Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Steven B. Guntrip"'
Autor:
John Dawson, Michael David Barker, Stuart Holman, Joanne O. Wiseman, Margarete Neu, Lisa E. Ranshaw, Fiona S. Lucas, Duncan S. Holmes, Michael Kranz, Christopher J. Delves, Beth J. Clarke, Woodrow Michael David, Tony W. Dean, Don O. Somers, Steven B. Guntrip, Stuart P. Ballantine, Yemisi E. Solanke, Mika K. Lindvaal, Sharon Lisa Gough, Brian Evans, Ward Peter
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1380-1385
Crystallography driven optimisation of a lead derived from similarity searching of the GSK compound collection resulted in the discovery of quinoline-3-carboxamides as highly potent and selective inhibitors of phosphodiesterase 4B. This series has be
Autor:
Michael D. Woodrow, Stuart P. Ballantine, Michael D. Barker, Beth J. Clarke, John Dawson, Tony W. Dean, Christopher J. Delves, Brian Evans, Sharon L. Gough, Steven B. Guntrip, Stuart Holman, Duncan S. Holmes, Michael Kranz, Mika K. Lindvaal, Fiona S. Lucas, Margarete Neu, Lisa E. Ranshaw, Yemisi E. Solanke, Don O. Somers, Peter Ward, Joanne O. Wiseman
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(17)
Crystallography driven optimisation of a lead derived from similarity searching of the GSK compound collection resulted in the discovery of quinoline-3-carboxamides as highly potent and selective inhibitors of phosphodiesterase 4B. This series has be