Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Steven B. Mizel"'
Autor:
Kanwaldeep Bajwa, Steven B. Mizel, Ryan C. May, Sharon E. Frey, Kathleen R. Lottenbach, Irene Graham, Robert B. Belshe, Aaron H. Graff, Edwin L. Anderson
Publikováno v:
Vaccine. 35:6759-6765
Introduction Intentional aerosolization of Yersinia pestis may result in pneumonic plague which is highly fatal if not treated early. Methods We conducted a phase 1 randomized, double blind (within each group), placebo controlled, dose escalation tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a611db6ae7cc6301e26cc7dc98f188
https://doi.org/10.1016/j.vaccine.2017.09.070
https://doi.org/10.1016/j.vaccine.2017.09.070
Publikováno v:
Virology. 419(2):97-106
To test the potential for parainfluenza virus 5 (PIV5)-based vectors to provide protection from vaccinia virus (VACV) infection, PIV5 was engineered to express secreted VACV L1R and B5R proteins, two important antigens for neutralization of intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c3962328d7c9ac8b9eb6255a701c0f
Publikováno v:
The Journal of Immunology. 186:6255-6262
Flagellin is a highly effective adjuvant for CD4+ T cell and humoral immune responses. However, there is conflicting data in the literature regarding the ability of flagellin to promote a CD8+ T cell response. In this article, we report that immuniza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c9aa39e57f3d1333616f9916340e94
https://doi.org/10.4049/jimmunol.1001855
https://doi.org/10.4049/jimmunol.1001855
Autor:
John T. Bates, Steven B. Mizel
Publikováno v:
The Journal of Immunology. 185:5677-5682
Flagellin is a potent activator of a broad range of cell types involved in innate and adaptive immunity. An increasing number of studies have demonstrated the effectiveness of flagellin as an adjuvant, as well as its ability to promote cytokine produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae247e56e119f4253f9ff461082a8bc
https://doi.org/10.4049/jimmunol.1002156
https://doi.org/10.4049/jimmunol.1002156
Publikováno v:
Journal of Virology. 84:3552-3561
Recombinant vesicular stomatitis viruses (VSV) are excellent candidate vectors for vaccination against human diseases. The neurovirulence of VSV in animal models requires the attenuation of the virus for use in humans. Previous efforts have focused o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057b526ee26f7a37470c8efbd02746ff
https://doi.org/10.1128/jvi.01572-09
https://doi.org/10.1128/jvi.01572-09
Publikováno v:
Viral Immunology. 23:201-210
Bacterial flagellin is a potent adjuvant that enhances adaptive immune responses to a variety of protein antigens. The vaccinia virus antigens L1R and B5R are highly immunogenic in the context of the parent virus, but recombinant forms of the protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3debc07315ff93610326dafb312b56ba
https://doi.org/10.1089/vim.2009.0107
https://doi.org/10.1089/vim.2009.0107
Publikováno v:
Vaccine. 27:6762-6769
There is currently no approved vaccine against Pseudomonas aeruginosa, the major cause of morbidity and mortality in cystic fibrosis (CF) patients and a major pathogen in ventilated and burn patients. In a previous study, we demonstrated the immuniza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0338ba432fa9a918902198a5b98ab2
https://doi.org/10.1016/j.vaccine.2009.08.080
https://doi.org/10.1016/j.vaccine.2009.08.080
Publikováno v:
The Journal of Immunology. 182:7539-7547
Flagellin is a highly effective adjuvant, but the cellular mechanism underlying this activity remains uncertain. More specifically, no consensus exists as to whether flagellin activates dendritic cells (DC) directly or indirectly. Intramuscular immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a575a437634b7b50a7804591d07174d
https://doi.org/10.4049/jimmunol.0804225
https://doi.org/10.4049/jimmunol.0804225
Publikováno v:
Infection and Immunity. 77:2356-2366
Although chronic Pseudomonas aeruginosa infection is the major cause of morbidity and mortality in cystic fibrosis (CF) patients, there is no approved vaccine for human use against P. aeruginosa . The goal of this study was to establish whether a mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c27b9bd920e337422303f530b778ea
https://doi.org/10.1128/iai.00054-09
https://doi.org/10.1128/iai.00054-09
Autor:
Subhashini Arimilli, Steven B. Mizel, John B. Johnson, Aaron H. Graff, Martha A. Alexander-Miller, Kimberly M. Clark, Griffith D. Parks
Publikováno v:
Journal of Virology. 82:10975-10985
The paramyxovirus simian virus 5 (SV5) is a poor activator of human dendritic cell (DC) maturation pathways in vitro, and infected DC do not upregulate cell surface costimulatory proteins or secretion of immunomodulatory cytokines. We evaluated the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104de5da7c3ab5c1452257bcf74bbd40
https://doi.org/10.1128/jvi.01288-08
https://doi.org/10.1128/jvi.01288-08