Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Steven Buyske"'
Autor:
Ahmad Almelegy, Srujanesh Gunda, Steven Buyske, Marc Rosenbaum, Sepehr Sani, Mitra Afshari, Leo V. Metman, Christopher G. Goetz, Deborah Hall, M. Maral Mouradian, Gian Pal
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 899-904 (2024)
Abstract Objective Mutations in the glucocerebrosidase (GBA1) gene and subthalamic nucleus deep brain stimulation (STN‐DBS) are independently associated with cognitive dysfunction in persons with Parkinson's disease (PwP). We hypothesized that PwP
Externí odkaz:
https://doaj.org/article/3ca10e22374e402a83dbc53cebc9f07c
Autor:
Mohammad Yaser Anwar, Antoine R. Baldassari, Hannah G. Polikowsky, Colleen M. Sitlani, Heather M. Highland, Nathalie Chami, Hung-Hsin Chen, Mariaelisa Graff, Annie Green Howard, Su Yon Jung, Lauren E. Petty, Zhe Wang, Wanying Zhu, Steven Buyske, Iona Cheng, Robert Kaplan, Charles Kooperberg, Ruth J. F. Loos, Ulrike Peters, Joseph B. McCormick, Susan P. Fisher-Hoch, Christy L. Avery, Kira C. Taylor, Jennifer E. Below, Kari E. North
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-11 (2022)
Abstract Background Concurrent variation in adiposity and inflammation suggests potential shared functional pathways and pleiotropic disease underpinning. Yet, exploration of pleiotropy in the context of adiposity-inflammation has been scarce, and no
Externí odkaz:
https://doaj.org/article/7729e5f05bc64483af0e6d8c690b8ff2
Autor:
Chirayu Goswami, Michael Sheldon, Christian Bixby, Mehdi Keddache, Alexander Bogdanowicz, Yihe Wang, Jonathan Schultz, Jessica McDevitt, James LaPorta, Elaine Kwon, Steven Buyske, Dana Garbolino, Glenys Biloholowski, Alex Pastuszak, Mary Storella, Amit Bhalla, Florence Charlier-Rodriguez, Russ Hager, Robin Grimwood, Shareef A. Nahas
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background The Centers for Disease Control and Prevention contracted with laboratories to sequence the SARS-CoV-2 genome from positive samples across the United States to enable public health officials to investigate the impact of variants o
Externí odkaz:
https://doaj.org/article/e8bee7780dda4d538db015dfa1fe10c0
Autor:
Stephen A. Petrill, Brett G. Klamer, Steven Buyske, Erik G. Willcutt, Jeffrey R. Gruen, David J. Francis, Judy F. Flax, Linda M. Brzustowicz, Christopher W. Bartlett
Publikováno v:
Genes, Vol 14, Iss 9, p 1748 (2023)
Genetics researchers increasingly combine data across many sources to increase power and to conduct analyses that cross multiple individual studies. However, there is often a lack of alignment on outcome measures when the same constructs are examined
Externí odkaz:
https://doaj.org/article/88dc73a1b9b545edaae98e5f4a6b13b0
Autor:
Rohan Alibutud, Sammy Hansali, Xiaolong Cao, Anbo Zhou, Vaidhyanathan Mahaganapathy, Marco Azaro, Christine Gwin, Sherri Wilson, Steven Buyske, Christopher W. Bartlett, Judy F. Flax, Linda M. Brzustowicz, Jinchuan Xing
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13248 (2023)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by restrictive interests and/or repetitive behaviors and deficits in social interaction and communication. ASD is a multifactorial disease with a complex polygenic genetic
Externí odkaz:
https://doaj.org/article/29eeb67efafe49db96386d2d8d157780
Autor:
Tatiana Popovitchenko, Yongkyu Park, Nicholas F. Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D. Stephenson, Matthew L. Kraushar, Nicole L. Volk, Sejal M. Patel, H. R. Sagara Wijeratne, Diana Li, Kandarp S. Suthar, Aaron Wach, Miao Sun, Sebastian J. Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P. Hart, Mladen-Roko Rasin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Translational regulation of isoforms in the developing nervous system is not well understood. Here, the authors report translational de-repression of RNA binding protein isoforms at their 5′UTRs in the neocortex and show the neurodevelopmental risk
Externí odkaz:
https://doaj.org/article/26ec0393d8414ff985171a47ea4a1728
MicroRNA and MicroRNA-Target Variants Associated with Autism Spectrum Disorder and Related Disorders
Autor:
Anthony Wong, Anbo Zhou, Xiaolong Cao, Vaidhyanathan Mahaganapathy, Marco Azaro, Christine Gwin, Sherri Wilson, Steven Buyske, Christopher W. Bartlett, Judy F. Flax, Linda M. Brzustowicz, Jinchuan Xing
Publikováno v:
Genes, Vol 13, Iss 8, p 1329 (2022)
Autism spectrum disorder (ASD) is a childhood neurodevelopmental disorder with a complex and heterogeneous genetic etiology. MicroRNA (miRNA), a class of small non-coding RNAs, could regulate ASD risk genes post-transcriptionally and affect broad mol
Externí odkaz:
https://doaj.org/article/8bf91ef3f9234231b20510b0d2c90dab
Autor:
Linda M. Polfus, Burcu F. Darst, Heather Highland, Xin Sheng, Maggie C.Y. Ng, Jennifer E. Below, Lauren Petty, Stephanie Bien, Xueling Sim, Wei Wang, Pierre Fontanillas, Yesha Patel, Michael Preuss, Claudia Schurmann, Zhaohui Du, Yingchang Lu, Suhn K. Rhie, Joseph M. Mercader, Teresa Tusie-Luna, Clicerio González-Villalpando, Lorena Orozco, Cassandra N. Spracklen, Brian E. Cade, Richard A. Jensen, Meng Sun, Yoonjung Yoonie Joo, Ping An, Lisa R. Yanek, Lawrence F. Bielak, Salman Tajuddin, Aude Nicolas, Guanjie Chen, Laura Raffield, Xiuqing Guo, Wei-Min Chen, Girish N. Nadkarni, Mariaelisa Graff, Ran Tao, James S. Pankow, Martha Daviglus, Qibin Qi, Eric A. Boerwinkle, Simin Liu, Lawrence S. Phillips, Ulrike Peters, Chris Carlson, Lynne R. Wikens, Loic Le Marchand, Kari E. North, Steven Buyske, Charles Kooperberg, Ruth J.F. Loos, Daniel O. Stram, Christopher A. Haiman
Publikováno v:
HGG Advances, Vol 2, Iss 2, Pp 100029- (2021)
Summary: Genomic discovery and characterization of risk loci for type 2 diabetes (T2D) have been conducted primarily in individuals of European ancestry. We conducted a multiethnic genome-wide association study of T2D among 53,102 cases and 193,679 c
Externí odkaz:
https://doaj.org/article/dbef0a520b5d4bda84a828de1df9808d
Autor:
Yao Hu, Mariaelisa Graff, Jeffrey Haessler, Steven Buyske, Stephanie A Bien, Ran Tao, Heather M Highland, Katherine K Nishimura, Niha Zubair, Yingchang Lu, Marie Verbanck, Austin T Hilliard, Derek Klarin, Scott M Damrauer, Yuk-Lam Ho, VA Million Veteran Program, Peter W F Wilson, Kyong-Mi Chang, Philip S Tsao, Kelly Cho, Christopher J O'Donnell, Themistocles L Assimes, Lauren E Petty, Jennifer E Below, Ozan Dikilitas, Daniel J Schaid, Matthew L Kosel, Iftikhar J Kullo, Laura J Rasmussen-Torvik, Gail P Jarvik, Qiping Feng, Wei-Qi Wei, Eric B Larson, Frank D Mentch, Berta Almoguera, Patrick M Sleiman, Laura M Raffield, Adolfo Correa, Lisa W Martin, Martha Daviglus, Tara C Matise, Jose Luis Ambite, Christopher S Carlson, Ron Do, Ruth J F Loos, Lynne R Wilkens, Loic Le Marchand, Chris Haiman, Daniel O Stram, Lucia A Hindorff, Kari E North, Charles Kooperberg, Iona Cheng, Ulrike Peters
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008684 (2020)
Lipid levels are important markers for the development of cardio-metabolic diseases. Although hundreds of associated loci have been identified through genetic association studies, the contribution of genetic factors to variation in lipids is not full
Externí odkaz:
https://doaj.org/article/ca40beb39a0e40c49b79df873ea4e1d6
Autor:
Bridget M. Lin, Girish N. Nadkarni, Ran Tao, Mariaelisa Graff, Myriam Fornage, Steven Buyske, Tara C. Matise, Heather M. Highland, Lynne R. Wilkens, Christopher S. Carlson, S. Lani Park, V. Wendy Setiawan, Jose Luis Ambite, Gerardo Heiss, Eric Boerwinkle, Dan-Yu Lin, Andrew P. Morris, Ruth J. F. Loos, Charles Kooperberg, Kari E. North, Christina L. Wassel, Nora Franceschini
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
BackgroundChronic kidney disease (CKD) is common and disproportionally burdens United States ethnic minorities. Its genetic determinants may differ by disease severity and clinical stages. To uncover genetic factors associated CKD severity among high
Externí odkaz:
https://doaj.org/article/7ba2ad342bb444b5b8f804c4305a9533