Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Steven C Perry"'
Autor:
Jasper J Visser, Yolanda Cheng, Steven C Perry, Andrew Benjamin Chastain, Bayan Parsa, Shatha S Masri, Thomas A Ray, Jeremy N Kay, Woj M Wojtowicz
Publikováno v:
eLife, Vol 4 (2015)
In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal subtypes organize their neurites into an intricate laminar structure that underlies visual processing. To find recognition proteins involved in lamination, we utilized microarray da
Externí odkaz:
https://doaj.org/article/97be02bc558f41a7916879d6407f93af
Autor:
Eric K Hoobler, Ganesha Rai, Andrew G S Warrilow, Steven C Perry, Christopher J Smyrniotis, Ajit Jadhav, Anton Simeonov, Josie E Parker, Diane E Kelly, David J Maloney, S L Kelly, Theodore R Holman
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65928 (2013)
We report the discovery of a novel dual inhibitor targeting fungal sterol 14α-demethylase (CYP51 or Erg11) and human 5-lipoxygenase (5-LOX) with improved potency against 5-LOX due to its reduction of the iron center by its phenylenediamine core. A s
Externí odkaz:
https://doaj.org/article/7993a077535548118bd36c4560fa1ddb
Autor:
Adriana Yamaguchi, Christopher vanHoorebeke, Benjamin E. Tourdot, Steven C. Perry, Grace Lee, Nicole Rhoads, Andrew Rickenberg, Abigail R. Green, James Sorrentino, Jennifer Yeung, J. Cody Freedman, Theodore R. Holman, Michael Holinstat
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract The antiplatelet effect of polyunsaturated fatty acids is primarily attributed to its metabolism to bioactive metabolites by oxygenases, such as lipoxygenases (LOX). Platelets have demonstrated the ability to generate 15‐LOX‐derived meta
Externí odkaz:
https://doaj.org/article/59a65c3dbd9846fcb9d48b2c506a8e61
Autor:
Steven C. Perry, Chakrapani Kalyanaraman, Benjamin E. Tourdot, William S. Conrad, Oluwayomi Akinkugbe, John Cody Freedman, Michael Holinstat, Matthew P. Jacobson, Theodore R. Holman
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 1087-1103 (2020)
The two oxylipins 7S,14S-dihydroxydocosahexaenoic acid (diHDHA) and 7S,17S-diHDHA [resolvin D5 (RvD5)] have been found in macrophages and infectious inflammatory exudates and are believed to function as specialized pro-resolving mediators (SPMs). The
Externí odkaz:
https://doaj.org/article/7347b4f4bdff49a38d8406855c419d2c
Autor:
Steven C. Perry, Christopher van Hoorebeke, James Sorrentino, Leslie Bautista, Oluwayomi Akinkugbe, William S. Conrad, Natalie Rutz, Theodore R. Holman
Publikováno v:
Archives of Biochemistry and Biophysics. 727:109317
Human 15-lipoxygenases (LOX) are critical enzymes in the inflammatory process, producing various pro-resolution molecules, such as lipoxins and resolvins, but the exact role each of the two 15-LOXs in these biosynthetic pathways remains elusive. Prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fc5b18febcd6de132a9cb311dc5416
https://doi.org/10.1016/j.abb.2022.109317
https://doi.org/10.1016/j.abb.2022.109317