Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Steven C Clifford"'
Autor:
Louise Hayes, Stephen Lowis, Faith Gibson, Sophie Thomas, Jenny Limond, Simon Bailey, Steven C Clifford, Sam Malins, Ray Owen, Ingram Wright, Heather Borrill, James Lemon
Publikováno v:
BMJ Open, Vol 11, Iss 6 (2021)
Introduction Survivors of childhood brain tumours have the poorest health-related quality of life of all cancer survivors due to the multiple physical and psychological sequelae of brain tumours and their treatment. Remotely delivered acceptance and
Externí odkaz:
https://doaj.org/article/1d5396a0b9744e6999b035e18f153fcd
Autor:
David R. Ghasemi, Konstantin Okonechnikov, Anne Rademacher, Stephan Tirier, Kendra K. Maass, Hanna Schumacher, Piyush Joshi, Maxwell P. Gold, Julia Sundheimer, Britta Statz, Ahmet S. Rifaioglu, Katharina Bauer, Sabrina Schumacher, Michele Bortolomeazzi, Felice Giangaspero, Kati J. Ernst, Steven C. Clifford, Julio Saez-Rodriguez, David T. W. Jones, Daisuke Kawauchi, Ernest Fraenkel, Jan-Philipp Mallm, Karsten Rippe, Andrey Korshunov, Stefan M. Pfister, Kristian W. Pajtler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Medulloblastomas with extensive nodularity are cerebellar tumors characterized by two distinct compartments and variable disease progression. The mechanisms governing the balance between proliferation and differentiation in MBEN remain poorl
Externí odkaz:
https://doaj.org/article/73c7a67e39074505ad2f97eb63756762
Autor:
David R. Ghasemi, Konstantin Okonechnikov, Anne Rademacher, Stephan Tirier, Kendra K. Maass, Hanna Schumacher, Piyush Joshi, Maxwell P. Gold, Julia Sundheimer, Britta Statz, Ahmet S. Rifaioglu, Katharina Bauer, Sabrina Schumacher, Michele Bortolomeazzi, Felice Giangaspero, Kati J. Ernst, Steven C. Clifford, Julio Saez-Rodriguez, David T. W. Jones, Daisuke Kawauchi, Ernest Fraenkel, Jan-Philipp Mallm, Karsten Rippe, Andrey Korshunov, Stefan M. Pfister, Kristian W. Pajtler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/47da4125f4844105ae9c15e274201e59
Autor:
Yuan Lu, Sarra L Ryan, David J Elliott, Graham R Bignell, P Andrew Futreal, David W Ellison, Simon Bailey, Steven C Clifford
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6159 (2009)
Medulloblastoma is the most common malignant brain tumour of childhood. The identification of critical genes involved in its pathogenesis will be central to advances in our understanding of its molecular basis, and the development of improved therape
Externí odkaz:
https://doaj.org/article/b41022fe00cc4ec689320bfc476e8694
Autor:
Marcel Kool, Jan Koster, Jens Bunt, Nancy E Hasselt, Arjan Lakeman, Peter van Sluis, Dirk Troost, Netteke Schouten-van Meeteren, Huib N Caron, Jacqueline Cloos, Alan Mrsić, Bauke Ylstra, Wieslawa Grajkowska, Wolfgang Hartmann, Torsten Pietsch, David Ellison, Steven C Clifford, Rogier Versteeg
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3088 (2008)
BackgroundMedulloblastoma is the most common malignant brain tumor in children. Despite recent improvements in cure rates, prediction of disease outcome remains a major challenge and survivors suffer from serious therapy-related side-effects. Recent
Externí odkaz:
https://doaj.org/article/85a9aa46f4a043bb939c4550eb28e806
Autor:
Claire Keeling, Simon Davies, Jack Goddard, Vijay Ramaswamy, Edward C. Schwalbe, Simon Bailey, Debbie Hicks, Steven C. Clifford
Publikováno v:
EClinicalMedicine, Vol 69, Iss , Pp 102469- (2024)
Summary: Background: Medulloblastoma patients with a sub-total surgical resection (STR; >1.5 cm2 primary tumour residuum post-surgery) typically receive intensified treatment. However, the association of STR with poor outcomes has not been observed c
Externí odkaz:
https://doaj.org/article/8aac62da82144c32925d2195f0158088
Autor:
Sarah Kohe, Christopher Bennett, Florence Burté, Magretta Adiamah, Heather Rose, Lara Worthington, Fatma Scerif, Lesley MacPherson, Simrandip Gill, Debbie Hicks, Edward C. Schwalbe, Stephen Crosier, Lisa Storer, Ambarasu Lourdusamy, Dipyan Mitra, Paul S. Morgan, Robert A. Dineen, Shivaram Avula, Barry Pizer, Martin Wilson, Nigel Davies, Daniel Tennant, Simon Bailey, Daniel Williamson, Theodoros N. Arvanitis, Richard G. Grundy, Steven C. Clifford, Andrew C. Peet
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104958- (2024)
Summary: Background: The malignant childhood brain tumour, medulloblastoma, is classified clinically into molecular groups which guide therapy. DNA-methylation profiling is the current classification ‘gold-standard’, typically delivered 3–4 wee
Externí odkaz:
https://doaj.org/article/7ea57b301d434c53922cf4908ce48606
Autor:
Jack Goddard, Jemma Castle, Emily Southworth, Anya Fletcher, Stephen Crosier, Idoia Martin-Guerrero, Miguel García-Ariza, Aurora Navajas, Julien Masliah-Planchon, Franck Bourdeaut, Christelle Dufour, Olivier Ayrault, Tobias Goschzik, Torsten Pietsch, Martin Sill, Stefan M. Pfister, Stefan Rutkowski, Stacey Richardson, Rebecca M. Hill, Daniel Williamson, Simon Bailey, Edward C. Schwalbe, Steven C. Clifford, Debbie Hicks
Publikováno v:
Acta Neuropathologica. 145:651-666
Group 4 tumours (MBGrp4) represent the majority of non-WNT/non-SHH medulloblastomas. Their clinical course is poorly predicted by current risk-factors. MBGrp4 molecular substructures have been identified (e.g. subgroups/cytogenetics/mutations), howev
Publikováno v:
Neuropathology and Applied Neurobiology. 49
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Resource Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f9e62c1e38cb49885bbd558c5c889e
https://doi.org/10.1158/0008-5472.22433306
https://doi.org/10.1158/0008-5472.22433306