Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Steven C. Bakker"'
Autor:
Steven C. Bakker, Iris E. C. Sommer, Jasper O. Nuninga, Wendy Nieuwdorp, Sophie M. Heringa, René S. Kahn, René C.W. Mandl, Peter R. Luijten, Marco P. Boks, Metten Somers, Hans Hoogduin
Publikováno v:
Molecular Psychiatry, 25(7), 1559-1568. Nature Publishing Group
Electroconvulsive therapy (ECT) is the most effective treatment for depression, yet its working mechanism remains unclear. In the animal analog of ECT, neurogenesis in the dentate gyrus (DG) of the hippocampus is observed. In humans, volume increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bd54c102f40dcba81cffdc22d0b1db
https://research.rug.nl/en/publications/93225e8d-d28f-4472-8234-aeadcc9a917b
https://research.rug.nl/en/publications/93225e8d-d28f-4472-8234-aeadcc9a917b
Autor:
Jurjen J Luykx, Steven C Bakker, Eef Lentjes, Marco P M Boks, Nan van Geloven, Marinus J C Eijkemans, Esther Janson, Eric Strengman, Anne M de Lepper, Herman Westenberg, Kai E Klopper, Hendrik J Hoorn, Harry P M M Gelissen, Julian Jordan, Noortje M Tolenaar, Eric P A van Dongen, Bregt Michel, Lucija Abramovic, Steve Horvath, Teus Kappen, Peter Bruins, Peter Keijzers, Paul Borgdorff, Roel A Ophoff, René S Kahn
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30497 (2012)
BACKGROUND: Animal studies have revealed seasonal patterns in cerebrospinal fluid (CSF) monoamine (MA) turnover. In humans, no study had systematically assessed seasonal patterns in CSF MA turnover in a large set of healthy adults. METHODOLOGY/PRINCI
Externí odkaz:
https://doaj.org/article/f131df95cc434aeb9294f7983f15bdae
Autor:
Jasper O. Nuninga, Steven C. Bakker, Metten Somers, Marco P. Boks, Marieke J.H. Begemann, Sophie M. Heringa, Wendy Nieuwdorp, René C.W. Mandl, Thomas F.I. Claessens, Iris E. C. Sommer
Publikováno v:
Journal of Affective Disorders, 238, 659-665. ELSEVIER SCIENCE BV
Journal of Affective Disorders, 238, 659. Elsevier
Journal of Affective Disorders, 238, 659. Elsevier
Background: Electroconvulsive therapy (ECT) is the most effective treatment for patients suffering from major depression. However, its use is limited due to concerns about negative effects on cognition. Unilateral ECT is associated with transient cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c621f80ce8580f1b8907248b5252215
https://research.rug.nl/en/publications/7671d49c-6ad6-42aa-a38e-a30604eadca7
https://research.rug.nl/en/publications/7671d49c-6ad6-42aa-a38e-a30604eadca7
Autor:
Roel A. Ophoff, Steven C. Bakker, Jurjen J. Luykx, Jacobine E. Buizer-Voskamp, Wouter W. van Solinge, Hanneke den Breeijen, Maarten J. ten Berg, Simone de Jong, Steve Horvath, Eric Strengman, Marjolein Neeleman, René S. Kahn, Leon C. Stijvers
Publikováno v:
Human Molecular Genetics. 23:2721-2728
Seasonal patterns in behavior and biological parameters are widespread. Here, we examined seasonal changes in whole blood gene expression profiles of 233 healthy subjects. Using weighted gene co-expression network analysis, we identified three co-exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8abbae1e8235ed761f7ea34d26d15ed
https://doi.org/10.1093/hmg/ddt665
https://doi.org/10.1093/hmg/ddt665
Publikováno v:
Neuroscience & Biobehavioral Reviews. 37:1587-1596
Serine and other amino acids that function as coagonists at the N-methyl- d -aspartate receptor (NMDAR) have been extensively investigated in schizophrenia (SCZ). However, studies comparing amino acid levels in body fluids of SCZ patients with health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4de487825b7bb31ed899c94d6ef5a6
https://doi.org/10.1016/j.neubiorev.2013.06.007
https://doi.org/10.1016/j.neubiorev.2013.06.007
Publikováno v:
The Neuroscientist. 19:479-494
In psychiatric disorders, the effect of genetic and environmental factors may converge on molecular pathways and brain circuits related to growth factor functioning. In this review, we describe how disturbances in fibroblast growth factors (FGFs) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8494c46493ef55030e622b1302e9fb
https://doi.org/10.1177/1073858412472399
https://doi.org/10.1177/1073858412472399
Autor:
Teus H. Kappen, Jacobine E. Buizer-Voskamp, Eske M. Derks, K. van Eijk, M Neeleman, Jurjen J. Luykx, M van Amerongen, Jae Hoon Sul, Eric Strengman, Eskin E, Peter J M Keijzers, J. van Setten, Eef G.W.M. Lentjes, L Mentink, E P A van Dongen, S de Jong, P Borgdorff, Peter Bruins, Steven C. Bakker, Ake Tzu-Hui Lu, Rita M. Cantor, Joseph DeYoung, Roel A. Ophoff, René S. Kahn
Publikováno v:
Molecular psychiatry, 19(2), 228-234. Nature Publishing Group
Studying genetic determinants of intermediate phenotypes is a powerful tool to increase our understanding of genotype-phenotype correlations. Metabolic traits pertinent to the central nervous system (CNS) constitute a potentially informative target f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22325b5e787e6809f6085f5e900922b2
https://doi.org/10.1038/mp.2012.183
https://doi.org/10.1038/mp.2012.183
Autor:
Eef G.W.M. Lentjes, S de Jong, Roel A. Ophoff, P Borgdorff, L M Olde Loohuis, Steven C. Bakker, Jurjen J. Luykx, M Neeleman, René S. Kahn, E P A van Dongen, Peter Bruins, Steve Horvath, Eric Strengman
Publikováno v:
Translational Psychiatry
Translational Psychiatry [E], 6(12). Nature Publishing Group
Luykx, J J, Olde Loohuis, L M, Neeleman, M, Strengman, E, Bakker, S C, Lentjes, E, Borgdorff, P, van Dongen, E P A, Bruins, P, Kahn, R S, Horvath, S, de Jong, S & Ophoff, R A 2016, ' Peripheral blood gene expression profiles linked to monoamine metabolite levels in cerebrospinal fluid ', Translational psychiatry, vol. 6, no. 12, pp. e983 . https://doi.org/10.1038/tp.2016.245
Translational psychiatry, vol 6, iss 12
Translational Psychiatry [E], 6(12). Nature Publishing Group
Luykx, J J, Olde Loohuis, L M, Neeleman, M, Strengman, E, Bakker, S C, Lentjes, E, Borgdorff, P, van Dongen, E P A, Bruins, P, Kahn, R S, Horvath, S, de Jong, S & Ophoff, R A 2016, ' Peripheral blood gene expression profiles linked to monoamine metabolite levels in cerebrospinal fluid ', Translational psychiatry, vol. 6, no. 12, pp. e983 . https://doi.org/10.1038/tp.2016.245
Translational psychiatry, vol 6, iss 12
The blood–brain barrier separates circulating blood from the central nervous system (CNS). The scope of this barrier is not fully understood which limits our ability to relate biological measurements from peripheral to central phenotypes. For examp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a542d6908c6ffc79deb49244e6b821c9
https://pubmed.ncbi.nlm.nih.gov/27959337
https://pubmed.ncbi.nlm.nih.gov/27959337
Autor:
Steven C. Bakker, René S. Kahn, René C.W. Mandl, M.P. van den Heuvel, Marco P. Boks, Jurjen J. Luykx, K.G. Laban
Publikováno v:
Luykx, J J, Laban, K G, van den Heuvel, M P, Boks, M P M, Mandl, R C W, Kahn, R S & Bakker, S C 2012, ' Region and state specific glutamate downregulation in major depressive disorder : A meta-analysis of 1 H-MRS findings ', Neuroscience and Biobehavioral Reviews, vol. 36, no. 1, pp. 198-205 . https://doi.org/10.1016/j.neubiorev.2011.05.014
For major depressive disorder (MDD), magnetic resonance spectroscopy ( 1H-MRS) studies of glutamate, glutamine and Glx (the composite measure of mainly glutamate and glutamine) have yielded inconclusive or seemingly inconsistent results. We therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4713b3c2bac2cc34672f372dc5c588
https://doi.org/10.1016/j.neubiorev.2011.05.014
https://doi.org/10.1016/j.neubiorev.2011.05.014
Autor:
Anil P.S. Ori, Roel A. Ophoff, Joseph DeYoung, Teus H. Kappen, Nanda M. Verhoeven-Duif, Rita M. Cantor, Jacobine E. Buizer-Voskamp, J M den Heijer, Jae Hoon Sul, Eleazar Eskin, Wouter F. Visser, E P A van Dongen, P Borgdorff, E Pariama, Steven C. Bakker, Eric Strengman, Jurjen J. Luykx, Marco P. Boks, Peter Bruins, Jacob A. S. Vorstman, T. J. de Koning, René S. Kahn
Publikováno v:
Molecular Psychiatry, 20(12), 1557-1564. Nature Publishing Group
Molecular Psychiatry, 20(12), 1557. Nature Publishing Group
Molecular Psychiatry, 20(12), 1557. Nature Publishing Group
The N-methyl-d-aspartate receptor (NMDAR) coagonists glycine, d-serine and l-proline play crucial roles in NMDAR-dependent neurotransmission and are associated with a range of neuropsychiatric disorders. We conducted the first genome-wide association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3c309201c9573ece928c818977a497
https://research.rug.nl/en/publications/987f4814-48ca-4343-a25e-97735306d5ae
https://research.rug.nl/en/publications/987f4814-48ca-4343-a25e-97735306d5ae