Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Steven C Ratigan"'
Autor:
Thomas S. Corrigan, Leilani M. Lotti Diaz, Sarah E. Border, Steven C. Ratigan, Kayla Q. Kasper, Daniel Sojka, Pavla Fajtova, Conor R. Caffrey, Guy S. Salvesen, Craig A. McElroy, Christopher M. Hadad, Özlem Doğan Ekici
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1387-1402 (2020)
Aza-peptide aldehydes and ketones are a new class of reversible protease inhibitors that are specific for the proteasome and clan CD cysteine proteases. We designed and synthesised aza-Leu derivatives that were specific for the chymotrypsin-like acti
Externí odkaz:
https://doaj.org/article/31bf5971d3b54bc09b1c70a575cfb101
Autor:
Linsen Li, Steffen Lindert, Yanran Lu, Anna Chen, Jason E. Cummings, Chelsea A Mann, Sandip Vibhute, Brieanna Roth, Anthony English, Sheri Nolan, Mark J. Mitton-Fry, Daniel J. Wozniak, Steven C Ratigan, Richard A. Slayden, Jack C. Yalowich, Bryan Koci, Antony A. Okumu, Jonathan L. Papa, Craig A. McElroy, Justin T Seffernick, Leonard R Duncan
Publikováno v:
Journal of Medicinal Chemistry. 64:15214-15249
Novel bacterial topoisomerase inhibitors (NBTIs) are among the most promising new antibiotics in preclinical/clinical development. We previously reported dioxane-linked NBTIs with potent antistaphylococcal activity and reduced hERG inhibition, a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3892c880ddb3b3758eba4c921a02b47
https://doi.org/10.1021/acs.jmedchem.1c01250
https://doi.org/10.1021/acs.jmedchem.1c01250
Autor:
Yanran, Lu, Sandip, Vibhute, Linsen, Li, Antony, Okumu, Steven C, Ratigan, Sheri, Nolan, Jonathan L, Papa, Chelsea A, Mann, Anthony, English, Anna, Chen, Justin T, Seffernick, Bryan, Koci, Leonard R, Duncan, Brieanna, Roth, Jason E, Cummings, Richard A, Slayden, Steffen, Lindert, Craig A, McElroy, Daniel J, Wozniak, Jack, Yalowich, Mark J, Mitton-Fry
Publikováno v:
Journal of medicinal chemistry. 64(20)
Novel bacterial topoisomerase inhibitors (NBTIs) are among the most promising new antibiotics in preclinical/clinical development. We previously reported dioxane-linked NBTIs with potent antistaphylococcal activity and reduced hERG inhibition, a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc8f7442e2cb53241c3d17ad1ee5eb4c
https://pubmed.ncbi.nlm.nih.gov/34614347
https://pubmed.ncbi.nlm.nih.gov/34614347
Autor:
Thomas S, Corrigan, Leilani M, Lotti Diaz, Sarah E, Border, Steven C, Ratigan, Kayla Q, Kasper, Daniel, Sojka, Pavla, Fajtova, Conor R, Caffrey, Guy S, Salvesen, Craig A, McElroy, Christopher M, Hadad, Özlem, Doğan Ekici
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Aza-peptide aldehydes and ketones are a new class of reversible protease inhibitors that are specific for the proteasome and clan CD cysteine proteases. We designed and synthesised aza-Leu derivatives that were specific for the chymotrypsin-like acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03734a3adfd11bd8f1227f81054c3645
https://pubmed.ncbi.nlm.nih.gov/32633155
https://pubmed.ncbi.nlm.nih.gov/32633155
Autor:
Özlem Doğan Ekici, Craig A. McElroy, Steven C Ratigan, Conor R. Caffrey, Pavla Fajtová, Daniel Sojka, Christopher M. Hadad, Guy S. Salvesen, Leilani M Lotti Diaz, Sarah E. Border, Thomas Corrigan, Kayla Q Kasper
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1387-1402 (2020)
Aza-peptide aldehydes and ketones are a new class of reversible protease inhibitors that are specific for the proteasome and clan CD cysteine proteases. We designed and synthesised aza-Leu derivatives that were specific for the chymotrypsin-like acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13525f173b028429ea2742fff62aba5
Autor:
José A. Amaya, Job L. Grant, Olivia M. Manley, Courtney E. Wise, Steven C. Ratigan, Thomas M. Makris, Chun H. Hsieh
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 22:221-235
Increasing levels of energy consumption, dwindling resources, and environmental considerations have served as compelling motivations to explore renewable alternatives to petroleum-based fuels, including enzymatic routes for hydrocarbon synthesis. Phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c60f3847962f312e06ab3c153a359f
https://doi.org/10.1007/s00775-016-1425-0
https://doi.org/10.1007/s00775-016-1425-0