Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Steven C. Mitini-Nkhoma"'
Autor:
Steven C. Mitini-Nkhoma, Elizabeth T. Chimbayo, David T. Mzinza, David V. Mhango, Aaron P. Chirambo, Christine Mandalasi, Agness E. Lakudzala, Dumizulu L. Tembo, Kondwani C. Jambo, Henry C. Mwandumba
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tuberculosis (TB) remains a challenging global health concern and claims more than a million lives every year. We lack an effective vaccine and understanding of what constitutes protective immunity against TB to inform rational vaccine design. Moreov
Externí odkaz:
https://doaj.org/article/d3bcd51be303437eab5077b3754b718d
Ion Transport Modulators Differentially Modulate Inflammatory Responses in THP-1-Derived Macrophages
Autor:
Steven C. Mitini-Nkhoma, Narmada Fernando, G. K. D. Ishaka, Shiroma M. Handunnetti, Sisira L. Pathirana
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Ion transport modulators are most commonly used to treat various noncommunicable diseases including diabetes and hypertension. They are also known to bind to receptors on various immune cells, but the immunomodulatory properties of most ion transport
Externí odkaz:
https://doaj.org/article/9d9d715dbe434b72b282d4da2bdddb72
Autor:
Steven C. Mitini-Nkhoma, Narmada Fernando, G. K. D. Ishaka, Shiroma M. Handunnetti, Sisira L. Pathirana
Publikováno v:
Tuberculosis Research and Treatment, Vol 2020 (2020)
There is an urgent need for better and safer therapeutic interventions for tuberculosis (TB). We assessed the effects of FDA-approved ion transport modulators, namely, ambroxol HCl, amiloride HCl, diazoxide, digoxin, furosemide, hydrochlorothiazide (
Externí odkaz:
https://doaj.org/article/d68941a5a616416b9172601876e163fb
Autor:
Steven C. Mitini-Nkhoma, David T. Mzinza, Elizabeth T. Chimbayo, Aaron P. Chirambo, David V. Mhango, Cheusisime Kajanga, Christine Mandalasi, Dumizulu L. Tembo, Jane Mallewa, Leo Masamba, David G. Russell, Kondwani C. Jambo, S. Bertie Squire, Henry C. Mwandumba
Publikováno v:
AIDS (London, England). 36(15)
Autor:
Narmada Fernando, Sisira Pathirana, G K D Ishaka, Steven C Mitini-Nkhoma, Shiroma M. Handunnetti
Publikováno v:
Tuberculosis Research and Treatment
Tuberculosis Research and Treatment, Vol 2020 (2020)
Tuberculosis Research and Treatment, Vol 2020 (2020)
There is an urgent need for better and safer therapeutic interventions for tuberculosis (TB). We assessed the effects of FDA-approved ion transport modulators, namely, ambroxol HCl, amiloride HCl, diazoxide, digoxin, furosemide, hydrochlorothiazide (
Autor:
Kondwani C. Jambo, Davide Pisu, David Mzinza, Gabrielle Lê-Bury, Monique E. Theriault, David V Mhango, Amit Singhal, Lu Huang, Steven C. Mitini-Nkhoma, Agnes E Lakudzala, Bernett Lee, Vipin Narang, David G. Russell, Henry C. Mwandumba
Publikováno v:
The Journal of Experimental Medicine
Through scRNA-seq and ATAC-seq, Pisu et al. characterize specific lung macrophage subsets that either restrict or promote M. tuberculosis growth. Comparable macrophage populations are present in the human airways, and cells show evidence of epigeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609b1f0634bad27450712873b9527f39
https://archive.lstmed.ac.uk/18616/1/Mwandumba_Jambo_JEM2021.pdf
https://archive.lstmed.ac.uk/18616/1/Mwandumba_Jambo_JEM2021.pdf
Autor:
Christine Mandalasi, Elizabeth Chimbayo, Agness Lakudzala, David Mzinza, Henry C. Mwandumba, David V Mhango, Kondwani C. Jambo, Steven C. Mitini-Nkhoma, Aaron P. Chirambo, Dumizulu L. Tembo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Tuberculosis (TB) remains a challenging global health concern and claims more than a million lives every year. We lack an effective vaccine and understanding of what constitutes protective immunity against TB to inform rational vaccine design. Moreov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb052b073773d326f77c70246ba1ee5c
Ion transport modulators differentially modulate inflammatory responses in THP-1 derived macrophages
Autor:
Narmada Fernando, Steven C Mitini-Nkhoma, G K D Ishaka, Sisira Pathirana, Shiroma M. Handunnetti
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
Ion transport modulators are most commonly used to treat various non-communicable diseases including diabetes and hypertension. They are also known to bind to receptors on various immune cells, but the immunomodulatory properties of most ion transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fcdf3e5e978bdf6f9ce441217c71a3
https://doi.org/10.1101/2021.03.21.436302
https://doi.org/10.1101/2021.03.21.436302
Using Mobile Phones For Computer Aided Detection Of Anomalies On Chest Radiographs: Proof Of Concept
Autor:
Steven C. Mitini-Nkhoma
Mastering the art of interpreting chest radiographs can be a long and daunting process. We trained a neural network to classify photographs of chest radiographs into 6 groups. The trained model is hosted on a webserver. The model receives and process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef4d8346fd58aae3a21ca5cdd636d2f