Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Steven Bassnett"'
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 19, Iss , Pp 100756- (2020)
Externí odkaz:
https://doaj.org/article/2bd590ed8839458999e85702e77f0d67
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 1 (2019)
Fibrillin is an evolutionarily ancient protein that lends elasticity and resiliency to a variety of tissues. In humans, mutations in fibrillin-1 cause Marfan and related syndromes, conditions in which the eye is often severely affected. To gain insig
Externí odkaz:
https://doaj.org/article/5da8c414ac02403ca0a7b8c73a136cca
Autor:
Frans Vinberg, Tian Wang, Alicia De Maria, Haiqing Zhao, Steven Bassnett, Jeannie Chen, Vladimir J Kefalov
Publikováno v:
eLife, Vol 6 (2017)
Calcium (Ca2+) plays an important role in the function and health of neurons. In vertebrate cone photoreceptors, Ca2+ controls photoresponse sensitivity, kinetics, and light adaptation. Despite the critical role of Ca2+ in supporting the function and
Externí odkaz:
https://doaj.org/article/ad538ebe229e424b9158b207f06f95da
Publikováno v:
Royal Society Open Science, Vol 4, Iss 1 (2017)
The mathematical determinants of vertebrate organ growth have yet to be elucidated fully. Here, we utilized empirical measurements and a dynamic branching process-based model to examine the growth of a simple organ system, the mouse lens, from E14.5
Externí odkaz:
https://doaj.org/article/a4203175df8b4341b6fee05bdd5d6d17
Publikováno v:
J Vis Exp
Elasticity is essential to the function of tissues such as blood vessels, muscles, and lungs. This property is derived mostly from the extracellular matrix (ECM), the protein meshwork that binds cells and tissues together. How the elastic properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf24fdb78c9af3330d4dbabf25c2424
https://doi.org/10.3791/63171-v
https://doi.org/10.3791/63171-v
Autor:
Steven Bassnett
Publikováno v:
Prog Retin Eye Res
The Zonule of Zinn, or ciliary zonule, is the elaborate system of extracellular fibers that centers the lens in the eye. In humans, the fibers transmit forces that flatten the lens during the process of disaccommodation, thereby bringing distant obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aca20a0ba2d37fca57ec08ec03ee7d
https://pubmed.ncbi.nlm.nih.gov/32980533
https://pubmed.ncbi.nlm.nih.gov/32980533
Autor:
Robert P. Mecham, Steven Bassnett, Heena Kumra, Mark Gibson, W. Beatty, Wendell Jones, Yanrong Shi, Matthew Aaron Reilly, Q. Tan, Dieter P. Reinhardt, Juan Rodriguez
Publikováno v:
Matrix Biol
Latent-transforming growth factor beta-binding protein 2 (LTBP-2) is a major component of arterial and lung tissue and of the ciliary zonule, the system of extracellular fibers that centers and suspends the lens in the eye. LTBP-2 has been implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8671035f45a39569ce0aac9eac4bcaa
https://pubmed.ncbi.nlm.nih.gov/33039488
https://pubmed.ncbi.nlm.nih.gov/33039488
Publikováno v:
Experimental Eye Research. 167:18-24
Loss of intracellular calcium homeostasis may contribute to the opacification of lens tissue during cortical cataract formation. In healthy lenses, the concentration of intracellular calcium is maintained at levels far below electrochemical equilibri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f794848a99a0ace44c7f1f0b8702c1
https://doi.org/10.1016/j.exer.2017.11.002
https://doi.org/10.1016/j.exer.2017.11.002
Autor:
J.C. Youkilis, Steven Bassnett
Publikováno v:
Experimental Eye Research. 213:108811
The ciliary epithelium plays a central role in ocular homeostasis but cells of the pigmented and non-pigmented layers are difficult to isolate physically and study. Here we used single-cell RNA-sequencing (scRNA-seq) to analyze the transcriptional si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e791c1d4b9112eb8e09d633a90d0af
https://doi.org/10.1016/j.exer.2021.108811
https://doi.org/10.1016/j.exer.2021.108811
Autor:
Steven Bassnett, M. Joseph Costello
Publikováno v:
Experimental Eye Research. 156:50-57
Fiber cells of the ocular lens are arranged in a series of concentric shells. New growth shells are added continuously to the lens surface and, as a consequence, the preexisting shells are buried. To focus light, the refractive index of the lens cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1ce0cf508ef90e40d6669003368e42
https://doi.org/10.1016/j.exer.2016.03.009
https://doi.org/10.1016/j.exer.2016.03.009