Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Steven A. Block"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
RNA sequence-structure-function relationships can be studied via assays of variant activity. The authors developed a method to systematically determine ribozyme variant kinetics, using it to map double-mutant interactions and show that cleavage rate
Externí odkaz:
https://doaj.org/article/bd2de6930e9143e08b42ce2dd005876a
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Contacts between RNA polymerase and promoter DNA modulate the strength of binding and the frequency of promoter escape during transcription. Here, the authors describe a single molecule optical-trapping assay to study transcription initiation and obs
Externí odkaz:
https://doaj.org/article/3bd3119120af44ce91cb96c3a3fcba13
Publikováno v:
Food Security. 14:93-109
This paper advances previous literature that has posited a climate-nutrition link without identifying a specific pathway via agriculture. We measure the specific effects of exposure to extreme heat on maize yields in Tanzania, and then test whether p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cae5eb6b2c66e543fa75850d8fb268c3
https://doi.org/10.1007/s12571-021-01211-6
https://doi.org/10.1007/s12571-021-01211-6
Publikováno v:
Handbook of Agricultural Economics ISBN: 9780323988858
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::594c6a14bf21a0e34848485977d59bfb
https://doi.org/10.1016/bs.hesagr.2022.03.006
https://doi.org/10.1016/bs.hesagr.2022.03.006
Publikováno v:
eLife, Vol 4 (2015)
The thiamine pyrophosphate (TPP) riboswitch is a cis-regulatory element in mRNA that modifies gene expression in response to TPP concentration. Its specificity is dependent upon conformational changes that take place within its aptamer domain. Here,
Externí odkaz:
https://doaj.org/article/50e615842bf24d379d6461b505b5e887
Autor:
Johan OL Andreasson, Bojan Milic, Geng-Yuan Chen, Nicholas R Guydosh, William O Hancock, Steven M Block
Publikováno v:
eLife, Vol 4 (2015)
Kinesin-1 is a dimeric motor that transports cargo along microtubules, taking 8.2-nm steps in a hand-over-hand fashion. The ATP hydrolysis cycles of its two heads are maintained out of phase by a series of gating mechanisms, which lead to processive
Externí odkaz:
https://doaj.org/article/83ab9678951646c7be4c7c9bd14a6bcc
Publikováno v:
Food Policy
Graphical abstract
Highlights • Policies and programs often aim to bring nutritious diets within reach of the poor. • We use food prices and composition to compare least-cost diets around the world. • Globally, nutrient adequacy costs 2.66
Highlights • Policies and programs often aim to bring nutritious diets within reach of the poor. • We use food prices and composition to compare least-cost diets around the world. • Globally, nutrient adequacy costs 2.66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6753bfd8dd058da4cd94a87f02e2e1c3
https://pubmed.ncbi.nlm.nih.gov/33767525
https://pubmed.ncbi.nlm.nih.gov/33767525
Autor:
Dariush Mozaffarian, Timothy S. Griffin, Eileen Kennedy, Rachel Kyte, Steven A. Block, Patrick Webb
Publikováno v:
Current Developments in Nutrition
Food systems lie squarely at the intersection of several overarching goals of the UN and member states, as embodied in the Sustainable Development Goals, including eliminating poverty, hunger, and malnutrition in all its forms, achieving good health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf7f6710e0c9af225496c2c32e8243f
https://pubmed.ncbi.nlm.nih.gov/33501403
https://pubmed.ncbi.nlm.nih.gov/33501403
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Massively parallel, quantitative measurements of biomolecular activity across sequence space can greatly expand our understanding of RNA sequence-function relationships. We report the development of an RNA-array assay to perform such measurements and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4626c73fc88e13b4f6bbfc5a0585352
https://escholarship.org/uc/item/7tz0p2xn
https://escholarship.org/uc/item/7tz0p2xn
Autor:
Steven M. Block, Andrew Savinov
Publikováno v:
Proceedings of the National Academy of Sciences. 115:11976-11981
Significance Riboswitches are structured mRNA elements that regulate gene expression in response to metabolite ligands. The bacterial glmS riboswitch regulates a protein with a key role in cell wall biosynthesis. This riboswitch follows an unusual me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3128de423a2c670ec00426ac969ce632
https://doi.org/10.1073/pnas.1812122115
https://doi.org/10.1073/pnas.1812122115