Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Steven Bentivegna"'
Autor:
Smitha S. Krishnamurthi, Patricia LoRusso, Steven Bentivegna, Alejandro D. Ricart, Samuel E. DePrimo, John J. Rinehart, Weiwei Tan, Lisa Malburg, Keith D. Wilner, Paul B. Chapman, Lisle Nabell
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 16(6)
Purpose: To determine tolerability, pharmacokinetics, and pharmacodynamics of PD-0325901, a highly potent, selective, oral mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase 1/2 inhibitor in advanced cancer patients.
Autor:
Zhiyong Wang, Jianbiao Zheng, Albert B. Seymour, Adam Pavlicek, Steven Bentivegna, Malek Faham, Martin Moorhead, Eugeni Namsaraev, Kent Suyenaga, Victoria Carlton, Thomas D. Willis, Liana Lee, James S. Ireland, Farooq Siddiqui
Publikováno v:
Human mutation. 29(3)
Mismatch repair detection (MRD) was used to screen 93 matched tumor-normal sample pairs and 22 cell lines for somatic mutations in 30 cancer relevant genes. Using a starting amount of only 150 ng of genomic DNA, we screened 102 kb of sequence for som
Autor:
Antonio Gualberto, Albert B. Seymour, Steven Bentivegna, Jennifer M. Reynolds, Gary Borzillo, David B. Lloyd
Publikováno v:
Molecular Cancer Therapeutics. 8:B119-B119
To test the hypothesis that mutant insulin-like growth factor 1 receptor (IGF-1R) protein may differentially respond to inhibition by figitumumab (CP-751, 871), potentially necessitating patient screening, we studied the in vitro efficacy of figitumu