Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Steven Bochnowicz"'
Autor:
David C. Underwood, Steven Bochnowicz, Ruth R. Osborn, Calvert Louden, Timothy K. Hart, Eliot H. Ohlstein, Douglas W. P. Hay
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:S453-S455
The cardiopulmonary profile of three different rat strains was compared after exposure to hypoxia (9% O2) for 0, 7, or 14 days. In Sprague-Dawley (SD), Wistar (W), and high altitude-sensitive (HAS) rats, pulmonary arterial pressure (PAP) rose 30, 58,
Autor:
Anne M. Romanic, Steven Bochnowicz, Edward F. Webb, John C. Lee, Don E. Griswold, Douglas W. P. Hay, David C. Underwood, Ruth R. Osborn, David J. Rieman, Jerry L. Adams
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 279(5)
The effects of a second generation p38 mitogen-activated protein kinase (MAPK) inhibitor, SB 239063 [ trans-1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyridimidin-4-yl)imidazole; IC50 = 44 nM vs. p38α], were assessed in models that repre
Autor:
Ruth R. Osborn, Calvert Louden, Tim Hart, Douglas W. P. Hay, David C. Underwood, Steven Bochnowicz, Mark A. Luttmann
Publikováno v:
Clinical and experimental hypertension (New York, N.Y. : 1993). 22(5)
The cardiopulmonary profile of three rat strains (Sprague-Dawley, Wistar and High altitude-sensitive) was compared upon exposure to hypoxia (9% O2) for 0, 7 or 14 days. No differences were observed among the in vitro contractile (ET-1) and relaxant (
Autor:
C.S. Louden, T.K. Hart, D.C. Underwood, Douglas W. P. Hay, R.R. Osborn, Steven Bochnowicz, J.D. Elliott, Mark A. Luttmann
Publikováno v:
Pulmonary pharmacologytherapeutics. 12(1)
The effects of SB 217242, a non-peptide endothelin (ET) receptor antagonist, were investigated against hypoxia-induced cardiopulmonary changes in high altitude-sensitive rats. In isolated pulmonary artery rings, SB 217242 (30 n m ) antagonized ET-1-i
Publikováno v:
Laboratory animals. 31(4)
Prolonged exposure to hypoxia elicits a variety of time-related morphologic and physiologic changes in the pulmonary vasculature of mammals, including humans. The study of hypoxia-induced changes in rodents generally requires a prolonged exposure to
Autor:
Lavonne D. Meunier, R. R. Osborn, David C. Underwood, Linda B. Novak, Jane K. Matthews, Steven Bochnowicz
Publikováno v:
International archives of allergy and immunology. 109(3)
The aim of the present study was to analyze the increased airway reactivity to antigen induced by beta-adrenoceptor blockade, adrenalectomy or medullectomy and to assess the contribution of circulating catecholamines to the increased reactivity. In a
Autor:
David C. Underwood, Theodore J. Torphy, D.W.P. Hay, S. J. Newsholme, R. R. Osborn, Steven Bochnowicz
Publikováno v:
Journal of Allergy and Clinical Immunology. 97:289-289