Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Steven A. Zimmerman"'
Publikováno v:
ACS Chemical Biology. 17:1103-1110
Disease intervention at the DNA level generally has been avoided because of off-target effects. Recent advances in genome editing technologies using CRISPR-Cas9 have opened a new era in DNA-targeted therapeutic approaches. However, delivery of such s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8878b2b6c34af84a69233d9e4fa04cfb
https://doi.org/10.1021/acschembio.1c00949
https://doi.org/10.1021/acschembio.1c00949
Publikováno v:
Journal of Chemical Education. 99:1802-1807
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f01e1fa4bf5feda4f1e17c3632994e9
https://doi.org/10.1021/acs.jchemed.1c01049
https://doi.org/10.1021/acs.jchemed.1c01049
Autor:
Steven C. Zimmerman
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 125-138 (2016)
This review summarizes part of the author’s research in the area of supramolecular chemistry, beginning with his early life influences and early career efforts in molecular recognition, especially molecular tweezers. Although designed to complex DN
Externí odkaz:
https://doaj.org/article/f70f0a6b64c24f489fc375bb729e2d3f
Autor:
Steven C. Zimmerman, Sarah Krueger
Publikováno v:
Journal of medicinal chemistry. 65(18)
Trinucleotide repeat diseases such as myotonic dystrophy type 1 (DM1) and Huntington's disease (HD) are caused by expanded DNA repeats that can be used as templates to synthesize their own inhibitors. Because it would be particularly advantageous to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb46f85304c6dceb9d3ed2a411aa50e
https://pubmed.ncbi.nlm.nih.gov/36099320
https://pubmed.ncbi.nlm.nih.gov/36099320
Publikováno v:
ChemBioChem. 23
Small molecule targeting of DNA and RNA sequences has come into focus as a therapeutic strategy for diseases such as myotonic dystrophy type 1 (DM1), a trinucleotide repeat disease characterized by RNA gain-of-function. Herein, we report a novel temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f36311487669856a8e849ba94b36b54
https://doi.org/10.1002/cbic.202200260
https://doi.org/10.1002/cbic.202200260
Publikováno v:
Polymer Chemistry. 12:6755-6760
A Ru-containing single chain nanoparticle (SCNP) was prepared in three steps using radical polymerization of pentafluorophenylacrylate, post-polymerization functionalization with three different alkylamines, and coordination of Ru. The polymer was ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d2f6d1d160facd51a202114b898f702
https://doi.org/10.1039/d1py01255j
https://doi.org/10.1039/d1py01255j
Autor:
Junfeng Chen, Ruixian Zhang, Uzoma O. Nwabara, Nawal M. Alghoraibi, Xinyi Chen, Steven C. Zimmerman, Danielle A. Henckel, Kenneth E. Madsen, Paul J. A. Kenis, Andrew A. Gewirth
Publikováno v:
Nature Catalysis. 4:20-27
Electrochemical conversion of CO2 into value-added chemicals holds promise to enable the transition to carbon neutrality. Enhancing selectivity for a specific hydrocarbon product is challenging, however, due to numerous possible reaction pathways of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c1649ee54c9a8547d1254a0c88529c
https://doi.org/10.1038/s41929-020-00547-0
https://doi.org/10.1038/s41929-020-00547-0
Autor:
Keith Harris, Brenda Andrade, Samuel N. Knewstub, Christopher J. Tucker, Joshua S. Katz, Steven C. Zimmerman
Publikováno v:
Langmuir. 36:10103-10109
The surfactant properties of amphiphilic hyperbranched polyglycerols (HPGs) were investigated. The HPGs were prepared by ring-opening multibranching polymerization of glycidol using hydrophobic initiators of varying size and structure. The cloud poin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0b4fa7ffa09c1e331bd114dca27dc5
https://doi.org/10.1021/acs.langmuir.0c01349
https://doi.org/10.1021/acs.langmuir.0c01349
Publikováno v:
Accounts of Chemical Research. 53:1244-1256
Cross-linking of polymers significantly alters their physical properties, greatly expanding their everyday utility. Indeed, the polymeric networks resulting from linkages between polymer chains are found in everyday materials from soft contact lenses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e9a6751c2498a958c7c210cf9971e5
https://doi.org/10.1021/acs.accounts.0c00178
https://doi.org/10.1021/acs.accounts.0c00178
Publikováno v:
Chemical Science
A new type of base-triggered self-amplifying degradable polyurethane is reported that degrades under mild conditions, with the release of increasing amounts of amine product leading to self-amplified degradation. The polymer incorporates a base-sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb15a37eea82c805165a80c20b4f120
http://europepmc.org/articles/PMC8152679
http://europepmc.org/articles/PMC8152679