Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Steven C. Cassar"'
Autor:
Uwe Müller, Teresa Ellis, Wayne R. Buck, Bradley A. Hooker, Ann Tovcimak, Nathan R. Rustay, Steven C. Cassar, Dancia Scharf, Jeffrey F. Waring, Kevin K.W. Wang, Jinhe Li, Andreas Jeromin, David G. Witte
Publikováno v:
Journal of Neuroscience Methods. 192:249-253
Cerebrospinal fluid (CSF) is commonly used for assessing biomarkers of drug efficacy or disease progression in the central nervous system. Studies of CSF from pre-clinical species can characterize biomarkers for use in clinical trials. However, obtai
Autor:
Russell A. Judge, Anil Vasudevan, Victoria E. Scott, Gricelda H. Simler, Steve D. Pratt, Marian T. Namovic, C. Brent Putman, Ana Aguirre, Vincent S. Stoll, Mulugeta Mamo, Steven I. Swann, Steven C. Cassar, Connie R. Faltynek, Karen L. Kage, Janel M. Boyce-Rustay, Adrian D. Hobson
Publikováno v:
ChemBioChem. 19:890-890
Autor:
Gerard B. Fox, John D. Beaver, Ann Tovcimak, Jaymin Upadhyay, Michelle Hart, Prisca Honore, Bradley A. Hooker, Rajesh V. Kamath, Rajasimhan Rajagovindan, Scott J. Baker, Joseph P. Mikusa, Prasant Chandran, Anthony Bannon, Michael J. Wald, Shailen K. Joshi, Mark Day, Steven C. Cassar, Jeroen K. Medema
Publikováno v:
NeuroImage. 64
The earliest stages of osteoarthritis are characterized by peripheral pathology; however, during disease progression chronic pain emerges-a major symptom of osteoarthritis linked to neuroplasticity. Recent clinical imaging studies involving chronic p
Publikováno v:
Molecular vision. 10
The cyclic nucleotide gated cation channel subunit, CNGA3, (also known as the cone alpha CNG subunit), plays a vital role in signal transduction of human cone cells. Owing to its well established role in vision, the human CNGA3 isoform studied thus f
Autor:
Stanley Bukofzer, Linda E. Gustavson, Jill E. Polzin, Maria C. Gentile, Xin Ye, Robert F. O'Dea, David A. Katz, Steven C. Cassar, Laura A. Williams, Matthew J. Rieser, Eric F. Gordon, Dirk Grimm, Rita M. Driscoll
Publikováno v:
Clinical pharmacology and therapeutics. 75(6)
Background The metabolizing enzyme cytochrome P450 (CYP) 3A5 is polymorphically expressed as a result of genetic variants that do not encode functional protein. Because of overlapping substrate specificity with CYP3A4 and the multidrug efflux pump P-