimmunol.1701099
https://doi.org/10.4049/jimmunol.1701099
Publikováno v:
Journal of visualized experiments : JoVE. (150)
Dynamic protein-protein interactions control cellular behavior, from motility to DNA replication to signal transduction. However, monitoring dynamic interactions among multiple proteins in a protein interaction network is technically difficult. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08242a67b030474e552f322ce1676253
https://pubmed.ncbi.nlm.nih.gov/31498315
https://pubmed.ncbi.nlm.nih.gov/31498315
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fae21583d8366909d4644b4d7c28893
https://doi.org/10.3791/60029-v
https://doi.org/10.3791/60029-v
Autor:
Tessa R. Davis, Aaron J. Johnson, Jamie Rossjohn, Mark A. Daniels, Alejandro Ferrer, Adam G. Schrum, Deanne Hebrink, Kevin D. Pavelko, Stephen E. P. Smith, Jenna M. Canfield, Katelynn M. Wilton, Peter J. Wettstein, Dietmar J. Kappes, Diana Gil, Larry R. Pease, Scott R. Burrows, James McCluskey, April M. Huseby Kelcher, Claudia Neuhauser, Zhenjun Chen, Steven C. Neier, Eva M. Carmona, Andrew H. Limper, Robert J. Stiles
Publikováno v:
Sci Immunol
During αβ T cell development, T cell antigen receptor (TCR) engagement transduces biochemical signals through a protein-protein interaction (PPI) network that dictates dichotomous cell fate decisions. It remains unclear how signal specificity is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fad1a3e06f1347ccfdcf6b2fb62e3d
https://doi.org/10.1126/sciimmunol.aal2201
https://doi.org/10.1126/sciimmunol.aal2201
Autor:
Jenna M Canfield, Alejandro Ferrer, Steven C Neier, Katelynn M Wilton, Robert J Stiles, Tessa Davis, Adam G Schrum, Diana Gil Pages
Publikováno v:
The Journal of Immunology. 204:61.15-61.15
Upon positive selection of conventional αβ T cells, CD4+ CD8+ double-positive (DP) cells transition to single-positive (SP) and reduce their responsiveness to weak peptide/MHC ligands (affinity threshold conversion, ATC). We report that ATC actuall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b95605fccbad6c768fd129089240a81
https://doi.org/10.4049/jimmunol.204.supp.61.15
https://doi.org/10.4049/jimmunol.204.supp.61.15