Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Steven B, Hansel"'
Autor:
Marilyn E. Morris, Steven B. Hansel
Publikováno v:
Journal of Pharmacokinetics and Biopharmaceutics. 24:219-243
Conjugation/deconjugation cycling plays an important role in the physiologic regulation of the concentration of endogenous compounds that form conjugated metabolites. Less is known concerning the deconjugation of xenobiotics. The model compound p-nit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c121d48858e9d14cc93fb51b931de0
https://doi.org/10.1007/bf02353490
https://doi.org/10.1007/bf02353490
Autor:
Steven B. Hansel, Marilyn E. Morris
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 532:285-293
p-Nitrophenol (pNP) and its conjugated metabolites, generated in a perfused rat liver preparation, are readily separated and quantitated in serum perfusate and bile samples using a reverse-phase high-performance liquid chromatographic method. Serum p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1c3bb2506806cde92e7a9927e8f811
https://doi.org/10.1016/s0378-4347(00)83779-2
https://doi.org/10.1016/s0378-4347(00)83779-2
Autor:
C V C, Prasad, Owen B, Wallace, Jeffrey W, Noonan, Charles P, Sloan, Wai, Lau, Shikha, Vig, Michael F, Parker, David W, Smith, Steven B, Hansel, Craig T, Polson, Donna M, Barten, Kevin M, Felsenstein, Susan B, Roberts
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(8)
Using a cell-based assay, we have identified optimal residues and key recognition elements necessary for inhibition of gamma-secretase. An (S)-hydroxy group or 3,5-difluorophenylacetyl group at the amino terminus and N-methyltertiary amide moiety at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216cca58efa4310505e38e5be20e637b
https://pubmed.ncbi.nlm.nih.gov/15050627
https://pubmed.ncbi.nlm.nih.gov/15050627