Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Steven Bensinger"'
Autor:
Sonia Sharma, Ian Mathews, John T Chang, Ananda Goldrath, Maximilian Heeg, Quynhanh Nguyen, Mohit Jain, Max Krummel, Miguel Reina Campos, Kelly Kennewick, Giovanni Galletti, Vida Luna, Hongling Huang, Justin Milner, Kenneth Hu, Amy Vichaidit, Natalie Santillano, Brigid Boland, Hongbo Chi, Steven Bensinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d96a5c57683f40f7a144645f05ee0f34
Autor:
Pallavi Mukherjee, Greg Hough, Arnab Chattopadhyay, Mohamad Navab, Hannah R. Fogelman, David Meriwether, Kevin Williams, Steven Bensinger, Travis Moller, Kym F. Faull, Aldons J. Lusis, M. Luisa Iruela-Arispe, Kristina I. Bostrom, Peter Tontonoz, Srinivasa T. Reddy, Alan M. Fogelman
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 8, Pp 1636-1647 (2017)
Feeding LDL receptor (LDLR)-null mice a Western diet (WD) increased the expression of IFN-β in jejunum as determined by quantitative RT-PCR (RT-qPCR), immunohistochemistry (IHC), and ELISA (all P < 0.0001). WD also increased the expression of choles
Externí odkaz:
https://doaj.org/article/75de2f787cb5457d800af42d09707286
Autor:
Matthew Krummel, Catherine Blish, Michael Kuhns, Ken Cadwell, Andrew Oberst, Ananda Goldrath, K. Mark Ansel, Hongbo Chi, Ryan O’Connell, E. John Wherry, Marion Pepper, Igor Brodsky, John Chang, Joseph R. Arron, Nick Haining, Deepta Bhattacharya, Mark Anderson, Carla V. Rothlin, Susan Schwab, Yasmine Belkaid, Ari Molofsky, Pete Savage, Daniel Mucida, Akiko Iwasaki, Gabriel Victora, Jessica Hamerman, David Masopust, Greg Barton, Susan Kaech, Prescott Woodruff, Daniel B. Stetson, Tiffany C. Scharschmidt, Ross Kedl, Elina Isabel Zúñiga, Alexander Hoffmann, Matt Williams, Katrin D. Mayer-Barber, Sunny Shin, Steven Bensinger, Li-Fan Lu, Mark Looney, June L. Round, Sebastian Amigorena, Jonathan Yewdell, Joseph Sun, John T. Harty
Publikováno v:
Cell. 179(7)
Despite being a staple of our science, the process of pre-publication peer review has few agreed-upon standards defining its goals or ideal execution. As a community of reviewers and authors, we assembled an evaluation format and associated specific
Autor:
Minsub S Lee, Quan Zhou, Xun Chi, Wei Yuan Hsieh, An-Chieh Fang, Philip O. Scumpia, Kevin Williams, Robert Damoiseaux, Steven Bensinger
Publikováno v:
The Journal of Immunology. 204:67.37-67.37
Macrophages undergo profound metabolic reprogramming in response to activation signals. However, the purpose and the mechanism of this reprogramming remains poorly understood. Cholesterol is an essential lipid molecule that modulates biochemical and
Rapid transcriptional reprogramming of the lipid biosynthesis genes in response to type I interferon
Autor:
Autumn Gabrielle York, Kevin J. Williams, Xin Liu, Joseph P. Argus, Ann-Jay Tong, Quan D. Zhou, Stephen T Smale, Steven Bensinger
Publikováno v:
The Journal of Immunology. 196:202.14-202.14
Cellular lipid requirements are achieved through a combination of biosynthesis and import programs. In previous studies, we found that type I interferon (IFN) signaling shifts the balance of these programs by decreasing synthesis and increasing impor
Autor:
Autumn York, Ann-Jay Tong, Joseph Argus, Elizabeth Gray, Nicholas Wu, Anjie Zhen, Scott Kitchen, Stephen Smale, Daniel Stetson, Steven Bensinger
Publikováno v:
The Journal of Immunology. 194:126.2-126.2
Pathogen invasion alters host lipid metabolism, however the mechanisms underlying this remain poorly understood. Here, we show that transcriptional repression of cholesterol and fatty acid biosynthesis is driven by TRIF-dependent danger signals. Unex
Publikováno v:
The Journal of Immunology. 192:123.9-123.9
Oxysterols, or oxidized derivatives of cholesterol, have emerged as important regulators of adaptive and innate immunity. However, the molecular mechanisms by which these lipids facilitate host defense remain indeterminate. To better understand how c
Autor:
Yoko Kidani, Heidi Elsaesser, M. Hock, Laurent Vergnes, Kevin Williams, Joseph Argus, Beth Marbois, Evangelia Komisopoulou, Elizabeth Wilson, Timothy Osborne, Thomas Graeber, Karen Reue, David Brooks, Steven Bensinger
Publikováno v:
The Journal of Immunology. 190:64.15-64.15
A hallmark of the adaptive immune system is the ability of CD8 T cells to undergo rapid clonal expansion in response to antigenic stimulation. To meet the biosynthetic requirements of rapid growth and proliferation, effector T cells must reprogram th
Autor:
Steven Bensinger, Yoko Kidani, M. Benjamin Hock, Joseph Argus, Evangelia Komisopoulou, Thomas Graeber
Publikováno v:
The Journal of Immunology. 188:47.17-47.17
Accumulating evidence indicates that cellular metabolism is an important regulator of T cell immunity. We and others have shown that activation of T cell rapidly initiates a robust genetic and biochemical program that drives the biosynthesis of lipid