Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Steven A. Gunzler"'
Autor:
Zerui Wang, Tricia Gilliland, Hyun Jo Kim, Maria Gerasimenko, Kailey Sajewski, Manuel V. Camacho, Gurkan Bebek, Shu G. Chen, Steven A. Gunzler, Qingzhong Kong
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Seeding activities of disease-associated α-synuclein aggregates (αSynD), a hallmark of Parkinson’s disease (PD), are detectable by seed amplification assay (αSyn-SAA) and being developed as a diagnostic biomarker for PD. Sensitive and a
Externí odkaz:
https://doaj.org/article/4c4934e62fea43468d3272fed2237ea8
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Loss of ambulation is common and highly variable in Parkinson’s disease (PD), and poorly understood from the perspectives of those with PD. Gaining insights to the anticipated perceived trajectories and their drivers, will facilitate patie
Externí odkaz:
https://doaj.org/article/3f92da58f6a84dbf8c42b661a5ea348f
Autor:
Anastasia Kuzkina, Connor Bargar, Daniela Schmitt, Jonas Rößle, Wen Wang, Anna-Lena Schubert, Curtis Tatsuoka, Steven A. Gunzler, Wen-Quan Zou, Jens Volkmann, Claudia Sommer, Kathrin Doppler, Shu G. Chen
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Skin α-synuclein deposition is considered a potential biomarker for Parkinson’s disease (PD). Real-time quaking-induced conversion (RT-QuIC) is a novel, ultrasensitive, and efficient seeding assay that enables the detection of minute amou
Externí odkaz:
https://doaj.org/article/3a90bad7b05e46a19ec4caa217356998
Autor:
Connor Bargar, Wen Wang, Steven A. Gunzler, Alexandra LeFevre, Zerui Wang, Alan J. Lerner, Neena Singh, Curtis Tatsuoka, Brian Appleby, Xiongwei Zhu, Rong Xu, Vahram Haroutunian, Wen-Quan Zou, Jiyan Ma, Shu G. Chen
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Definitive diagnosis of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) relies on postmortem finding of disease-associated alpha-synuclein (αSynD) as misfolded protein aggregates in the central nervous system (CNS). The recen
Externí odkaz:
https://doaj.org/article/428f2d50f8b04b48843f8d5fdc2cbb25
Autor:
Anne-Marie, Wills, Alexander, Pantelyat, Alberto, Espay, James, Chan, Irene, Litvan, Tao, Xie, Marian L, Dale, Steven A, Gunzler, Maria Carmela, Tartaglia, Susan H, Fox, Federico, Rodriguez-Porcel, Mansi, Sharma, Anthony E, Lang, Adam L, Boxer, Lawrence I, Golbe
Publikováno v:
Movement Disorders. 37:1265-1271
The reliability of the Progressive Supranuclear Palsy Rating Scale (PSPRS) using teleneurology has not been assessed.To test whether removing items inadequately assessed by video would impact measurement of PSP severity and progression.We performed s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d14ed42afed8418752a6dbe05185d3f
https://doi.org/10.1002/mds.28991
https://doi.org/10.1002/mds.28991
Publikováno v:
Parkinsonism & Related Disorders. 111:105433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114e6da435ed9db1cf38eb834bbfae95
https://doi.org/10.1016/j.parkreldis.2023.105433
https://doi.org/10.1016/j.parkreldis.2023.105433
Publikováno v:
Parkinsonismrelated disorders. 102
Pain is a common and complex symptom in Parkinson's disease. The underlying mechanisms and longitudinal patterns are not well understood, which impedes therapeutic decision making. The objectives of this study were to characterize longitudinal pain t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ed0f27a98336a854072f2bcf0e9473
https://pubmed.ncbi.nlm.nih.gov/35933822
https://pubmed.ncbi.nlm.nih.gov/35933822
Autor:
Connor Bargar, Chiara Maria Giulia De Luca, Grazia Devigili, Antonio Emanuele Elia, Roberto Cilia, Sara Maria Portaleone, Wen Wang, Irene Tramacere, Edoardo Bistaffa, Federico Angelo Cazzaniga, Giovanni Felisati, Giuseppe Legname, Alessio Di Fonzo, Rong Xu, Steven Alexander Gunzler, Giorgio Giaccone, Roberto Eleopra, Shu Guang Chen, Fabio Moda
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-19 (2021)
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-19 (2021)
Background Detection of the pathological and disease-associated alpha-synuclein (αSynD) in the brain is required to formulate the definitive diagnosis of multiple system atrophy (MSA) and Parkinson’s disease (PD). We recently showed that αSynD ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0326b35c8ccba5c2e16d5bf05fb4cc8
https://doi.org/10.1186/s13024-021-00491-y
https://doi.org/10.1186/s13024-021-00491-y
Autor:
Anne‐Marie Wills, Lawrence I. Golbe, Anthony E. Lang, Tao Xie, Marian L. Dale, Alberto Espay, Maria Carmela Tartaglia, Susan H. Fox, Sotirios Andreas Parashos, Nikolaus R. McFarland, Ruth B. Schneider, Federico Rodriguez‐Porcel, Steven A. Gunzler, Alexander Pantelyat
Publikováno v:
Mov Disord
BACKGROUND: The reliability of the Progressive Supranuclear Palsy Rating Scale (PSPRS) using teleneurology has not been assessed. OBJECTIVES: To test whether removing items inadequately assessed by video would impact measurement of PSP severity and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ae7fa629eae74a9a37e3840f8f62cb
https://doi.org/10.1002/mds.29142
https://doi.org/10.1002/mds.29142
Autor:
Tanya Simuni, Holly A. Shill, Matthew Brodsky, Marcie Rabin, Michael A. Schwarzschild, Kenneth Marek, Cheryl Waters, Cindy Casaceli, Steven A. Gunzler, Stephen G. Reich, Codrin Lungu, Sarah Elizabeth Zauber, Kellie Keith, Shyamal H. Mehta, Dariush Mozaffarian, Valerie Suski, Marie Saint-Hilaire, John L. Goudreau, Alice Rudolph, Ruth B. Schneider, Aaron Daley, Eric A. Macklin, Zoltan Mari, Grace F. Crotty, Andres Deik, Alberto J. Espay, Ashley Laroche, Sherri Mosovsky, Joohi Jimenez-Shahed, Mark S. LeDoux, Cynthia Poon, Ashley Gerald, John C. Morgan, Carolyn Peterson, Joseph H. Friedman, David Klements, Robert A. Hauser, Doozie Russell, David Simon, Kathrin LaFaver, Vanessa K. Hinson, Richard B. Dewey, Melissa Ainslie, Jason Aldred, Tiago A. Mestre, John Y. Fang, Liana S. Rosenthal, Grace Bwala, Raymond C. James, Binit B. Shah, Gearoid M. McMahon, Ariane Park, Rajeev Kumar, Lin Zhang, Ivan Bodis-Wollner, Mya C. Schiess, Katherine F. Callahan, David Oakes, Kelvin L. Chou, Melissa Kostrzebski, Roger Kurlan, Lisa Gauger, Albert Y. Hung, Melissa Bixby, Ira Shoulson, Michael Soileau, James T. Boyd, Peter A LeWitt, Burton L. Scott, Claire Henchcliffe, Patricia Kaminski, Alberto Ascherio, Cornelia Kamp, Lindsay Pothier, Anwar Ahmed, Jill Ciccarello, David J. Houghton, April Langhammer, Rebecca Fitzgerald, Maureen A. Leehey, Anthony E. Lang, Carmen Serrano, Martha McGraw, David Shprecher, Jennifer Durphy, Aleksandar Videnovic, Danish Bhatti, Christine Hunter, Amber Servi Ratel, J. Antonelle de Marcaida, Christopher G. Goetz, Emily Houston, Rajesh Pahwa, Chadwick W. Christine, Gary C. Curhan, Irene Litvan, Christopher A. Beck, Leslie J. Cloud, Patrick Bolger, Karen Thomas, Natividad Stover, Karen Blindauer, Sushrut S. Waikar, Susan R. Criswell
Publikováno v:
JAMA
IMPORTANCE: Urate elevation, despite associations with crystallopathic, cardiovascular, and metabolic disorders, has been pursued as a potential disease-modifying strategy for Parkinson disease (PD) based on convergent biological, epidemiological, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4608ea519947a922d23da1991ccca9
https://europepmc.org/articles/PMC8441591/
https://europepmc.org/articles/PMC8441591/
