Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Steven B, Abramson"'
Autor:
Virginia Byers Kraus, Alexander Reed, Erik J. Soderblom, M. Arthur Moseley, Ming-Feng Hsueh, Mukundun G. Attur, Jonathan Samuels, Steven B. Abramson, Yi-Ju Li
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 1, Pp 100425- (2024)
Objective: To further validate a serum proteomics panel for predicting radiographic (structural) knee OA progression. Design: Serum peptides were targeted by multiple-reaction-monitoring mass spectrometry in the New York University cohort (n =
Externí odkaz:
https://doaj.org/article/004b8865f9564922b46dfd78e1c4383f
Autor:
Anne C. Bay-Jensen, Mukundan Attur, Jonathan Samuels, Christian S. Thudium, Steven B. Abramson, Morten A. Karsdal
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 5, Iss 3, Pp 100379- (2023)
Background: The lack of disease modifying drugs in Osteoarthritis (OA) may be attributed to the difficulty in robust response based on patient-reported outcomes (PROs) linked to drug mechanism of action. Joint tissue turnover biomarkers are associate
Externí odkaz:
https://doaj.org/article/2f013bd017994433b08da053806363eb
Autor:
Mukundan Attur, Xin Duan, Lei Cai, Tianzhen Han, Weili Zhang, Eric D. Tycksen, Jonathan Samuels, Robert H. Brophy, Steven B. Abramson, Muhammad Farooq Rai
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background Elevated levels of periostin (Postn) in the cartilage and bone are associated with osteoarthritis (OA). However, it remains unknown whether Postn loss-of-function can delay or prevent the development of OA. In this study, we sough
Externí odkaz:
https://doaj.org/article/539326da7b6e4804afcdfd7eb108f332
Autor:
Yunyun Luo, Jonathan Samuels, Svetlana Krasnokutsky, Inger Byrjalsen, Virginia B. Kraus, Yi He, Morten A. Karsdal, Steven B. Abramson, Mukundan Attur, Anne C. Bay-Jensen
Publikováno v:
Journal of Orthopaedics and Traumatology, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Osteoarthritis (OA) is a disease with multiple endotypes. A hallmark of OA is loss of cartilage; however, it is evident that the rate of cartilage loss differs among patients, which may partly be attributed to differential capacit
Externí odkaz:
https://doaj.org/article/fe780c80254c4b1aad37ba8138ac360d
Autor:
Mukundan Attur, Svetlana Krasnokutsky, Hua Zhou, Jonathan Samuels, Gregory Chang, Jenny Bencardino, Pamela Rosenthal, Leon Rybak, Janet L. Huebner, Virginia B. Kraus, Steven B. Abramson
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-17 (2020)
Abstract Objective Predictive biomarkers of progression in knee osteoarthritis are sought to enable clinical trials of structure-modifying drugs. A peripheral blood leukocyte (PBL) inflammatory gene signature, MRI-based bone marrow lesions (BML) and
Externí odkaz:
https://doaj.org/article/609d3b655b50445fa3b8c11215d798ff
Publikováno v:
Cells, Vol 11, Iss 15, p 2436 (2022)
Rheumatoid arthritis is a chronic systemic immune-mediated disease caused by genetic and environmental factors. It is often characterized by the generation of autoantibodies that lead to synovial inflammation and eventual multi-joint destruction. A g
Externí odkaz:
https://doaj.org/article/5713e38e340c4b1e8957c9ae70ba5605
Autor:
Tal Baron, Robert I Grossman, Steven B Abramson, Martin V Pusic, Rafael Rivera, Marc M Triola, Itai Yanai
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227108 (2020)
The acceptance of students to a medical school places a considerable emphasis on performance in standardized tests and undergraduate grade point average (uGPA). Traditionally, applicants may be judged as a homogeneous population according to simple q
Externí odkaz:
https://doaj.org/article/1ee40887f4fa40299eb8ea4263692c24
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231501 (2020)
Osteoarthritis (OA) is characterized by progressive loss of articular cartilage accompanied by the new bone formation and, often, a synovial proliferation that culminates in pain, loss of joint function, and disability. However, the cellular and mole
Externí odkaz:
https://doaj.org/article/d80471055d814a9689afcd5235349ec1
Publikováno v:
Medical Education Online, Vol 21, Iss 0, Pp 1-8 (2016)
Background: A handful of medical schools in the U.S. are awarding medical degrees after three years. While the number of three-year pathway programs is slowly increasing there is little data on the opinions of medical education leaders on the need fo
Externí odkaz:
https://doaj.org/article/3e5da8c2864c49bc853cf531546ee606
Autor:
Mukundan Attur, Christopher Petrilli, Samrachana Adhikari, Eduardo Iturrate, Xiyue Li, Stephanie Tuminello, Nan Hu, Aravinda Chakravarti, David Beck, Steven B. Abramson
Publikováno v:
medRxiv
ObjectiveTo explore the regulation of the inflammatory response in acute SARS-CoV-2 infection, we examined effects of single nucleotide variants (SNVs) ofIL1RN, the gene encoding the anti-inflammatory IL-1 receptor antagonist (IL-1Ra), on the cytokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a693885a52fbca8a45a7e99961539c69
https://europepmc.org/articles/PMC9882468/
https://europepmc.org/articles/PMC9882468/
