Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Steven A. Beasley"'
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235925 (2020)
Angelman syndrome (AS) is a rare neurodevelopmental disorder characterized by speech impairment, intellectual disability, ataxia, and epilepsy. AS is caused by mutations in the maternal copy of UBE3A located on chromosome 15q11-13. UBE3A codes for E6
Externí odkaz:
https://doaj.org/article/c2464bd04c6e4439a11756360d9052eb
Autor:
Emma I. Kane, Steven A. Beasley, Johanna M. Schafer, Justine E. Bohl, Young Sun Lee, Kayla J. Rich, Elizabeth F. Bosia, Donald E. Spratt
Publikováno v:
Bioscience Reports. 42
There are 28 unique human members of the homologous to E6AP C-terminus (HECT) E3 ubiquitin ligase family. Each member of the HECT E3 ubiquitin ligases contains a conserved bilobal HECT domain of approximately 350 residues found near their C-termini t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7303e1957c113add40e7a1f09119bbb5
https://doi.org/10.1042/bsr20221036
https://doi.org/10.1042/bsr20221036
Publikováno v:
Encyclopedia of Signaling Molecules ISBN: 9781461464389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f651aacb9a21c0cea2bff8c5887f6f7
https://doi.org/10.1007/978-3-319-67199-4_101592
https://doi.org/10.1007/978-3-319-67199-4_101592
Publikováno v:
Protein science : a publication of the Protein Society. 21(7)
The E3 ligases HOIL-1 and parkin are each comprised of an N-terminal ubiquitin-like (Ubl) domain followed by a zinc-binding region and C-terminal RING–In-between-RING–RING domains. These two proteins, involved in the ubiquitin-mediated degradatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f10b2107d05df2f8eda04f085a82fc8
https://pubmed.ncbi.nlm.nih.gov/22517668
https://pubmed.ncbi.nlm.nih.gov/22517668