Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Steven B. Symington"'
Autor:
Steven B. Symington, Natasha Catlin
Publikováno v:
Impulse: The Premier Undergraduate Neuroscience Journal, p 1 (2009)
The goal of this study was to determine the effect of deltamethrin, a pyrethroid insecticide, on CaV3.2, a human T-type voltage-sensitive calcium channel expressed in Xenopus laevis (X.laevis) oocytes. Cav3.2 cDNA was transcribed into cRNA; the cRNA
Externí odkaz:
https://doaj.org/article/cd8b7c75c993486c961eabbf7aaadcdc
Publikováno v:
Pesticide Biochemistry and Physiology. 189:105296
Microtransplantation of neurolemma tissue fragments from mammalian brain into the plasma membrane of Xenopus laevis oocytes is a tool to examine the endogenous structure and function of various ion channels and receptors associated with the central n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1ce2cf7ff99074f570d99faa998910
https://doi.org/10.1016/j.pestbp.2022.105296
https://doi.org/10.1016/j.pestbp.2022.105296
Publikováno v:
Food and Chemical Toxicology. 160:112804
A significant rise in the incidence of obesity and type 2 diabetes has occurred worldwide in the last two decades. Concurrently, a growing body of evidence suggests a connection between exposure to environmental pollutants, particularly insecticides,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e8a49e1e942b4441f48873bf9e68ef
https://doi.org/10.1016/j.fct.2021.112804
https://doi.org/10.1016/j.fct.2021.112804
Publikováno v:
Food and Chemical Toxicology. 121:387-395
Permethrin is a pyrethroid insecticide that acts thru membrane depolarization and is known to disrupt calcium levels in neurons. Disrupted calcium homeostasis is linked to oxidative stress as well as many other cellular mis-functions and permethrin h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422043a3494bf060d223c0a1d509d9c5
https://doi.org/10.1016/j.fct.2018.09.009
https://doi.org/10.1016/j.fct.2018.09.009
Publikováno v:
NeuroToxicology. 60:260-273
Microtransplantation of mammalian brain neurolemma into the plasma membrane of Xenopus oocytes is used to study ion channels in their native form as they appear in the central nervous system. Use of microtransplanted neurolemma is advantageous for va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93a4d7966be198fd2d3041f3c74ed48
https://doi.org/10.1016/j.neuro.2016.04.004
https://doi.org/10.1016/j.neuro.2016.04.004
Autor:
Aaron D. Gross, Yoshihisa Ozoe, Joel R. Coats, Thomas C. Sparks, Beth A. Lorsbach, David M. Soderlund, Steven B. Symington, Edwin Murenzi, Abigail C. Toltin, David Lansky, J. Marshall Clark, T. Cens, M. Rousset, J-B. Thibaud, C. Menard, C. Collet, M. Chahine, P. Charnet, T. L. Calkins, P. M. Piermarini, Rafique Islam, Jeffrey R. Bloomquist, S. Furutani, M. Ihara, K. Kai, H. Hayashi, K. Matsuda
Publikováno v:
ACS Symposium Series ISBN: 9780841232570
ACS Symposium Series
ACS Symposium Series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989f4332174b2d5e5b5c3b6e48c13281
https://doi.org/10.1021/bk-2017-1264.ch004
https://doi.org/10.1021/bk-2017-1264.ch004
Publikováno v:
Pesticide Biochemistry and Physiology. 99:131-139
Isolated rat brain synaptosomes were used to evaluate the action of pyrethroid mixtures on Ca 2+ influx and subsequent glutamate release under depolarizing conditions. In equipotent binary mixtures at their respective and/or estimated EC 50 s with de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cf7c0552cd3f1d4bb57fe30fc0927a7
https://doi.org/10.1016/j.pestbp.2010.11.009
https://doi.org/10.1016/j.pestbp.2010.11.009
Publikováno v:
Pesticide Biochemistry and Physiology. 97:101-108
Voltage clamp electrophysiological studies using wild type Ca V 2.2 and its β 3 subunit coexpressed in Xenopus oocytes revealed that deltamethrin increased the rate of activation, prolonged inactivation and reduced peak current. Site-directed mutage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c1c1dbfd5689421cd5aa8cd3a5072e5
https://doi.org/10.1016/j.pestbp.2009.06.007
https://doi.org/10.1016/j.pestbp.2009.06.007
Characterization of 11 commercial pyrethroids on the functional attributes of rat brain synaptosomes
Publikováno v:
Pesticide Biochemistry and Physiology. 92:61-69
The action of 11 commercial pyrethroids on Ca 2+ influx and glutamate release was assessed using high-throughput functional assays with rat brain synaptosomes to better understand the mechanistic nature of pyrethroid-induced neurotoxicity and aid in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4710cb2417ab6358539c5ec5b50e54f
https://doi.org/10.1016/j.pestbp.2008.06.009
https://doi.org/10.1016/j.pestbp.2008.06.009