Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Steven B. Mwakalinga"'
Autor:
Franklin W. Mosha, Reginald A. Kavishe, Grace Kinabo, Adonira Saro, Debora C. Kajeguka, Kaunara A. Azizi, Steven B. Mwakalinga, Michael Alifrangis
Background There are several unknown illnesses including chikungunya and dengue viruses that present with fever in children. Therefore there are many cases that are misdiagnosed. Consequently we performed a study to determine the clinical characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fac98e7da9e3826baf212f7c8e8b2a24
https://doi.org/10.21203/rs.3.rs-22979/v1
https://doi.org/10.21203/rs.3.rs-22979/v1
Autor:
Louise Turner, Christian W Wang, Thomas Lavstsen, Steven B Mwakalinga, Robert W Sauerwein, Cornelus C Hermsen, Thor G Theander
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29025 (2011)
Antibodies to polymorphic antigens expressed during the parasites erythrocytic stages are important mediators of protective immunity against P. falciparum malaria. Therefore, polymorphic blood stage antigens like MSP3, EBA-175 and GLURP and variant s
Externí odkaz:
https://doaj.org/article/4ff7e00fb58e43c6852f702c5688dc63
Autor:
Steven B. Mwakalinga, Sixbert I. Mkumbaye, Reginald A. Kavishe, Eric Lyimo, John Lusingu, Christian W. Wang, Jakob S. Jespersen, Daniel T. R. Minja, Thomas Lavstsen, Jacklin F. Mosha, Alphaxard Manjurano, Thor G. Theander
By attaching infected erythrocytes to the vascular lining, Plasmodium falciparum parasites leave blood circulation and avoid splenic clearance. This sequestration is central to pathogenesis. Severe malaria is associated with parasites expressing an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c012b951afd34abe41c2f59be302c80
https://europepmc.org/articles/PMC5364309/
https://europepmc.org/articles/PMC5364309/
Autor:
Thor G. Theander, Thomas Lavstsen, Daniel T. R. Minja, Jakob S. Jespersen, Christian W. Wang, Steven B. Mwakalinga, Michael Alifrangis, Sixbert I. Mkumbaye, John Lusingu, Reginald A. Kavishe
Publikováno v:
Mkumbaye, S I, Minja, D T R, Jespersen, J S, Alifrangis, M, Kavishe, R A, Mwakalinga, S B, Lusingu, J P, Theander, T G, Lavstsen, T & Wang, C W 2017, ' Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites ', Malaria Journal, vol. 16, no. 1, 69 . https://doi.org/10.1186/s12936-017-1714-2
Malaria Journal
Malaria Journal
Background Establishing in vitro Plasmodium falciparum culture lines from patient parasite isolates can offer deeper understanding of geographic variations of drug sensitivity and mechanisms of malaria pathogenesis and immunity. Cellulose column filt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f07824ac1913d14914a4e60eb27af3b1
https://curis.ku.dk/portal/da/publications/cellulose-filtration-of-blood-from-malaria-patients-for-improving-ex-vivo-growth-of-plasmodium-falciparum-parasites(e960d311-4ef5-4d00-bfa7-c3d163bcead5).html
https://curis.ku.dk/portal/da/publications/cellulose-filtration-of-blood-from-malaria-patients-for-improving-ex-vivo-growth-of-plasmodium-falciparum-parasites(e960d311-4ef5-4d00-bfa7-c3d163bcead5).html
Autor:
Steven B. Mwakalinga, Christian W. Wang, Jens E.V. Petersen, John Lusingu, Sixbert I. Mkumbaye, Eric Lyimo, Alphaxard Manjurano, Thor G. Theander, Jacklin F. Mosha, Anna V. Vaaben, Thomas Lavstsen, Daniel T. R. Minja, Reginald A. Kavishe
Publikováno v:
Scientific Reports
Petersen, J E V, Mkumbaye, S I, Vaaben, A V, Manjurano, A, Lyimo, E, Kavishe, R A, Mwakalinga, S B, Mosha, J, Minja, D T R, Lusingu, J P A, Theander, T G, Lavstsen, T & Wang, C W 2016, ' Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1 ', Scientific Reports, vol. 6, 35950 . https://doi.org/10.1038/srep35950
Petersen, J E V, Mkumbaye, S I, Vaaben, A V, Manjurano, A, Lyimo, E, Kavishe, R A, Mwakalinga, S B, Mosha, J, Minja, D T R, Lusingu, J P A, Theander, T G, Lavstsen, T & Wang, C W 2016, ' Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1 ', Scientific Reports, vol. 6, 35950 . https://doi.org/10.1038/srep35950
The pathogenesis of Plasmodium falciparum malaria involves a complex interplay between parasite adhesion and inflammatory response that includes release of cytokines and activation of the endothelium with accompanying release of Angiopoitin 2 (Ang2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579dedcaba13ed52563145881ae87fdb
Autor:
Steven B. Mwakalinga, Hassan Mattaka, Fatuma Makuka, Maulilio John Kipanyula, Alphaxard Manjurano
Publikováno v:
Tanzania Journal of Health Research; Vol 18, No 3 (2016)
Streptococcal pharyngitis continues to be one of the most common childhood illnesses throughout the world. Recent evidence indicates an increased incidence of group A Streptococcal (GAS) infections, which is a significant cause of mortality and morbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8944c31d672951d59355b2c29408af60
https://www.ajol.info/index.php/thrb/article/view/133200
https://www.ajol.info/index.php/thrb/article/view/133200
Autor:
John G. Mrema, Janet Sabuni, Debora C. Kajeguka, Steven B. Mwakalinga, Maseke R. Mgabo, Gwakisa Ngasala
Publikováno v:
Tanzania Journal of Health Research; Vol 18, No 1 (2016)
Background: Oral candidiasis has been a global health challenge especially in immunocompromised patients particularly with HIV infection. Though the incidence and prevalence of opportunistic infections have been reduced due to the use of anti-retrovi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009cc24553e4f9564531b7f055e12566
https://www.ajol.info/index.php/thrb/article/view/118557
https://www.ajol.info/index.php/thrb/article/view/118557
Autor:
Karin L. Schiøler, Rogathe Ndossi, Arnold Ndaro, Steven B. Mwakalinga, Franklin W. Mosha, Debora C. Kajeguka, Jaffu Chilongola, Michael Alifrangis, Robert Kaaya, Reginald A. Kavishe
Publikováno v:
BMC Infectious Diseases
Kajeguka, D C, Kaaya, R D, Mwakalinga, S, Ndossi, R, Ndaro, A, Chilongola, J O, Mosha, F W, Schiøler, K L, Kavishe, R A & Alifrangis, M 2016, ' Prevalence of dengue and chikungunya virus infections in north-eastern Tanzania : a cross sectional study among participants presenting with malaria-like symptoms ', B M C Infectious Diseases, vol. 16, no. 1, 183 . https://doi.org/10.1186/s12879-016-1511-5
Kajeguka, D C, Kaaya, R D, Mwakalinga, S, Ndossi, R, Ndaro, A, Chilongola, J O, Mosha, F W, Schiøler, K L, Kavishe, R A & Alifrangis, M 2016, ' Prevalence of dengue and chikungunya virus infections in north-eastern Tanzania : a cross sectional study among participants presenting with malaria-like symptoms ', B M C Infectious Diseases, vol. 16, no. 1, 183 . https://doi.org/10.1186/s12879-016-1511-5
Background In spite of increasing reports of dengue and chikungunya activity in Tanzania, limited research has been done to document the general epidemiology of dengue and chikungunya in the country. This study aimed at determining the sero-prevalenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c9299805883bd2590040c678d07f1d
https://pubmed.ncbi.nlm.nih.gov/27112553
https://pubmed.ncbi.nlm.nih.gov/27112553
Autor:
Mafalda Resende, Lars Hviid, Madeleine Dahlbäck, Morten Nielsen, Thor G. Theander, John Lusingu, Nicaise Tuikue Ndam, Steven B. Mwakalinga, Ali Salanti, Pamela Magistrado
Publikováno v:
The Journal of Infectious Diseases. 198:1071-1074
Malaria remains a major threat, in sub-Saharan Africa primarily, and the most deadly infections are those with Plasmodium falciparum. Pregnancy-associated malaria is a clinically important complication of infection; it results from a unique interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57df599576fd06cc93d352283173bbc
https://doi.org/10.1086/591502
https://doi.org/10.1086/591502
Autor:
David E. Arnot, Thomas Lavstsen, John Lusingu, Louise Turner, Thor G. Theander, Christian W. Wang, Bismarck Dinko, Dominique C Bengtsson, Colin J. Sutherland, Steven B. Mwakalinga
Publikováno v:
Malaria Journal, Vol 11, Iss 1, p 429 (2012)
Mwakalinga, S B, Wang, C W, Bengtsson, D C, Turner, L, Dinko, B, Lusingu, J P, Arnot, D E, Sutherland, C J, Theander, T G & Lavstsen, T 2012, ' Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes ', Malaria Journal, vol. 11, no. 429, pp.-. https://doi.org/10.1186/1475-2875-11-429
Malaria Journal
Mwakalinga, S B, Wang, C W, Bengtsson, D C, Turner, L, Dinko, B, Lusingu, J P, Arnot, D E, Sutherland, C J, Theander, T G & Lavstsen, T 2012, ' Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes ', Malaria Journal, vol. 11, no. 429, pp.-. https://doi.org/10.1186/1475-2875-11-429
Malaria Journal
Background The ability of Plasmodium falciparum to undergo antigenic variation, by switching expression among protein variants encoded by multigene families, such as var, rif and stevor, is key to the survival of this parasite in the human host. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d50b729b3e104dacb4ec9f70fd0c67
http://www.malariajournal.com/content/11/1/429
http://www.malariajournal.com/content/11/1/429