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pro vyhledávání: '"Steven A. Keatch"'
Publikováno v:
Nucleic Acids Research
Flyvbjerg, H, Keatch, S A & Dryden, D T F 2006, ' Strong physical constraints on sequence-specific target location by proteins on DNA molecules ', Nucleic Acids Research, vol. 34, no. 9, pp. 2550-2557 . https://doi.org/10.1093/nar/gkl271
Flyvbjerg, H, Keatch, S A & Dryden, D T F 2006, ' Strong physical constraints on sequence-specific target location by proteins on DNA molecules ', Nucleic Acids Research, vol. 34, no. 9, pp. 2550-2557 . https://doi.org/10.1093/nar/gkl271
Sequence-specific binding to DNA in the presence of competing non-sequence-specific ligands is a problem faced by proteins in all organisms. It is akin to the problem of parking a truck at a loading bay by the side of a road in the presence of cars p
Publikováno v:
Keatch, S A, Leonard, P G, Ladbury, J E & Dryden, D T F 2005, ' StpA protein from Escherichia coli condenses supercoiled DNA in preference to linear DNA and protects it from digestion by DNase I and EcoKI ', Nucleic Acids Research, vol. 33, no. 20, pp. 6540-6546 . https://doi.org/10.1093/nar/gki951
Nucleic Acids Research
Nucleic Acids Research
The nucleoid-associated protein, StpA, of Escherichia coli binds non-specifically to double-stranded DNA (dsDNA) and apparently forms bridges between adjacent segments of the DNA. Such a coating of protein on the DNA would be expected to hinder the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f970e270c042acd378db708b26e32e
Publikováno v:
Keatch, S A, Su, T J & Dryden, D T F 2004, ' Alleviation of restriction by DNA condensation and non-specific DNA binding ligands ', Nucleic Acids Research, vol. 32, no. 19, pp. 5841-5850 . https://doi.org/10.1093/nar/gkh918
During conditions of cell stress, the type I restriction and modification enzymes of bacteria show reduced, but not zero, levels of restriction of unmethylated foreign DNA. In such conditions, chemically identical unmethylated recognition sequences a
Autor:
Deepa Rangar, Steven A. Keatch, Peter C. Hayes, Celine Filippi, Leonard J Nelson, John N. Plevris
Publikováno v:
Journal of hepatology. 41(4)
Background/Aims The use of cell lines in bioartificial liver support systems (BALSS) to treat fulminant hepatic failure (FHF) is hindered by their reduced metabolic functions, which could be further decreased by the patient's serum/plasma. Hence, the