Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Steven B, Marston"'
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The measurement of the contractile behavior of single cardiomyocytes has made a significant contribution to our understanding of the physiology and pathophysiology of the myocardium. However, the isolation of cardiomyocytes introduces various technic
Externí odkaz:
https://doaj.org/article/58901f24326143c080cf67d9ff4e7539
Autor:
Alice Sheehan, Andrew E. Messer, Maria Papadaki, Afnan Choudhry, Vladimír Kren, David Biedermann, Brian Blagg, Anuj Khandelwal, Steven B. Marston
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The inherited cardiomyopathies, hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are relatively common, potentially life-threatening and currently untreatable. Mutations are often in the contractile proteins of cardiac muscle and ca
Externí odkaz:
https://doaj.org/article/9f4cc4a1c9ae44e7b2ed21de81cc6c4f
Autor:
Andrew E. Messer, Jasmine Chan, Alex Daley, O'Neal Copeland, Steven B. Marston, David J. Connolly
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll. Hom
Externí odkaz:
https://doaj.org/article/a15b31b712f7450db776b864cdd7c907
Autor:
Petr G. Vikhorev, Natalia Smoktunowicz, Alex B. Munster, O’ Neal Copeland, Sawa Kostin, Cecile Montgiraud, Andrew E. Messer, Mohammad R. Toliat, Amy Li, Cristobal G. dos Remedios, Sean Lal, Cheavar A. Blair, Kenneth S. Campbell, Maya Guglin, Manfred Richter, Ralph Knöll, Steven B. Marston
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-2 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/7e904c4780cb44de9c6ada44be61cfe2
Autor:
Pieter de Tombe, Sean Lal, Natalia N. Vikhoreva, Kenneth S. Campbell, Magdi H. Yacoub, WaiChun Yeung, Amy Li, Steven B. Marston, Petr G. Vikhorev, Maya Guglin, Cristobal G. dos Remedios, Cheavar A. Blair
Publikováno v:
Cardiovascular Research
Aims Dilated cardiomyopathy (DCM) is associated with mutations in many genes encoding sarcomere proteins. Truncating mutations in the titin gene TTN are the most frequent. Proteomic and functional characterizations are required to elucidate the origi
Autor:
Hannah Karp, J. Carter Ralphe, Zachery R. Gregorich, Willem J. de Lange, Timothy J. Kamp, Ying Ge, Elizabeth F. Bayne, Trisha Tucholski, Wenxuan Cai, Joshua L. Hermsen, Sean J. McIlwain, Amy Li, Steven B. Marston, Stanford D. Mitchell, Petr G. Vikhorev, Zachary Hite, Cristobal G. dos Remedios, Max Wrobbel, Sean Lal, Takushi Kohmoto, Richard L. Moss
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Hypertrophic cardiomyopathy (HCM) is a common genetic heart disease and a leading cause of sudden cardiac death in young adults. HCM has been linked to mutations in genes encoding sarcomeric proteins, but how different mutations can resu
Autor:
Maria Papadaki, Adam Jacques, Andrew E. Messer, Emma Dyer, Steven B. Marston, Christopher R. Bayliss, Massimiliano Memo
Publikováno v:
Biophysical Reviews
Human heart samples from the Sydney Heart Bank have become a de facto standard against which others can be measured. Crucially, the heart bank contains a lot of donor heart material: for most researchers this is the hardest to obtain and yet is neces
Autor:
Elumalai, Pavadai, Michael J, Rynkiewicz, Zeyu, Yang, Ian R, Gould, Steven B, Marston, William, Lehman
Publikováno v:
Archives of Biochemistry and Biophysics. 725:109282
Tropomyosin, controlled by troponin-linked Ca
Autor:
Steven B. Marston, Juan Eiros Zamora
Publikováno v:
Journal of Muscle Research and Cell Motility
The molecular mechanism by which Ca2+ binding and phosphorylation regulate muscle contraction through Troponin is not yet fully understood. Revealing the differences between the relaxed and active structure of cTn, as well as the conformational chang
Autor:
Khulud Alsulami, Steven B. Marston
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9599, p 9599 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are the most prevalent forms of the chronic and progressive pathological condition known as cardiomyopathy. These diseases have different aetiologies; however, they share the feature